A production medical isotope 225 AC method and device

An isotope and medical technology, applied in the field of methods and devices for producing medical isotope 225Ac, can solve the problems of complex process and high cost, and achieve the effects of low cost, low investment and high purity

Active Publication Date: 2022-08-09
西安迈斯拓扑科技有限公司
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Problems solved by technology

[0005] In order to solve the current production 225 The method of Ac has problems such as high cost and complicated process. The invention discloses a method for producing medical isotopes 225 Ac method and apparatus for converting high-power high-energy electron beams to bremsstrahlung bombardment 226 Ra, via photonuclear reaction produce 225 Ac, the method not only does not require expensive 229 Th, and high output, low cost, simple and convenient, no radioactive waste disposal problems

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  • A production medical isotope <sup>225</sup> AC method and device
  • A production medical isotope <sup>225</sup> AC method and device
  • A production medical isotope <sup>225</sup> AC method and device

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Embodiment Construction

[0047] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0048] The invention utilizes high-energy electron beam to irradiate bremsstrahlung conversion target to generate enough X-ray photon beam, and utilizes X-ray photon beam to irradiate 226 Ra sample target; after standing for 18 days, irradiated 225 Ra via beta - decay into a certain amount 225 Ac, again 226 The Ra sample target is chemically dissolved and separated 225 Ac.

[0049] The photonuclear reaction cross section is generally small, but a wide (3-7MeV) giant dipole resonance (GDR) appears in the energy range of 10-25MeV. 226 The photonuclear reaction of Ra will have a relatively high photonuclear reaction cross section, such as image 3 , 226 Ra(γ,n) 225 The photonuclear reaction cross section of Ra is ~290mb. The threshold energy is 6.2MeV and the peak cross-section energy is 12MeV.

[0050] Apart from 226 Ra(γ,n) 225 Ra reac...

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Abstract

The invention belongs to the field of medical radiotherapy nuclides, in particular to a production of medical isotopes 225 Ac method and apparatus. solve current production 225 The method of Ac has problems such as low yield, high cost, and complicated process. It uses high-power high-energy electron beams to convert into bremsstrahlung bombardment. 226 Ra sample target, generated by photonuclear reaction 225 Ac, finally 226 The Ra sample target is chemically dissolved and isolated 225 Ac, the method not only does not require expensive 229 Th, and low cost, simple and convenient, no radioactive waste disposal problem.

Description

technical field [0001] The invention belongs to the field of medical radiotherapy nuclides, in particular to a production of medical isotopes 225 Ac method and apparatus. Background technique [0002] With the continuous update and development of tumor diagnosis and treatment in modern medicine, tumor treatment is developing towards precise targeted therapy. In addition to targeted chemotherapeutics, targeted radionuclide therapy has received more and more attention and has a very broad prospect. Radioisotopes decayed by the release of alpha particles, typically as 225 Ac and 213 Bi ( 213 Bi is 225 The decay progeny of Ac) is rapidly becoming the trend and focus of tumor diagnosis and treatment, especially tumor targeted therapy research. Preclinical animal experimental research and preliminary clinical practice have achieved very successful results. This is mainly because: 1) 225 Ac has excellent nuclear physical properties, short half-life (10 days), and its decay d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G21G1/00
CPCG21G1/001G21G2001/0089
Inventor 张宇皓刘伯学王思弘王柏松
Owner 西安迈斯拓扑科技有限公司
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