Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of composition in preparation of medicine for treating or preventing depression

A composition and depression technology, applied in the direction of drug combination, pharmaceutical formula, anhydride/acid/halide active ingredient, etc.

Active Publication Date: 2022-05-13
TIANJIN ZHONGXIN PHARMA GRP CO LTD +1
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention studies the properties of ferulic acid and ligustilide individually and in combination, and finds that the two have a vasodilation effect respectively, and the combination of the two has a synergistic effect, which has not been reported in the existing literature

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of composition in preparation of medicine for treating or preventing depression
  • Application of composition in preparation of medicine for treating or preventing depression
  • Application of composition in preparation of medicine for treating or preventing depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0142] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0143] Ferulic acid: Z-ligustilide = 1:4.

[0144] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

Embodiment 2

[0146] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0147] Ferulic acid: Z-ligustilide = 1:5

[0148] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

Embodiment 3

[0150] The composition contains ferulic acid and Z-ligustilide, and the weight ratio of the two is:

[0151] Ferulic acid: Z-ligustilide = 1:6

[0152] The composition is obtained by mixing ferulic acid and Z-ligustilide, or by mixing the extract of traditional Chinese medicine containing ferulic acid and the extract of traditional Chinese medicine containing Z-ligustilide, or by co-extracting Angelica sinensis and Rhizoma Chuanxiong get.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
weightaaaaaaaaaa
Login to View More

Abstract

The invention relates to application of a pharmaceutical composition. The application comprises treatment or prevention of depression. The composition contains ferulic acid and ligustilide, the weight ratio of ferulic acid to Z-ligustilide is 1: (4-10), or ferulic acid to Z-ligustilide is 1: 4, or ferulic acid to Z-ligustilide is 1: 10, or ferulic acid to Z-ligustilide is 1: 9.43, and the composition can also contain senkyunolide I, (-)-apigenyl lactide and senkyunolide H, all the components are as follows in percentage by weight;

Description

technical field [0001] The present invention relates to a kind of composition and its pharmaceutical preparation, especially a kind of drop pill preparation, described preparation has the effect of treating headache, dizziness, apoplexy, blurred vision, forgetfulness, insomnia, especially has the effect of treating or preventing depression Effect. Background technique [0002] It is known that many traditional Chinese medicines have the effects of regulating qi and activating blood circulation, removing blood stasis and relieving pain. As the disclosed dropping pill of State Food and Drug Administration National Drug Standard YBZ00432005-2009Z. [0003] Chinese patent 97105810.5 discloses a dripping pill containing Rhizoma Chuanxiong and Angelica ether extracts and a preparation method thereof. The preparation process disclosed in its embodiment is as follows: take 50% each of Rhizoma Chuanxiong and Angelica coarse powder, mix evenly, use 95% ethanol as solvent, completely...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/365A61P25/24A61K31/192A61K31/201A61K31/20
CPCA61K31/365A61K31/192A61P25/24A61K31/201A61K31/20A61K2300/00
Inventor 周鸿刘丹刘彤王金磊
Owner TIANJIN ZHONGXIN PHARMA GRP CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com