Mesoionic insecticide
An alkyl and compound technology, applied in the directions of insecticides, nematicides, biocides, etc., can solve the problems of pest-resistant insecticides' service life, environmental pollution, and yield reduction, and achieve excellent control effects.
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[0207] Example 1: 1-(2-(dimethylamino)ethyl)-8-methyl-4-oxo-3-phenyl-4H-pyridin[1,2-a]pyrimidin-1-ium Synthesis of -2-alkoxide
[0208]
[0209] Will N 1 ,N 1 -Dimethyl-N 2 -(4-methylpyridin-2-yl)ethane-1,2-diamine (0.179g, 1.00mmol), bis(2,4,6-trichlorophenyl) 2-phenylmalonate (0.805g, 1.50mmol) and toluene (15mL) were added to a 50mL single-necked flask, heated to 110°C under reflux and stirred for 24 hours. The solvent was distilled off under reduced pressure, and the residue was separated by silica gel column chromatography [methanol / ethyl acetate (v:v)=1:20] to obtain the target compound (0.06 g of yellow oil, yield: 18.5%).
[0210] 1 H NMR (DMSO-d 6,400MHz)δ(ppm): 9.28(d,J=8.6Hz,1H),7.81(d,J=8.5Hz,2H),7.48(d,J=15.7,8.7Hz,1H),7.36-7.10( m,3H),7.05-6.98(m,1H),5.15(s,2H),2.48-2.43(m,5H),2.31(s,6H);
[0211] MS(ES-API,pos.ion)m / z:324.51[M+1] + .
[0212] Using intermediates N1 to N6 and intermediates M1 to M7 as reactants respectively, the target compounds in T...
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