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Composition for alleviating and treating hair loss, hair damage, and skin disease of animal, comprising aptamin c as active ingredient

A skin disease and composition technology, which is applied in the direction of medical preparations containing active ingredients, skin diseases, drug combinations, etc., can solve the problems of weakening pet skin tissue immunity, weakening immunity, and heavy economic burden

Pending Publication Date: 2021-07-23
(株)纳斯摩仕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the characteristics of skin diseases that require long-term treatment, excessive use of chemically synthesized drugs containing bactericidal ingredients can weaken the immunity of pets' kidneys, livers, and skin tissues. Moreover, even if expensive ointments, oral preparations or Injection of medicines can also cause recurrence of skin diseases, which cannot be cured
Furthermore, long-term excessive use of chemical synthetic drugs will cause fatal damage to the liver or kidney tissue of pets, and eventually complications will be induced due to the weakening of immunity caused by the weakening of liver and kidney functions
[0020] As mentioned above, in order to treat skin diseases of pets, not only the economic burden is heavy, but also pets need to be cared for for a long time. Furthermore, even if the pets bear the financial burden and continue to care for pets, it is not easy to cure pets' depilation, hair damage, skin damage, etc. disease

Method used

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  • Composition for alleviating and treating hair loss, hair damage, and skin disease of animal, comprising aptamin c as active ingredient
  • Composition for alleviating and treating hair loss, hair damage, and skin disease of animal, comprising aptamin c as active ingredient
  • Composition for alleviating and treating hair loss, hair damage, and skin disease of animal, comprising aptamin c as active ingredient

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Experimental program
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Effect test

preparation example

[0044] Preparation example: preparation of the composition of the present invention

[0045]The nucleic acid aptamer sequences used in the present invention are shown in Table 1.

[0046] Table 1

[0047]

[0048] The above nucleic acid aptamers were synthesized at Integrated DNA Technologies (IDT). The composition of the present invention was prepared by mixing the synthesized aptamer and vitamin C (purchased from DMS) in distilled water at normal temperature at the weight ratios described in the respective drawings.

[0049] For reference, the nucleic acid aptamer sequences used in the experiments of the accompanying drawings of the present invention are shown in Table 2.

[0050] Table 2

[0051] sequence 1 figure 1 、 figure 2 、 Figure 4 sequence 2 image 3 、 Figure 5 sequence 3 Figure 6 sequence 4 Figure 7

Embodiment 1

[0052] Example 1: Effect on contact dermatitis

[0053] The composition of the present invention was prepared by mixing 0.2% (w / v) vitamin C (ascorbic acid) and 0.002% (w / v) nucleic acid aptamer combined with the above vitamin C in distilled water.

[0054] Apply the prepared above-mentioned composition to the affected part of the contact skin disease object, such as figure 1 As shown, although the severity of the symptoms differed for each subject, improvement of symptoms recognizable to the naked eye was confirmed within about 5 to 10 days after treatment of the affected parts of all subjects. Also, no side effects were observed in these affected areas.

Embodiment 2

[0055] Example 2: Effect on atopic dermatitis

[0056] The composition of the present invention was prepared by mixing 0.2% (w / v) vitamin C and 0.002% (w / v) nucleic acid aptamer binding to the above vitamin C in distilled water.

[0057] Apply the prepared above-mentioned composition to the affected part of the specific skin disease object, such as Figure 2 to Figure 3 As shown, although the severity of the symptoms differed for each subject, improvement of symptoms recognizable to the naked eye was confirmed within about 5 to 10 days after treatment of the affected parts of all subjects. Also, no side effects were observed in these affected areas.

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PUM

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Abstract

The present invention relates to a composition for alleviating and treating hair loss, hair damage, and a skin disease of an animal, comprising vitamin C and an aptamer binding to vitamin C as active ingredients, and, as alleviation and treatment effects were present in all subjects with hair loss, hair damage, atopic dermatitis, eczema, and contact dermatitis, when treated with the composition of the present invention, the composition can be used as a drug, cosmetic product, etc. for subjects with the conditions.

Description

technical field [0001] The present invention relates to a composition for improving and treating hair loss, hair damage and skin diseases of animals, which contains vitamin C and a nucleic acid aptamer combined with the above-mentioned vitamin C as active ingredients. Background technique [0002] Generally, animals, especially companion animals, have dandruff and keratin in their skin and hair, and are parasitic with lice, hair follicles, and other various bacteria, etc., which not only cause hair damage and hair loss, but also often induce skin diseases. Also, in general, companion animals often emit unpleasant odors that are characteristic of companion animals. Therefore, in order to prevent the disease of companion animals in advance and to remove the peculiar odor of dogs, cleansers or functional body washes containing antiseptic ingredients are used. [0003] However, the sterilizing effect and odor-removing effect of the above-mentioned cleaning agents or functional ...

Claims

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Application Information

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IPC IPC(8): A61K31/375A61K31/7088A61P17/00A61P17/14
CPCA61P17/00A61P17/14A61K31/375C12N15/115C12N2310/16A61K2300/00A61K31/7088
Inventor 孙寅植
Owner (株)纳斯摩仕
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