Use of anticholinergic M3-type receptor antibody determination for diagonsing sicca syndrome

A cholinergic and receptor technology, applied in the field of anticholinergic M3 receptor antibody determination in the diagnosis of Sjogren's syndrome, can solve problems such as poor medical compliance, delayed diagnosis, and lost treatment opportunities
CN1896101AInactive Publication Date: 2007-01-17PEOPLES HOSPITAL PEKING UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
PEOPLES HOSPITAL PEKING UNIV
Publication Date
2007-01-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

Determination of anticholinergic M3 receptor and antibody is used to diagnose sicca syndrome. It has excellent sensitivity and specificity.
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Description

[0001] The invention relates to the application of the anti-cholinergic M3 receptor antibody as an antigen in detecting Sjögren's syndrome and other diseases. 1. Technical background

[0002] Sjogren's syndrome (SS) is a systemic autoimmune disease characterized by invading exocrine glands such as lacrimal glands and salivary glands. The most common clinical manifestations of the disease are dry eyes and dry mouth, and can involve the lungs, kidneys, lymphatic system, blood vessels and liver and other organs. The disease has no obvious regional distribution difference, and can occur at any age, with 40-60 years old, especially postmenopausal women in the majority, and the ratio of male to female is 1:9. The prevalence rate in my country is 0.77%, and the prevalence rate in the elderly population is as high as 4%. There are nearly 10 million patients in the whole country.

[0003] In recent years, people have conducted a lot of research on the etiology and pathogenesis of Sjog...

Claims

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