66 results about "Thrombotic risk" patented technology

The invention relates to a spontaneous cerebral hemorrhage postoperative intermuscular venous thrombosis risk prediction system based on a molecular mechanism and multi-modal data and a use method thereof, image space features are extracted through a multi-modal data level CNN to be complementary with time sequence features captured and detected by Transform, and support is provided for blood coagulation-endothelium-fibrinolysis three-channel activation degree calculation; a knowledge graph alignment module of a pathology and data level maps the cross-modal features to a unified semantic space, and corrects data conflicts with pathology time sequence constraints; and channel-space-time triple attention linkage at a space-time level is carried out, and a high-risk area is accurately marked. In a path driving layer, three-path activation degrees cooperatively adjust a dynamic time window, a single-path standard-exceeding triggering monitoring interval is shortened, and a double-path standard-exceeding amplitude is multiplied; and in a closed-loop feedback layer, system parameters are updated through confidence, pathological probability and conflict signal recursion, real-time calibration of a pathological mechanism and data is realized, and thrombus risk prevention and control efficiency is comprehensively improved.

The invention provides a multi-module collaborative clinical blood coagulation function intelligent evaluation and drug recommendation system, and relates to the technical field of medical information processing. Comprising a data acquisition and fusion module, a state recognition module, a drug intervention effect evaluation module, a decision recommendation module and a system visualization module. According to the system, continuous integration of clinical scattered data is realized by constructing a unified time sequence structure of multi-source detection indexes and medication records; generating a blood coagulation state vector containing the bleeding risk and the thrombus risk through a state recognition mechanism combining rule judgment and data calculation, outputting a confidence score and an index contribution degree, and forming a state track evolving along with time; performing causal evaluation on the difference of the state change before and after intervention to obtain a drug average treatment effect; and individualized drug suggestion or early warning information is generated based on the state track and the intervention effect. And dynamic evaluation and drug intervention measurement and calculation of the blood coagulation risk are realized.

The invention provides an artificial heart valve thrombus risk assessment method and device. The thrombus risk assessment method for the artificial heart valve comprises the following steps: acquiring a physiological scene after the artificial heart is implanted into the artificial valve through a resistance characteristic parameter and an elastic expansion characteristic parameter; starting a pulsating pump to output a pulsating flow medium to the artificial heart in a physiological scene; capturing the motion trail of the fluorescent particles through a high-speed camera and obtaining the original data of the blood flow velocity at the downstream of the artificial valve; acquiring a fluid mechanics simulation parameter group according to the blood flow velocity original data; and inputting a pre-trained valvular thrombus random forest classifier according to the fluid mechanics simulation parameter group, and outputting a thrombus risk probability graph in the physiological scene. According to the method, the fluid mechanics simulation parameter group is calculated based on the instantaneous velocity vector field captured by the PIV and the space-time distribution information, the two-dimensional / three-dimensional thrombus risk probability graph is generated through the random forest classifier, the high-risk point coordinates are marked, and the thrombus probability and the thrombus position are accurately predicted.

The invention relates to a blood rheological parameter online monitoring and thrombus risk assessment method, which comprises the following steps: introducing a blood sample into a microfluidic channel with a periodic geometric mutation structure, applying unsteady shear disturbance through a piezoelectric oscillation device, inducing blood to enter a non-equilibrium rheological state, and exciting a microcosmic coagulation tendency; the red blood cell aggregation behavior, the cell layer slippage phenomenon and the plasma shearing stability are recognized through the photo-thermal interference technology, and the rheological structure layer differentiation characteristics in blood are obtained; the blood subjected to shear disturbance is guided to a micro-channel high-pressure area provided with a flow-limiting threshold structure, and pressure mutation and microcoacervation nucleation generation behaviors induced by local stress disturbance are detected through a nanoscale piezoresistive sensor so as to identify sub-phase change response characteristics of the blood; and constructing a rheological instability index system on the basis of physical response signals obtained by shear disturbance, slippage and variable response, and when linkage abnormity of any two indexes is detected, judging that a high-risk event of thrombosis occurs and outputting a risk prompt signal.

