252 results about "Diseases skin" patented technology

Methods of treating, preventing, correcting and/or managing skin diseases or disorders characterized by overgrowths of the epidermis, keratoses, scleroderma, cutaneous vasculitis, acne or wrinkles are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent. Specific second active ingredients are capable of affecting or inhibiting cell growth or proliferation, removing or improving acne scars, or reducing or correcting wrinkle lines. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

Biocompatible materials are propelled at the skin with sufficient velocity to cause desired resurfacing of skin layers to the desired penetration depth. The materials, such as dry ice or water ice, are harmonious with the human body and thus eliminate foreign body reactions. Various materials may be used in combination, including local anesthetics and vasoconstrictors in solid or liquid form. The biocompatible solid or liquid particles are suspended in a cold carrier fluid and propelled through an insulated delivery system to the surface of the skin. The treatment of diseased skin lesions may be accomplished using the present invention as a drug delivery system.

The present invention provides impedance data having an improved spatial resolution, both with regard to depth and lateral extension, which enables a detection of diseased skin conditions, such a malignant melanoma, at an early stage. Specifically, the present invention is implemented in a probe, medical devices and medical systems including such a probe, and methods using such a probe for measuring electrical impedance of tissue of a subject. A switching circuit is arranged for selectively activate electrode pairs of the probe in accordance with a predetermined activation scheme, the predetermined activation scheme including to activate adjacent electrodes in a successive manner, to gradually scan tissue of the subject at a first tissue depth so as to obtain a sequence of impedance signals from the tissue depth.

A near-permanent skin treatment includes photothermolysis of reddened facial skin to induce ischemia. Reperfusion of the photothermolysis treated skin is inhibited by following with regular applications of phenyl-epinephrine carried in a lotion until vascular necrosis is complete. Alternatively, a temporary treatment for reddened facial skin includes only cosmetic as-needed applications of phenyl-epinephrine carried in lotion to induce vasoconstriction in Rosacea and other similarly embarrassing skin disorders.

The invention relates to a Chinese medicinal composition for treating skin itch and a preparation method thereof. The Chinese medicinal composition mainly comprises the following raw material medicaments: figwort root, root of red-rooted salvia, cortex dictamni, natural indigo, divaricate saposhnikovia root, safflower, peach seed, radix rehmanniae preparata, mint, cicada slough, kudzu-vine root, Mongolian snakegourd root, radix rehmanniae preparata, simpleleaf shrub chastetree fruit, reed rhizome, lalang grass rhizome, common lophatherum herb, gardenia, lightyellow sophora root, ash bark, red paeony root, tree peony bark, sinkiang arnebia root, dahurian patrinia herb, glandularstalk St. paulswort herb, erythrina indica lam, tangerine peel, combined spicebush root, areca peel and the like. The Chinese medicinal composition can be prepared into any common oral preparation by the conventional Chinese medicinal preparation method. The Chinese medicinal composition can obviously improve symptoms such as local or general skin itch caused by various skin diseases, food allergy, medicament allergy and the like. The Chinese medicinal composition has the advantages of exact clinical effects, obvious curative effect, quick response, low cost, basically no toxic or side effects and the like.

The invention relates to a device for the treatment of free-form areas and zones of human or animal skin areas or plant surfaces by means of cold atmospheric-pressure plasma. The core of the device is a specific, preferably gas-permeable, electrode arrangement for generating a dielectrically impeded surface discharge where the earthed electrode is composed of electrically conductive textile material and the high-voltage electrode consists of a thin wire or electrically conductive thread which is sheathed with an insulting layer which has to meet specific requirements. On the basis of the present invention, it is possible to generate, in the area of diseased skin parts of the human body, in direct proximity to the skin surface or to wounds, a flat plasma for the treatment of the diseased areas which is acceptable in respect of the stress on the skin caused by temperature and electric potentials. The advantage of the gas-permeable textile sheet-like structure consists especially in that the arrangement can be placed flexibly onto variously curved surfaces and, in addition, offers the possibility of a gas exchange with the environment and/or the targeted dosing of a specific process gas mixture across the textile material into the active plasma zone.

