3 results about "Stent thrombosis" patented technology

The application relates to the application of lycorine hydrochloride in the preparation of a medicine for inhibiting the proliferation of a neointimal in a blood vessel. Lycorine hydrochloride has the effect of inhibiting the proliferation of a neointimal in a blood vessel, and the effect is mainly realized by inhibiting the proliferation and migration of vascular smooth muscle cells. In the body, the results show that lycorine hydrochloride can significantly inhibit the intimal proliferation caused by left common carotid artery ligation, and in vitro experiments prove that lycorine hydrochloride can intervene in the proliferation, migration and phenotype transformation of VSMCs induced by PDGF-BB. Lycorine hydrochloride inhibits the proliferation, migration and phenotype transformation of VSMCs induced by PDGF-BB, and the proliferation of a neointimal in a blood vessel through a MAPKs signal path. The application provides data for preparing lycorine hydrochloride into a medicine for inhibiting the proliferation of a neointimal in a blood vessel, and is expected to be applied to the prevention and treatment of complications after percutaneous coronary intervention, such as restenosis or in-stent thrombosis, and can become a potential medicine for intervening in restenosis.

The invention provides an auxiliary intelligent chip for nursing of a pci postoperative patient, and relates to the technical field of postoperative nursing assistance, and the intelligent chip comprises a data acquisition module which obtains historical rehabilitation information of a target user, and predicts and obtains a prediction state data sequence; the scheme generation module enumerates and generates a plurality of initial treatment schemes; the risk prediction module constructs a risk prediction channel based on machine learning, performs thrombus risk prediction and bleeding risk prediction in the stent, and outputs a plurality of risk prediction results; the risk evaluation module constructs a risk evaluation function, carries out comprehensive risk evaluation on a plurality of risk prediction results, and selects an initial treatment scheme with a minimum comprehensive risk coefficient as an optimal treatment scheme; and the decision pushing module takes the optimal treatment scheme as a nursing decision suggestion and sends the nursing decision suggestion to the target user for personalized auxiliary nursing. The technical problems that in the prior art, pci postoperative patient nursing scheme recommendation is unreasonable, and scheme adaptability is poor are solved.

The present invention is related to a synergistic bioactive composition comprising flavonoids and a mixture of long-chain alcohols for controlling platelet hyperactivity and associated thrombotic risk. The composition comprises the combination of anthocyanin(s) and policosanol. The combination of anthocyanin(s) and policosanol effectively regulates platelet hyperactivity. The composition of present invention offers a promising solution for neuro-cardiovascular and metabolic health by harnessing the synergistic effects of anthocyanin(s) and policosanol. Further, the invention provides synergistic action in controlling platelet hyperactivity associated with diseases like stroke, diabetes, atherosclerosis, dyslipidemia, stent thrombosis.