Extratracheal stent suitable for children and preparation method thereof

Abstract

The invention belongs to the field of medical apparatus and instruments, and particularly relates to an extratracheal stent suitable for children and a preparation method thereof. L-polylactic acid, racemic polylactic acid, a cross-linking agent and an auxiliary agent are blended, a 3D printer is adopted for printing, and then the mixture is placed in a cobalt source irradiation device or an electron accelerator for irradiation cross-linking and sterilization to obtain the extratracheal stent. The L-polylactic acid, the racemic polylactic acid, the cross-linking agent and the auxiliary agent are mixed according to a specific proportion, radiation cross-linking is carried out in the preparation process, the mechanical performance of the prepared extratracheal stent is remarkably enhanced, and the L-polylactic acid and the racemic polylactic acid are compounded, so that the controllable degradation performance of the extratracheal stent can be effectively enhanced; the mechanical strength and biocompatibility of the extratracheal stent are further enhanced by adding the auxiliary agent, the defects of poor mechanical property, poor biocompatibility and uncontrollable biodegradation of the existing stent are effectively overcome, and the clinical requirements of children and other patients at different age stages are better met.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an extratracheal stent suitable for children and a preparation method thereof. Background technique [0002] Tracheomalacia or tracheobronchiomalacia (TBM) is a congenital or acquired defect of the trachea and / or bronchial cartilage. These conditions can be characterized by relaxation of the bronchi or bronchial cartilage, leading to airway obstruction, difficulty breathing, and even death in severe cases. Affecting an estimated 1 in 2,100 children, TBM presents with dyspnea, chronic cough, wheezing, recurrent infections and, in severe cases, life-threatening conditions. Surgical intervention may be required for adults and infants with severe forms of TBM that do not respond to medical therapy or have life-threatening symptoms. Severe cases can result in death or require a tracheostomy and ventilation for 2-3 years, placing a burden on the child and family. Current treatment tec...

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