Traditional Chinese medicine composition for preventing fracture postoperative lower limb deep venous thrombosis, and preparation method thereof

A technology of deep vein thrombosis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for preventing deep vein thrombosis of lower extremities after fracture surgery, can solve the problems of high risk, bleeding adverse events, and high cost, and achieve the prevention of DVT, The effect of improving the stasis state and restoring the gasification function

Pending Publication Date: 2020-05-26
XIAN HONGHUI HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Western medicine mainly uses anticoagulant drugs for prevention, ...

Method used

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Embodiment 1

[0031] A traditional Chinese medicine composition for preventing deep vein thrombosis of lower extremities after fracture operation, which is a medicament made of the following traditional Chinese medicine raw materials in weight ratio:

[0032] 15 parts of astragalus, 10 parts of angelica, 10 parts of cassia twig, 5 parts of chuanxiong, 5 parts of peach kernel, 5 parts of safflower, 3 parts of ground dragon powder, 3 parts of leech powder, and 3 parts of panax notoginseng.

Embodiment 2

[0034] A traditional Chinese medicine composition for preventing deep vein thrombosis of lower extremities after fracture operation, which is a medicament made of the following traditional Chinese medicine raw materials in weight ratio:

[0035] 45 parts of astragalus, 20 parts of angelica, 20 parts of cassia twig, 15 parts of Chuanxiong, 15 parts of peach kernel, 15 parts of safflower, 9 parts of earthworm powder, 9 parts of leech powder, and 9 parts of notoginseng.

Embodiment 3

[0037] Below, introduce a preferred embodiment of the present invention in conjunction with clinical data:

[0038] 1 Materials and methods

[0039] 1.1 General information 1860 patients with lower extremity fractures who were admitted to Xi'an Honghui Hospital from October 2016 to October 2019 were admitted for ultrasound examination of the veins of both lower extremities. The average age of all patients was 49.6 years; they were randomly divided into experimental group and control group. There was no statistically significant difference between the two groups in the incidence of DVT, age, sex, comorbidities and other general information at admission (P>0.05), and they were comparable.

[0040] 1.2 Method

[0041] Control group: low molecular weight heparin calcium 4100U, subcutaneous injection, once a day;

[0042] Experimental group: adopt Chinese medicine prescription treatment of the present invention: Astragalus 30g, Angelica 15g, Guizhi 15g, Rhizoma Chuanxiong 10g, p...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing fracture postoperative lower limb deep venous thrombosis, and a preparation method thereof, and belongs to the field of traditional Chinese medicines. In the traditional Chinese medicine science, the lower limb deep venous thrombosis is caused by trauma, surgery, pregnancy, malignant tumors, long-term bed lying of other diseases and the like, so that qi is injured after long-term sitting and long-term lying; qi deficiency is more serious after trauma and fracture operations; And Qi is a blood commander, unsmoothblood circulation is caused by Qi injury, and slow blood circulation is caused by unsmooth Qi, so that the blood circulation is blocked in the pulse. According to the etiology and pathogenesis of thedisease, astragalus membranaceus, angelica sinensis, cassia twigs, ligusticum wallichII, peach kernels, safflower carthamus, earthworms, leeches, pseudo-ginseng and other medicines are selected, so the composition can achieve qi tonifying and blood activating, remarkably reduces the incidence rate of postoperative deep venous thrombosis of lower limbs after clinical use, and is worthy of clinicalpromotion.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for preventing deep vein thrombosis of lower limbs after fracture operation and a preparation method thereof. Background technique [0002] Deep vein thrombosis (DVT) of the lower extremities refers to the abnormal coagulation of blood in the deep venous cavity, blocking the venous lumen, causing venous return disorders, and causing clinical symptoms such as lower extremity swelling, pain, and venous valve damage. It is a common clinical disease. Peripheral Vascular Disease. [0003] The rate of misdiagnosis and missed diagnosis of DVT is high, and the mortality rate of patients with early diagnosis and reasonable prevention is significantly reduced ( District Kam Yan, Liu Xiaojie, Wu Zhengjie, et al. Significance of preoperative vascular ultrasonography and determination of D-dimer in patients with tr...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P7/02A61P9/14A61K35/62
CPCA61K9/0095A61K35/62A61K36/232A61K36/236A61K36/258A61K36/286A61K36/481A61K36/54A61K36/736A61K2236/331A61K2236/39A61P7/02A61P9/14A61K2300/00
Inventor 王宝辉王鹏飞张堃刘德玉刘娜孙银娣
Owner XIAN HONGHUI HOSPITAL
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