The invention discloses a pesticide combination containing SYP-9625. The effective active ingredients include the active ingredient A and the active ingredient B, wherein the active ingredient A is the SYP-9625, the active ingredient B is one of the following compounds including hexythiazox, spirodiclofen, clofentezine, fenbutatin oxide, etoxazole, bromopropylate, flutenzine, cyflumetofen, fluacrypyrim and pyriminostrobin, and the weight ratio of the active ingredient A to the active ingredient B is 1:80-80:1. The combination has the synergistic effect to various pests endangering agricultural production, the quantity of pesticides is reduced, pesticide residues on plants are reduced, pollution to the environment is relieved, the combination is safe to human beings and livestock and has good environmental compatibility, and pests are not liable to have drug resistance.