Application of active polysaccharide in preparation of immunity enhancing medicine, pharmaceutical composition or health food
A technology for enhancing immunity and active polysaccharide, applied in the field of biomedicine, can solve the problems of less research on immune regulation and anti-tumor effect, and functional research is limited to in vitro experiments, so as to improve the atrophy of the spleen and thymus, and enhance the body's immunity. force, the effect of promoting secretion
Pending Publication Date: 2021-10-12
QINGDAO UNIV
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[0003] At present, it is reported that a variety of microorganisms such as lactic acid bacteria, yeast, natto and Aureobasidium pullulans can produce active polysaccharides and have good functional activities, but there are few studies on their immune regulation and anti-tumor effects , and its functional studies are mostly limited to in vitro experiments
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[0038] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0039] The experimental methods used in the following examples are conventional methods in the art unless otherwise specified. The materials, reagents and instruments used in the following examples can be obtained from commercial sources unless otherwise specified.
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The invention belongs to the field of biological medicine, and particularly relates to application of active polysaccharide in preparation of immunity enhancing medicine, medicine composition or health food. According to the application, the soft part of Ruditapes philippinarum is taken as a raw material, active polysaccharide capable of remarkably enhancing the immunity of the organism is prepared by screening out bacillus natto as a starting strain through a fermentation method, an immunosuppression mouse model induced by cyclophosphamide is adopted, the immunomodulatory activity of the active polysaccharide is researched, and the action mechanism of the active polysaccharide is preliminarily analyzed; and from two aspects of prevention and treatment effects of immunosuppression, the enhancement effect of the active polysaccharide on the immunity of the organism is verified.
Description
technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to the application of an active polysaccharide in the preparation of immunity-enhancing medicine, pharmaceutical composition or health food. Background technique [0002] Philippine clam, as a sea treasure with the same origin of medicine and food, has gradually become an important raw material for the development of food, medicine and cosmetics due to its low price, wide distribution, high edible and medicinal value and high potential value. In recent years, many scholars have conducted research on the active substances in Philippine clams, and found that amino polysaccharides, glycosaminoglycans and other substances extracted from them have anti-tumor and anti-oxidation effects. my country's Philippine clams are rich in resources, which provide a rich source for the utilization and development of polysaccharides. The realization of the biological activity of polysaccharides...
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IPC IPC(8): A61K31/715A23L33/125A61P37/04C12P19/04C12N1/20C12R1/125
CPCC12P19/04C12N1/20A23L33/125A61K31/715A61P37/04A23V2002/00A23V2200/324A23V2200/30
Inventor 魏玉西宋佳乐
Owner QINGDAO UNIV
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