A multi-ply technical composite, usable in particular for making medical aids, garments and medical articles, includes at least two layers (2, 3), the first of which (2), in contact with the skin, is a cotton fabric (elasticised to a greater or lesser extent) or silk, or fabrics to which chitosan, silver or another antibacterial substance or active constituent is added, and the second, outer layer (3) is constituted by a semipermeable membrane, such as polyurethane between 5 and 80 microns thick, with considerable elasticity in order to ensure the user's comfort. Receptors rechargeable with active constituents are inserted into fabric (2) and protected by the polyurethane membrane.

The present invention relates to method(s) of treating a subject afflicted with a skin disease or condition, the method comprising administering to the subject or patient in need a composition comprising a therapeutically effective amount of a substituted cis or trans-stilbene or a stilbene hybrid. A method of treating or reducing the likelihood of a skin disease or condition in a patient is an additional embodiment of the present invention. Preferred pharmaceutical compositions of the invention include nanoemulsions comprising a therapeutically effective amount of a substituted cis or trans-stilbene or stilbene hybrid and at least one antibiotic.

The present invention discloses a new application of pig skin which can be substituted for human skin and its preparation method. Said preparation method includes the following steps: killing health living while pig with about 50 kg, shaving hair and cleaning pigskin, skinning and chipping to obtain skin sheet, cross-linking with glutaraldehyde, cleaning with balanced salt solution phosphate, soaking it in IM physiological saline containing trypsase, vibrating with Triton-100, more washing it with balanced salt solution phosphate and storing it in refrigerator with 4 deg.C for stand-by. Said invented product has the functional characteristics of two skin substitutes of Integra artificial skin and ADM, so that it not only can be used as temporary wound surface covering material for protecting surface of wound, but also can be used as permanent substitute for dermis for repairing surface of the wound.

The invention discloses a sonchus plant extract used for curing skin diseases and application thereof in preparing medicament for treating skin diseases; the extract is obtained by taking sonchus plants as raw material, extracting by water, filtering and sterilizing the filtrate at high temperature. For water extracting, the temperature is 80-100 DEG C, the period is 1-5 hours, and the extract is filtered with a non-metal filter screen of 200-1,000 meshes. Both the extract of sonchus common sow thistle and the extract of sonchus brachyotus have the functions of antimycotic, antianaphylaxis, antiphlogosis, itch relieving and the like. The extract can be used for curing allergic dermatitis, eczema, skin itch, pimple, scar itch, dermatitis caused by mosquito bite, mycotic infection and other skin diseases. The effective rate and the cure ratio for curing allergic dermatitis, eczema, skin itch, pimple, scar itch, and dermatitis caused by mosquito bite are both 100%, the effective rate for curing dermatophytosis cuased by mycotic is 100% and the cure ration therefor is 70-75%.

The present invention relates to a method for treating dermal inflammation and dermal diseases by local or systemic delivery, in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2 (FPR2).

The invention provides a multimode imaging detection system for skin disease, characterized in that a supercontinuum laser is adopted, different wavelengths for specific skin tissues are selected to acquire hyperspectral and high-resolution confocal imaging, simultaneously the characteristic of deep depth of photoacoustic technique imaging is combined, and system integration of a hyperspectral imaging technique, a reflection type confocal imaging technique and a photoacoustic imaging technique is carried out to form the multimode optical imaging system. The multimode imaging detection system repairs the shortcoming of single-mode imaging in skin diagnosis, and compared with the single-modal technique, the multimode technique provides more complete information, improves the sensibility, accuracy and specificity in skin disease diagnosis, realizes hyperspectral, high-resolution and high-speed multimode optical molecular images for deep level skin disease diagnosis, provides a new technical means for diagnosis and clinical research on skin disease, is favorable for improving the diagnosis level of skin disease, and simultaneously can guide operation on skin disease and provide objective evaluation on medication of skin disease.

The present invention is directed to compositions of nicotinamide derivatives combined with wakame seaweed, wakame extracts, or glycosaminoglycans, and their use in treating skin diseases and disorders.

Methods of treatment and dosage regimes using hydrophobic gel or foam compositions comprising a tetracycline antibiotic for accelorating the return of skin integrity and or in treating or alleviating a disorder including impetigo, acne, rosacea, a skin disease caused by a bacteria or a tetracycline antibiotic responsive disease, wherein the foam composition or gel is administered topically to a target area on a subject having the disorder and wherein the target area comprises an area of skin, or mucosa or an eye.

The present invention describes cosmetic nanotechnology, comprising polymeric nanoparticles containing oil and UV filter, photoprotective compositions comprising polymeric nanoparticles described herein, methods of prevention of diseases of the skin, and processes for the preparation of the polymeric nanoparticles described herein.

