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Chinese medicine cataplasm matrix and preparing technique thereof

A poultice and matrix technology, applied in the field of traditional Chinese medicine poultice matrix and its preparation technology, can solve the problems of easy irritation, uncontrollable viscosity, easy allergy and the like, and achieves the effects of increasing curative effect, not polluting clothes, and high curative effect

Inactive Publication Date: 2004-09-15
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The adhesive plasters, breathable adhesive plasters, "capsicum diced" type cataplasms and other patches and traditional plasters produced by many domestic manufacturers all have small drug capacity, poor transdermal effect, easy irritation, allergy, and inability to relieve pain. Disadvantages such as drug release, inability to repeatedly peel off, uncontrollable viscosity, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Component Quantity (g / paste)

[0040] Polyacrylic acid 0.45

[0041] Glycerin 1.80

[0042] Triethanolamine 0.27

[0043] Magnesium hydroxide 0.054

[0044] Polyvinylpyrrolidone 0.108

[0045] Azone 0.162

[0046] water 7.4

[0047] Ointment 1.649

Embodiment 2

[0049] Component Quantity (g / paste)

[0050] Polyacrylic acid 0.51

[0051] Glycerin 1.92

[0052] Triethanolamine 0.27

[0053] Magnesium hydroxide 0.063

[0054] Polyvinylpyrrolidone 0.105

[0055] Azone 0.162

[0056] water 7.6

[0057] Ointment 1.426

[0058] The preparation technology of described Chinese medicine cataplasm matrix is ​​as follows:

[0059] Component A: Add 15-60 parts of water into the mixer, turn on the mixer, quickly and evenly add polyacrylic acid, and continue to stir until it becomes a transparent colloid.

[0060] Component B: Mix triethanolamine and 5-20 parts of water.

[0061] Component C: Grind magnesium hydroxide and mix it with glycerin.

[0062] Component D: Dissolve polyvinylpyrrolidone in water to make a 50% aqueous solution, and mix it with azone.

[0063] Mix component A and component B, and stir evenly, then add component C and component D respectively, and stir evenly to obtain the cataplasm matrix.

[0064] Among them, polyacr...

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PUM

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Abstract

The present invention relates to a Chinese medicine emplastrum matrix which can be added into Chinese medicine extract and its preparation technique. Said matrix is made up by mixing polyacrylic acid, glycerine, triethanolamine, magnesium hydroxide, polyvinylpyrrolidone, azone and water. Said matrix has large medicine-carrying quantity, unique slowly-releasing process, strong transdermal effect, good breathing property and good affinity with various medicines and skin. Said invented matrix is suitable for making Chinese medicine emplastrum, and is an ideal transdermal administration transferring platform.

Description

technical field [0001] The invention relates to a material used for an externally used traditional Chinese medicine plaster, in particular to a matrix of a traditional Chinese medicine cataplasm and its preparation technology. Background technique [0002] Medicine is a sunrise industry in the 21st century, and traditional Chinese medicine is an industry with obvious comparative advantages in my country and has strong international competitiveness. It is reported that the sales of transdermal preparations worldwide will rise from US$1.6 billion in 1993 to US$9.1 billion in 2003, ranking first among all dosage forms with an annual growth rate of 17.8%. The market demand and its growth are very considerable. The World Health Organization predicts that in the next 2 to 3 years, more than 30% of oral drugs will need to be transdermally administered. [0003] The adhesive plasters, breathable adhesive plasters, "capsicum diced" type cataplasms and other patches and traditional p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/32
Inventor 任建国郭建文
Owner XIAN CHIHO PHARMA
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