Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Methods for promoting oestrus in female mammals

A technology for mammals and females, applied in the fields of animal medicine and reproductive medicine, can solve problems such as fluctuations in synchronous ovulation effects, influence on female animals, and reduced response ability, achieve stable Kp structure and quality, increase estrus rate and conception rate, and reduce the number of times and the effect of quantity

Pending Publication Date: 2022-05-20
BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limited source of PMSG, its quality is affected by many factors such as mare's gestation time, body size, parity, exercise, body condition, genetics, etc., resulting in unstable quality of PMSG between batches
In addition, PMSG is an exogenous protein, long-term use can easily cause the body to produce antibodies, thereby reducing the body's ability to respond to PMSG and affecting the effect of PMSG on promoting follicle development
At present, the molecular structure of GnRH that promotes synchronous ovulation licensed in China is unstable, and the effect of synchronous ovulation fluctuates greatly after use.
In addition, in the routine timed insemination procedure, the dam needs two intramuscular injections of relevant hormones within 5 days. This operation puts a lot of stress on the dam and can easily cause the secretion of reproductive hormones in the dam to be disturbed, thereby affecting the follicular development of the dam, pregnancy and even lead to Serious consequences of follicular cysts

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Methods for promoting oestrus in female mammals
  • Methods for promoting oestrus in female mammals
  • Methods for promoting oestrus in female mammals

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Weaned Large White × Landrace binary cross weaning sows that were healthy and had similar litter performance were injected with normal saline, 0.5 mg Kp, 1 mg Kp and 1000 IU PMSG 24 hours after weaning, and 3 sows were treated in each group. On the day of weaning, the 1st day, the 2nd day, the 3rd day and the 4th day after weaning, the follicular growth and development of the sows in each treatment group were detected by B-ultrasound abdominal ultrasound, and the test results were as follows: figure 1 As shown, sows treated with Kp can promote follicular growth.

Embodiment 2

[0034] Weaned Large White × Landrace binary cross weaned sows that were healthy and had similar litter performance were selected. The day of weaning was recorded as "Day 0", and the weaning time was 16:00.

[0035] Sows in the experimental group were randomly divided into Kp10 group, Kp500 group, and Kp1000 group. 24h, 48h, 72h, and 96h after weaning, 10 μg, 500 μg, and 1000 μg of Kp (Genscript, USA) were injected intramuscularly, respectively, and selected after an interval of 16 and 24 hours. The semen required for breeding is artificially inseminated. The insemination volume is 80ml, and the effective sperm count is about 3 billion.

[0036] Sows in the control group were injected intramuscularly with 1000 IU PMSG (trade name: hemotropin, Ningbo Sansheng Biotechnology Co., Ltd.) 24 hours after weaning (n=102 heads), and intramuscularly injected GnRH 100 μg at intervals of 72 hours, and the intervals were 16 hours and 24 hours respectively. Artificial insemination. 96 hours...

Embodiment 3

[0046] Weaned Large White × Landrace binary cross weaned sows that were healthy and had similar litter performance were selected. The day of weaning was recorded as "Day 0", and the weaning time was 16:00.

[0047] Sows in the experimental group were randomly divided into Kp10 group (n=47 heads), Kp500 group (n=50 heads), Kp1000 group (n=50 heads). Inject 10, 500, and 1000 μg Kp (Genscript, USA), and inject 100 μg GnRH (trade name: Gonadorelin, Ningbo Sansheng Biotechnology Co., Ltd.) intramuscularly at intervals of 72 hours, and select them after intervals of 16 and 24 hours. The semen that meets the breeding requirements is artificially inseminated, the insemination volume is 80ml, and the effective sperm count is about 3 billion.

[0048] The sows in the control group were injected intramuscularly with 1000 IU PMSG (trade name: hemotropin, Ningbo Sansheng Biotechnology Co., Ltd.) 24 hours after weaning (n=102 heads), and intramuscularly injected 100 μg of GnRH at intervals ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a method for promoting reproductive performance of female mammals, follicle development of the female mammals can be effectively promoted and oestrus can be promoted by applying Kp at a proper dosage at a proper time, the Kp structure and quality are stable, synchronous ovulation of female animals can be promoted by applying Kp in a timed insemination technology, and the reproductive performance of the female mammals can be promoted. The oestrus rate and conception rate of the female livestock are effectively improved, the missed mating rate of the recessive oestrus female livestock is reduced, the reproductive performance of the female livestock is remarkably improved, and meanwhile the welfare of the female livestock is effectively improved.

Description

technical field [0001] The invention belongs to the technical fields of veterinary medicine and reproductive medicine, and in particular relates to a product and a method for promoting reproductive performance of female mammals. Background technique [0002] In the animal husbandry industry, the reproductive performance of animals is directly related to the production and breeding benefits. During the breeding process of animals, problems such as unobvious estrus symptoms, irregular estrus and ovulation, and delayed ovulation will lead to reduced conception rates, prolonged birth intervals, and The decline in reproductive rate has affected the production management and economic benefits of large-scale farming. It is an important measure to increase the reproductive rate to carry out drug treatment when the female animal reaches the childbearing age or within a certain period of time after the female animal gives birth to promote the reproductive performance of the female ani...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/00A61D19/02A01K67/02
CPCA61D7/00A61D19/027A01K67/02
Inventor 秦玉圣刘彦田见晖白佳桦宋玉清许晓玲冯涛肖霖力
Owner BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com