Endovascular device for sensing and or stimulating tissue

a technology of endovascular devices and tissue, applied in the field of medical devices, can solve the problems of limiting mobility, function and independence, requiring daily application, prone to noise and movement related artefacts, etc., and achieve the effect of facilitating electrical coupling of the electrode element(s)

Active Publication Date: 2020-01-09
UNIVERSITY OF MELBOURNE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention is a medical device that can be implanted into a blood vessel of an animal. It includes a stent that can be collapsed for insertion and expanded to resiliently bear against the wall of the vessel. The stent carries one or more electrodes that can stimulate and sense activity in the surrounding tissue and fluid. The stent can be a conventionally designed medical stent or any mechanical framework or scaffolding that positions the electrodes within the body and facilitates electrical coupling. The invention allows for the treatment of various medical conditions within the blood vessel system.

Problems solved by technology

In many of these patients, however, the portion of the brain responsible for movement remains intact, and it is disease and trauma to the spinal cord, nerves and muscles that limit mobility, function and independence.
While this method has been highly successful for amputees by re-innervating forearm nerves into abdominal muscles which control a bionic arm, the restored function greatly depends on the site of damage or condition, with people paralyzed by brainstem or high cervical injuries only able to achieve minor functional improvement.
While cortical measurements performed with electrodes placed on the scalp enable non-invasive neuronal measurements, they require daily application and are prone to noise and movement related artefacts.
These methods, however, require invasive surgery and carry a relatively high risk of complication, which can involve infections and bleeding.
Furthermore, craniotomies are limited in access to the central nervous system, with many motor and sensory cortex areas hidden and inaccessible within cortical folds.
These approaches are restricted in position and cannot be relocated once implanted and are subject to signal deterioration due to glial scar formation surrounding penetrating electrodes.

Method used

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  • Endovascular device for sensing and or stimulating tissue
  • Endovascular device for sensing and or stimulating tissue
  • Endovascular device for sensing and or stimulating tissue

Examples

Experimental program
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Embodiment Construction

[0089]The system 10 shown in FIGS. 1 to 4 includes: 1) a medical device 100 designed for placement within a vessel 103 of an animal or human 110 to stimulate and / or sense the activity of media (tissue and fluids) proximal (adjacent or touching) to the device 100, whether this be located inside or outside the vessel 103; 2) a control unit 12 (also referred to as a connector block and telemetry system) adapted for communication with the device; 3) a communication conduit 14 for facilitating communications between the device 100 and the control unit 12; and 4) apparatus 16 coupleable to the animal or human 110, the apparatus 16 adapted for communication with the control unit.

[0090]The control unit 12 can be adapted to perform the steps of: (a) receiving data from the device 100 representing activity of media proximal to the device 100; (b) generating control signals for the apparatus 16; and (c) sending the control signals to the apparatus 16. In some variations, the system includes co...

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Abstract

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and / or sensing activity of media proximal to the device, wherein the media includes tissue and / or fluid.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims priority to U.S. Provisional Application No. 62 / 486,851 filed Apr. 18, 2017 which is incorporated herein by reference in its entirety for all purposes.TECHNICAL FIELD OF THE INVENTION[0002]The present invention relates to a medical device for implantation into a blood vessel of an animal.BACKGROUND OF THE INVENTION[0003]Any discussion of document, devices, acts or knowledge in this specification is included to explain the context of the invention. It should not be taken as an admission that any of the material forms a part of the prior art base or the common general knowledge in the relevant art in Australia or elsewhere on or before the priority date of the disclosure and broad consistory statements herein.[0004]In the United States alone, nearly two million people suffer from various neuromuscular disorders where control of limbs is severely impaired. In many of these patients, however, the portion of the brain re...

Claims

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Application Information

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Patent Type & AuthorityApplications(United States)
IPC IPC(8): A61F2/06A61B5/042A61B5/04A61B5/0478A61B5/296
CPCA61B5/042A61B5/0478A61F2/06A61B5/0215A61B5/04001A61F2/90A61F2230/0067A61F2250/0001A61B5/6862A61B5/4052A61B5/4064A61B5/4836A61B2505/09A61B5/7207A61N1/0531A61N1/0539A61B5/24A61B5/291A61B5/6877A61F2/72A61N1/0529A61N1/36103A61N1/36128A61N1/37211A61N1/37205A61F4/00A61F2/88A61B5/283
InventorOPIE, NICHOLAS LACHLANOXLEY, THOMAS JAMESRIND, GIL SIMONRONAYNE, STEPHEN MICHAELJOHN, SAM EMMANUEL
OwnerUNIVERSITY OF MELBOURNE