The invention belongs to the technical field of air pressure treatment, and discloses a self-adaptive multi-point monitoring intelligent pulse anti-thrombus air pressure treatment system. Comprising the following steps: continuously collecting physiological parameters of a plurality of monitoring points of a patient, and constructing a parameter sequence; performing dynamic trend analysis on each parameter sequence in sequence, and extracting a corresponding physiological feature set; sequentially analyzing each group of physiological feature set, constructing a physiological feature sequence, comprehensively evaluating the risk score of each monitoring point, and dynamically evaluating the thrombus risk index of each monitoring point based on the risk score; fusing the thrombus risk index and the physiological feature sequence of each monitoring point, intelligently formulating an optimal treatment strategy, and carrying out differential parameter configuration on pulse air pressure treatment equipment; precise evaluation and personalized management of the physiological state of the patient in the air pressure treatment process are achieved, the treatment accuracy and effectiveness are improved, and the comfort and compliance of the patient are enhanced.

The invention provides a method and a system for evaluating thrombus risk before an internal arteriovenous fistula operation, and relates to the field of medical data processing, and the method comprises the following steps: based on the medical history information, treatment information and postoperative thrombus monitoring information of a plurality of internal arteriovenous fistula operation patients, evaluating the thrombus risk before the internal arteriovenous fistula operation; determining a plurality of thrombus risk related diseases, thrombus risk related operations and thrombus risk related drugs, and determining a plurality of internal arteriovenous fistula operation patient types; based on the medical history information and the treatment information of the patient to be subjected to the internal arteriovenous fistula operation, the type of the patient to be subjected to the internal arteriovenous fistula operation is determined, and preoperative detection information of the patient to be subjected to the internal arteriovenous fistula operation is obtained; and performing thrombus risk assessment before the internal arteriovenous fistula operation by combining the key preoperative detection factor corresponding to the type of the internal arteriovenous fistula operation patient and the influence weight corresponding to the key preoperative detection factor, thereby improving the efficiency and accuracy of thrombus risk assessment before the internal arteriovenous fistula operation.

The invention discloses a big data analysis-based abnormity identification method and system in a blood coagulation process, and the method comprises the steps: combining standard blood coagulation detection and thrombelastogram dynamic monitoring, achieving the spanning from a static index to function whole-course evaluation, combining the individualized features of a patient to screen historical similar cases, and precisely identifying a key blood coagulation index; according to the method, the accuracy and timeliness of blood coagulation state monitoring are remarkably improved, individualized early warning and intervention basis is provided for clinic, the risk of bleeding or thrombus is effectively prevented, and the clinical application prospect is wide. And intelligent and refined development of blood coagulation management is promoted.

The invention discloses a hemodynamic monitoring system and a control method for an intermittent occlusion balloon catheter. The monitoring system comprises a blood flow pressure measurement module, a cardiac displacement measurement module, a thrombus monitoring module and an infusion pump control module. The control method comprises the steps that a right atrium and vena cava pressure threshold value is set, the size of a balloon is controlled and adjusted through an infusion pump, the relation between blood flow pressure and the pressure threshold value is continuously monitored, and then the expansion size and time of the balloon are fed back and adjusted; based on an automatic cold solution suction-discharge module, the cardiac displacement change is indirectly measured; in the treatment process, parameter changes such as cardiac displacement, right atrium pressure and vena cava pressure of a patient are measured, and whether the patient recovers hemodynamics or not is monitored, and safe machine withdrawal conditions are met; and the thrombus risk condition near the balloon is analyzed through the thrombus monitoring module. The size and time of the balloon are adjusted through pressure feedback, and the infusion precision is improved; and machine withdrawal judgment conditions are set, so that the treatment effect of the patient is improved.

The invention discloses a multi-parameter thrombus risk detector, and relates to the technical field of medical instruments, the multi-parameter thrombus risk detector comprises a test unit, and the test unit comprises a first blood storage tube, a capillary tube, a second blood storage tube, a driving system and a detection system. The first blood storage tube is used for storing a whole blood sample; part of the inner wall of the capillary tube is coated with collagen, and part of the inner wall of the capillary tube is coated with serum albumin; the capillary tube is used for circulating whole blood and providing a space for forming thrombus, two ends of the capillary tube are respectively an inlet end for inputting the whole blood into the capillary tube and an outlet end for outputting the whole blood in the capillary tube, and the inlet end of the capillary tube is communicated with the first blood storage tube; the second blood storage tube is communicated with the outlet end of the capillary tube and is used for storing whole blood flowing out of the capillary tube; scales for indicating the volume of internal liquid are formed on the wall surface of the second blood storage tube; the driving system is used for driving total blood in the first blood storage tube to flow into the capillary tube and then flow into the second blood storage tube for storage; according to the invention, the individual thrombosis risk can be accurately evaluated.

