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Plant extractive for treating cancer

A plant extract, cancer technology, applied in the direction of drug combination, medical preparations containing active ingredients, peptide/protein components, etc., can solve the problems of no relevant reports on the medical use of swainsonine, to improve immunity, inhibit effect on tumor cells

Inactive Publication Date: 2004-04-07
葛鹏斌
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  • Abstract
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Problems solved by technology

However, there is no relevant report on the medical use of swainsonine, especially in the treatment of cancer.

Method used

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  • Plant extractive for treating cancer
  • Plant extractive for treating cancer

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Embodiment Construction

[0014] The plant extract in the present invention is swainsonine, which is a plant extract of the genus Oxytropis leguminosae. Swainsonine can be used in combination with the immunomodulator poly IC (poly IC) interleukin (IL-2) or in combination.

[0015] (1) Antitumor activity of swainsonine

[0016] 1. The effect of swainsonine on the survival time of tumor-carrying animals

[0017] An important question in the treatment of cancer with swainsonine is whether the inhibition of tumor metastasis can prolong the survival time of the host. Trials have been performed with swainsonine in combination with the immunomodulators poly-IC (poly IC) or interleukin (IL-2). When swainsonine is used continuously alone, in injection B 16 -BL 16 There was no apparent difference between animals with melanoma cells and untreated animals. However, when swainsonin was combined with poly IC or IL-2, the survival time was significantly different. For example, at 65 days after tumor cell inject...

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Abstract

The present invention relates to one kind of plant extractive for treating cancer, and the plant extractive can suppress tumor cell and raise body's immunity obviously. The plant extractive of the present invention is swainsonine extracted from thinleaf crazyweed as one kind of leguminous plant. Swainsonine is used through cooperating with poly IC or IL-2.

Description

1. Technical field: [0001] The present invention relates to a plant extract for treating cancer. 2. Background technology: [0002] my country is rich in Oxytopis plant resources of leguminous family, which are mainly distributed in Inner Mongolia, Ningxia, Gansu, Qinghai, Xinjiang, Tibet, Shaanxi, Sichuan and other provinces and regions. Among them, the area of ​​Oxytopis in Inner Mongolia is 3.266 million hectares, accounting for Its grassland area is 4.14%, the area of ​​Oxytropis chinensis in Qinghai is 2 million hectares, the area of ​​Oxytropis chinensis accounts for 5.13% of its grassland area, the area of ​​Oxytropis chinensis in Tibet is 2.209 million hectares, the area of ​​Oxytropis chinensis accounts for 2.68% of its grassland area, and the area of ​​Oxytropis chinensis in Gansu is 1.412 million hectares , the area of ​​Oxytropis accounted for 7.89% of its grassland area. According to incomplete statistics, the national distribution area exceeds 11 million hectare...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/353A61K31/787A61K38/20A61P35/00
Inventor 曹光荣赵宝玉童德文葛鹏斌
Owner 葛鹏斌
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