The invention discloses a traditional Chinese medicine for treating skin diseases and a preparation method thereof, which pertain to the technical field of Chinese medical pharmaceutical technology. The traditional Chinese medicine comprises 9 to 11 portions of kuh-seng, 9 to 11 portions of cyrtomium fortunei, 9 to 11 portions of honeysuckle, 9 to 11 portions of chrysanthemum, 4 to 6 portions of cicada skins, 4 to 6 portions of fresh licorice, 4 to 6 portions of fructus xanthii, 2 to 4 portions of amoorcorn tree bark and 2 to 4 portions of fructus kochiae, wherein the mixture ratio of the components is weight ratio. The preparation method of the traditional Chinese medicine is vinegar processing method. The traditional Chinese medicine has the functions of clearing heat and drying damp, clearing away heat and toxic materials, cooling blood, dispelling wind and removing heat, removing damp and relieving itching and has great treatment effect on the skin diseases such as whelk, eczema, skin itch, psoriasis, purpura, dermatophytosis, lupus sebaceus and the like, is the good medicine for treating skin diseases and can be used for treating the skin diseases.

The invention provides for methods of detecting and treating diseased tissue, particularly in skin diseases or disorders, such as psoriasis, scleroderma, eczema or atopic dermatitis tissue. The method involves administrating a composition comprising an antibody specific to the diseased tissue to a patient. After administration, the antibody in the composition binds to the exposed cell surface antigen (epitope) and allows the detection and/or disrupts the growth of the diseased tissue. In addition, this invention provides methods of treating psoriasis, scleroderma, eczema or atopic dermatitis by eliciting an immune response in an individual against an antigen which is only exposed to antibody detection in tissues affected by these disorders

The invention relates to a medicine composition for treating skin diseases, in particular to a composition which is prepared with Chinese medicinal materials including radix sophorae flavescentis, rhizoma smilacis glabrae, oriental wormwood, golden cypress, rough gentian, cortex dictamni, purslane, broom cypress fruit, stemona, raw liquorice and optional menthol and borneol. The composition remarkably increases an itch irritating field, can effectively suppress mouse ear swelling, and has high expected safety. In addition, the composition can effectively suppress mouse ear swelling caused by dimethylbenzene, and can effectively suppress rat egg white induced paw swelling.

The present invention relates to the preparation and use of compositions for the treatment of skin disorders itchy and/or infected skin such as impetigo, acne (on face, forehead scalp and on the back of the body) and fungal infection of skin and nails. Whether the infection may be acute or chronic or sub-acute or acute on chronic.

As well as for the promotion of non carrier state of the human beings and animals from some pathogenic bacteria such as staphylococci. The compositions are based on extracts from the plants Cassia tora, Centratherum anthelminticum and/or Melia azadirachta. A variety of other herbal extracts may be included and the composition may take the form of a freeze dried or a spray dried powder or presence of this in a cream or ointment based on Ghee, or in a cream or ointment form developed with any other vehicle, or they may be in a powdered form without spray drying. That spray dried or freeze dried powder may be suspended in a suitable mouth wash or nasal drops. The herbs may be in a powdered form of suitable for preparing decoctions in hot water. Laboratory results are of Specimen Example 2. Specimen Example 1 I have found working on the patients clinically as broad spectrum covering pustules as well as fungal infections.

The present invention is directed to N-methylnicotinamide containing food extracts, and their use in treating lipoprotein abnormalities and skin diseases and disorders.

The invention discloses a loratadine oral quickly-soluble film and a preparation method thereof. By controlling parameters such as particle size of a loratadine drug, proportion of a film-forming material, content of water of a film product and the like, the product dissolution is improved, the bioavailability can be improved, the preparation can effectively prevent and cure such as allergic rhinitis, chronic idiopathic urticaria, allergic asthma, atopic dermatitis and associated symptoms caused by allergy such as skin diseases (eczema, dermatitis, pruritus cutanea), and the drug effect can be sufficiently realized. The loratadine oral quickly-soluble film does not need water, can be rapidly dissolved in the oral cavity and is convenient to take by patients and particularly suitable for the old people and children patients; moreover, the loratadine oral quickly-soluble film has characteristics of high dispersity, rapidness in absorption, fastness in effect, favorability for improving the bioavailability, and the like.

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.