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Medicine for treating mammary cancer recurrence and metastasis and the preparation thereof

A technology for recurrence, metastasis, and breast cancer, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of poor prognosis and insensitivity of endocrine therapy for breast cancer patients

Active Publication Date: 2006-10-25
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Estrogen receptor-positive breast cancer patients have a better prognosis and are sensitive to endocrine therapy. Postoperative endocrine therapy drugs can prevent tumor recurrence and metastasis, but estrogen receptor-negative breast cancer patients have a poorer prognosis and are not sensitive to endocrine therapy. Sensitive, there is still no effective anti-relapse and metastasis drug like endocrine therapy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh 1000 grams of Lu Fengfang, 600 grams of Shan Arthiasis, 1000 grams of Zedoary Curcuma, 1000 grams of August Zha, 3000 grams of Raw Coix Seed, add 4 times the amount of water, decoct for 1.5 hours, filter, and concentrate to a relative density of about 1.35 (80 ℃), adding appropriate amount of dextrin, granulating (14-16 mesh), vacuum drying (80 ℃), sub-packaging to obtain.

Embodiment 2

[0039] Weigh 1,000 grams of Lufengfang, 900 grams of Arthia chinensis, 2,000 grams of Curcuma, 2,000 grams of August Zha, 3,000 grams of Raw Coix Seed, add 6 times the amount of 75% ethanol, reflux extraction twice, each time for 1.5 hours, filter, and combine The filtrate is recovered from ethanol until there is no alcohol smell, concentrated to a clear paste with a relative density of about 1.35 (80°C), adding an appropriate amount of dextrin, granulating (14-16 mesh), vacuum drying (80°C), and packaging to obtain.

Embodiment 3

[0041] Weigh 1,000 grams of Lufengfang, 1,500 grams of Arrowhead Arrowhead, 3,000 grams of Zedoary Curcuma, 3,000 grams of August Zha, 3,000 grams of Raw Coix Seed, add 8 times the amount of 90% ethanol, reflux extraction three times, each time for 1.5 hours, filter, and combine the filtrates , recover ethanol until there is no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack to obtain.

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PUM

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Abstract

The invention provides a medicament for treating galactophore cancer recrudescence and transfer, wherein the medicament is prepared from the following raw materials wherein the microcapsule comprises the following raw materials (by weight portion), wasp's nest 10-20 parts, Star of Bethlehem 6-15 parts, zedoary 10-30 parts, bayuezha 9-30 parts, raw rice sseds 10-30 parts.

Description

technical field [0001] The invention relates to a medicine for treating recurrence and metastasis of breast cancer and a preparation method of the medicine. Background technique [0002] Breast cancer is a malignant tumor that seriously threatens women's health, and its incidence rate ranks first among female malignant tumors. Infiltration and metastasis are the basic characteristics of malignant tumors. Radiotherapy and chemotherapy can effectively reduce the recurrence and metastasis rate of tumors, but the side effects are obvious, especially after radiotherapy and chemotherapy, the treatment methods of western medicine are still relatively limited. A large number of studies have proved that the biological behavior of breast cancer with different estrogen receptor status is very different. Estrogen receptor-positive breast cancer patients have a better prognosis and are sensitive to endocrine therapy. Postoperative endocrine therapy drugs can prevent tumor recurrence an...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/898A61K36/185A61K35/64A61P35/00
Inventor 刘胜陆德铭唐汉钧
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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