Integral oxygen supply and agitation equip

An agitation device and oxygen supply technology, applied in biochemical cleaning devices, enzymology/microbiology devices, biochemical instruments, etc., can solve the problems that may not meet the requirements of agitation design and operation, difficult to inhale gas sterilization and purification, impeller It is difficult to achieve the mixing effect and other problems, to achieve the effect of easy monitoring and control, convenient installation and maintenance, and saving operating expenses

Inactive Publication Date: 2005-11-23
绿意得生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] 1) Only air can be supplied to the bioreactor, and when the culture medium is required to have a high concentration of dissolved oxygen, the device is difficult to meet its needs;
[0010] 2) It is not easy to sterilize and purify the inhaled gas, and it is easy to cause the culture solution to contaminate miscellaneous bacteria;
[0011] 3) It is necessary to ensure that the impeller is above a certain speed in order to form enough negative pressure to inhale air; however, the impeller speed at this time is often difficult to achieve the ideal stirring effect;
[0012] 4) The shape design and speed selection of the impeller are mainly for suction, which may not be able to meet the design and operation requirements for stirring;
[0013] 5) The open air guide pipe or impeller air intake pipe is easily blocked locally, resulting in difficulty in air intake;
[0014] 6) Due to the passive air supply method, it is difficult to measure and monitor the intake air volume, which is not conducive to process control

Method used

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  • Integral oxygen supply and agitation equip
  • Integral oxygen supply and agitation equip
  • Integral oxygen supply and agitation equip

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] The present invention has designed a set of integrated oxygen supply stirring device, and it is made up of three parts, as image 3 shown.

[0050] 1) Transmission system

[0051] Transmission system is made up of motor 13, frame 14, axle sleeve 15. Axle sleeve 15 connects stirring shaft 18 and motor drive shaft, and can be disassembled here during maintenance. The function of the transmission system is to provide stirring power. According to different needs, the transmission system can be installed on the upper flange of the bioreactor or the bottom of the tank.

[0052] 2) Air guide system

[0053] The air guide system is made up of intake pipe 16, air guide seat assembly 17 and air delivery stirring shaft 18. The outer port of the air intake pipe 16 is used to connect with the air supply pipeline, and the inner end leads into the air chamber 20 of the air guiding seat. Stirring shaft 18 is a hollow shaft passing through air guide seat air chamber 20, the part w...

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Abstract

An integrated oxygen-supplying and stirring apparatus is composed of drive system, oxygen delivering system and stirring assemblage. Its advantages are synchronous oxygen supplying and stirring, simple structure, high efficiency and low energy consumption.

Description

technical field [0001] The invention relates to an oxygen supply and stirring device for a bioreactor, in particular to a device integrating the functions of oxygen supply and stirring. Background technique [0002] In bioreactors used to cultivate cells, microorganisms, etc., the oxygen supply aeration device and the stirring device have always been the core devices. The efficiency of oxygen supply and stirring will directly affect the success, progress and time of the cultivation. [0003] According to the traditional theory, in any aerobic fermentation device or bioreactor system, oxygen supply and agitation are two independent systems. See Chinese patents 95113902.9 and 91217060.3. [0004] The oxygen supply system generally consists of a gas supply source, a ventilation pipe, and a gas distributor. Common gas supply sources include: blower, air compressor, air / oxygen cylinder or oxygen generator; the gas distributor can be made into different shapes such as tube or di...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): C12M1/06
CPCC12M41/42C12M27/04
Inventor王晓军
Owner绿意得生物科技有限公司