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Polypeptide, detector containing the polypeptide, and detection kit containing the polypeptide

A technology for detection kits and devices, applied in the field of peptides, can solve problems such as differentiation

Inactive Publication Date: 2014-06-25
SUZHOU SJ BIOMATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is difficult to distinguish it from other autoimmune diseases such as connective tissue diseases only by the judgment of symptoms. Therefore, it is necessary to use the detection of specific autoantibodies in serum to assist the diagnosis

Method used

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  • Polypeptide, detector containing the polypeptide, and detection kit containing the polypeptide
  • Polypeptide, detector containing the polypeptide, and detection kit containing the polypeptide
  • Polypeptide, detector containing the polypeptide, and detection kit containing the polypeptide

Examples

Experimental program
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Effect test

Embodiment

[0072] 1.30 Preparation and Confirmation of Peptides

[0073] The 20 peptide used in the examples has the amino acid sequence shown in SEQ ID NO: 1 and was synthesized by Jill Biochemical (Shanghai) Co., Ltd. For the characterization map of the peptide, see figure 2 and image 3 , it was confirmed that the polypeptide was synthesized.

[0074]

[0075] 2. Fabrication of Detection Devices

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Abstract

The invention relates to a polypeptide, a detector containing the polypeptide, and a detection kit containing the polypeptide. The polypeptide is composed of an amino acid sequence represented by the SEQ ID No.1. The polypeptide, the detector containing the polypeptide, and the detection kit containing the polypeptide are useful in the diagnosis of sicca syndrome.

Description

technical field [0001] The invention mainly relates to a polypeptide, a detection device and a detection kit containing the polypeptide, and belongs to the field of biotechnology. Background technique [0002] Sjögren syndrome (SS) is a chronic autoimmune disease mainly invading lacrimal glands, salivary glands and other exocrine glands, also known as autoimmune exocrine gland disease. The main manifestations are keratoconjunctivitis sicca, xerostomia, or other rheumatic diseases associated with rheumatoid arthritis, which can involve other systems such as the respiratory system, digestive system, urinary system, blood system, nervous system, muscles, and joints Cause damage to multiple systems and organs. [0003] Sjögren's syndrome is a global disease, more than 90% are women, and the age of onset is mostly middle-aged and elderly people aged 40-60, and children are less. Due to the lack of uniform diagnostic criteria so far, the prevalence of the disease is very inaccur...

Claims

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Application Information

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IPC IPC(8): C07K7/08C07K16/00C12N15/11C12N15/63C12N1/15C12N1/19C12N1/21C12N5/10G01N33/68
Inventor 李钟马雄明章为江
Owner SUZHOU SJ BIOMATERIALS
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