The invention discloses an integrated valvular catheter and a preparation method thereof, relates to the technical field of medical instruments, and aims to solve the problems that in a traditional valvular catheter operation, suturing is tedious, tearing and thrombus risks exist, and adaptability is insufficient. The integrated valve-containing pipeline is composed of a valve leaflet and a pipeline body which are integrated through the sintering effect, sewing is not needed, and the reflux and thrombus risks caused by sewing gaps are effectively avoided; a metal memory alloy support is embedded in the wall of the pipeline, so that support can be provided for the valved pipeline to stabilize haemodynamics and prevent the pipeline from collapsing, endovascular intervention delivery can be achieved, and the device is adaptive to a surgical opening mode or an endovascular implantation mode and is used for replacing the valved pipeline at parts such as pulmonary artery and lower limb deep vein of a human body and recovering the function of the damaged valve.

This invention discloses an intelligent control method for a catheter pump based on electrical parameters. By collecting electrical parameters such as the current, voltage, and speed of the drive motor, and applying a neural network constructed using the Matlab toolbox or written code, the output flow rate is accurately estimated, eliminating the risks of infection and thrombosis associated with traditional invasive flow detection. The nonlinear mapping capability of the neural network effectively overcomes the shortcomings of traditional indirect measurement methods in complex operating conditions due to insufficient accuracy. The model developed based on the Matlab platform has good portability and can be converted into embedded code for real-time execution on a microcontroller, reducing system cost and power consumption. Finally, through closed-loop feedback control, automatic and precise adjustment of the catheter pump flow rate is achieved, completing the technical closed loop from non-invasive sensing to intelligent control, meeting the needs of precise clinical treatment.

The application discloses a method and system for identifying abnormalities in the coagulation process based on big data analysis, comprising: combining standard coagulation detection and thromboelastography dynamic monitoring to realize the leap from static indicators to functional whole-process evaluation, while combining patient individual characteristics to screen similar historical cases, and accurately identifying key coagulation indicators; introducing correlation analysis to dynamically screen key indicators, and using clustering analysis to establish an adaptive normal range, and finally evaluating abnormalities by quantifying the degree of deviation, the application significantly improves the accuracy and timeliness of coagulation state monitoring, provides individualized early warning and intervention basis for clinical practice, effectively prevents bleeding or thrombosis risk, and promotes the intelligent and refined development of coagulation management.

The present invention provides compositions and methods for inhibiting thrombosis in subjects at risk of thrombosis, such as those with a genetic, acquired, or environmental risk of thrombosis. [Solution] The present invention provides RNAi agents, such as double-stranded RNAi agents, that target kallikrein B, plasma (Fletcher factor) 1 (KLKB1) gene, factor XII (Hageman factor (F12) gene, or kininogen 1 (KNG1) gene, as well as methods for inhibiting the expression of the KLKB1 gene, F12 gene, and / or KNG1 gene using such RNAi agents, and methods for treating subjects with hereditary angioedema (HAE) and / or contact activation pathway-related disorders.

The invention relates to the technical field of medical data processing, in particular to a children thrombus risk prediction model and an active monitoring system. The model comprises a first network used for screening an initial data set collected in real time according to names of child medical indicators in a preset first data set, and setting a time sequence mark for data with a time sequence change characteristic in the screened data to obtain the first data set; extracting a second feature from the data provided with the time sequence mark based on the time change trend of the data, and adding the second feature into the first data set; the second network is used for inputting the first data set into a plurality of first models, and the first models comprise a plurality of different path relations learned through pre-training; probability values in the path relation are obtained through a first feature learned by a first model in a pre-training stage, and a risk probability is calculated based on the multiple probability values; by introducing dynamic real-time data, the prediction model better fits the clinical logic of children's thrombus attack, and the prediction accuracy is improved.

The invention relates to the field of medical health and intelligent optimization, and discloses a dialysis anticoagulation risk intelligent early warning method and system fused with multi-modal physiological signals, and the method comprises the steps: S1, synchronously collecting the multi-modal data of a patient in the dialysis process, and standardizing the multi-modal data into a unified time sequence matrix; s2, inputting the unified time sequence matrix into an anticoagulation risk prediction model, performing first-class feature extraction on continuous monitoring signals, performing second-class feature extraction on discrete detection signals, and extracting embedding features of patient individualization and treatment scene data; performing cross-modal fusion on the three types of extracted features to generate a fusion feature vector, and outputting a thrombus risk probability and a bleeding risk probability in a future preset time period; s3, when the risk probability exceeds the corresponding early warning threshold value, performing search optimization on the administration parameter of the current anticoagulant, and generating a dose adjustment instruction; and S4, executing the adjustment instruction, predicting the anti-coagulation risk again, and evaluating the regulation and control effect. Therefore, the safety and effectiveness of the hemodialysis process are remarkably improved.

