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Traditional Chinese medicine composition for treating lymphoma and preparation method and application thereof

A composition and lymphoma technology, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc., can solve the problems that have not been reported, and achieve the effect of promoting apoptosis

Active Publication Date: 2022-01-14
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But a kind of Chinese medicine composition for the treatment of lymphoma of the present invention and its preparation method and application have not yet been reported

Method used

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  • Traditional Chinese medicine composition for treating lymphoma and preparation method and application thereof
  • Traditional Chinese medicine composition for treating lymphoma and preparation method and application thereof
  • Traditional Chinese medicine composition for treating lymphoma and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0040] The preparation of embodiment 1 Chinese medicine composition of the present invention (one)

[0041] Weigh 10 parts of Prunella vulgaris, 3 parts of Shanzi mushroom, 9 parts of Shi Jianchuan, 9 parts of Zihua Diding, 3 parts of Zihuazizi, 25 parts of raw coix seed, 9 parts of trigonum, 9 parts of curcuma, 10 parts of bone skin, 3 parts of Patrinia, 3 parts of turtle shell, 3 parts of Anemarrhena, 3 parts of tangerine peel, 3 parts of ginger pinellia, 5 parts of white poria cocos, 3 parts of licorice, and 0.05 part of realgar.

Embodiment 2

[0042] The preparation of embodiment 2 Chinese medicine composition of the present invention (two)

[0043] Weigh 10 parts of Prunella vulgaris, 3 parts of Shanzi mushroom, 9 parts of Shi Jianchuan, 9 parts of Zihua Diding, 3 parts of Zihuazizi, 25 parts of raw coix seed, 9 parts of trigonum, 9 parts of curcuma, 10 parts of bone skin, 3 parts of Patrinia, 3 parts of turtle shell, 3 parts of Anemarrhena, 3 parts of tangerine peel, 3 parts of ginger pinellia, 5 parts of white poria cocos, and 3 parts of licorice.

Embodiment 3

[0044] The preparation of embodiment 3 Chinese medicine composition of the present invention (three)

[0045] Weigh 30 parts of Prunella vulgaris, 18 parts of Shanzi mushroom, 30 parts of Shi Jianchuan, 30 parts of Zihua Diding, 18 parts of Zihua Diding, 35 parts of raw coix seed, 30 parts of trigonum, 30 parts of curcuma, 30 parts of bone skin, 18 parts of Patrinia, 18 parts of turtle shell, 18 parts of Anemarrhena, 18 parts of tangerine peel, 18 parts of ginger pinellia, 30 parts of white poria cocos, 9 parts of licorice, and 0.1 part of realgar.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating lymphoma and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following medicines in parts by weight: 10-30 parts of spica prunellae, 3-18 parts of edible tulip, 9-30 parts of salvia chinensis, 9-30 parts of herba violae, 3-18 parts of semen impatientis, 25-35 parts of raw semen coicis, 9-30 parts of rhizoma sparganii, 9-30 parts of curcuma zedoary, 10-30 parts of cortex lycii radicis, 3-18 parts of herba patriniae, 3-18 parts of turtle shell, 3-18 parts of rhizoma anemarrhenae, 3-18 parts of pericarpium citri reticulatae, 3-18 parts of ginger processed pinellia, 5-30 parts of white poria cocos and 3-9 parts of liquorice. The traditional Chinese medicine composition further comprises the following raw material medicine in parts by weight: 0.05-0.1 part of realgar. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition can effectively inhibit proliferation and growth of lymphoma cells Raji cells and Jeko-1 cells, and time and concentration dependence is shown. In addition, the detoxification and tumor elimination formula can also up-regulate expression of pro-apoptotic protein of lymphoma cells and inhibit expression of anti-apoptotic protein of the lymphoma cells at the same time, so that obvious apoptotic bodies are formed, apoptosis of the lymphoma cells is effectively promoted, and the detoxification and tumor elimination formula is concentration-dependent.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating lymphoma and its preparation method and application. Background technique [0002] Lymphoma is a malignant tumor originating from the lymphatic hematopoietic system. It is mainly manifested as painless lymphadenopathy, hepatosplenomegaly, and various tissues and organs of the whole body can be involved, accompanied by systemic symptoms such as fever, night sweats, weight loss, and itching. [0003] According to the tumor cells, it is divided into two types: non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL). Pathological features In Hodgkin's lymphoma, the tumor tissue contains lymphocytes, eosinophils, plasma cells and specific Reed-Steinberg cells, and HL is divided into nodular lymphoid-rich Cellular and classical, the latter including lymphocyte predominant, nodular sclerosis, mix...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K33/36A61K35/586
CPCA61K36/536A61K36/898A61K36/537A61K36/86A61K36/185A61K36/8994A61K36/902A61K36/9066A61K36/815A61K36/84A61K35/586A61K36/8964A61K36/752A61K36/8888A61K36/076A61K36/484A61K33/36A61P35/00A61K2236/331A61K2300/00Y02A50/30
Inventor 胡琦陆嘉惠鲍计章张红玉邓剑青刘敏江雯雯任建业陈懿榕冯晓卫胡明
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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