The application discloses a sports nutrition food composition for blood vessel health and post-exercise recovery. Each 40g contains soybean protein isolate, whey protein, resistant dextrin, inulin, ginkgo biloba extract, hawthorn extract, grape seed extract, sea buckthorn peptide, natto powder (containing natto kinase), coenzyme Q10, natural vitamin E, vitamin C, bacillus subtilis DE111 and mineral probiotic premix. The application realizes blood vessel cleaning and post-exercise recovery through the synergy of multiple pathways such as direct thrombolytic effect of natto kinase, anti-platelet aggregation of ginkgo biloba / hawthorn / grape seed, protection of blood vessel endothelium by coenzyme Q10 / VE / VC, and regulation of intestinal tract by bacillus subtilis DE111. In-vitro thrombolysis experiment shows that the composition has clear fibrinolytic activity. All components meet the national standard of sports nutrition food, are safe and compliant, and are suitable for people with thrombosis risk and people who need blood vessel repair after high-intensity exercise.

The invention discloses a preparation method of a silk conical artificial blood vessel with anticoagulation / endothelialization promotion functions, which comprises the following steps: preparing an artificial blood vessel for intracavity isolation through silk and polyester yarns, and successfully constructing a phosphorylcholine / heparin bionic functional coating on the surface of the blood vessel by using dopamine hydrochloride and hexamethylenediamine. According to the method, phosphorylcholine / heparin is combined with surface coating modification, and a novel intracavitary isolated blood vessel with excellent biological functions and mechanical properties is constructed. The structure of the artificial blood vessel is more matched with the shape of the inner wall of the blood vessel, blood flow distribution and tissue regeneration are facilitated, the anticoagulant property and endothelialization ability of the artificial blood vessel are effectively improved through the phosphorylcholine / heparin coating, protein adsorption and platelet activation can be remarkably reduced, the blood coagulation cascade reaction can be blocked, endothelial cell adhesion and proliferation can be accelerated, and the risk of acute thrombus after operation can be reduced. The method provides a new technical path for design and functionalization of the conical artificial blood vessel in the intracavitary isolation operation, and has important clinical application prospects.

The invention discloses a left iliac total vein extravascular stent and an operation method, and belongs to the field of medical instruments. The stent comprises a middle section connecting sleeve frame, an inferior vena cava sleeve frame and a left iliac vein sleeve frame which are integrally formed, the included angle between the three is 135-145 degrees, an elastic silica gel limiting clamping belt is arranged and made of a silicon rubber material, and the crosslinking density and flexibility are regulated and controlled by adjusting the vinyl content. The surgical method comprises the following steps of: minimally invasive laparoscopic approach, implanting a stent after exposing a target blood vessel, and adjusting the position. Direct contact between the built-in stent and the intima is avoided, the intima hyperplasia and thrombus risks are reduced, fatigue resistance and creep resistance are achieved, the stent is attached to the anatomical structure, fixation is stable, minimally invasive recovery is fast, customizable adaptation can be achieved, and the clinical treatment effect and safety are improved.

This invention discloses a limb care device after cardiovascular interventional surgery, belonging to the field of medical auxiliary device technology. It includes a positioning unit, a compression unit, and a control unit. Through targeted structural design and collaborative control logic, it solves the contradiction between hemostasis and ischemia prevention in postoperative care, while improving nursing efficiency, stability, and safety. It uses the functional zoning of the central balloon in the puncture core area and the annular balloon in the surrounding auxiliary area, combined with the control logic that prioritizes the central balloon over the annular balloon, the annular balloon immediately stops circulation to maintain pressure when the pressure of the central balloon fluctuates. This ensures continuous hemostasis at the puncture site and avoids the risk of ischemia and thrombosis caused by long-term compression. The pressure threshold limitation, circulation reflux design, and emergency pause mechanism form multiple safety protections, reducing the risk of complications such as swelling and pain. It is also suitable for multiple puncture sites and patients of different body types, taking into account both medical and nursing efficiency and patient comfort.

The invention discloses a stent based on a full-drug-based structure function integrated composite coating and a preparation method and application thereof, and belongs to the technical field of medical instruments.The stent comprises a stent body, tannic acid coatings and EP-C9 polypeptide coatings are sequentially arranged on the outer surface of the stent body from inside to outside, the tannic acid coatings and the EP-C9 polypeptide coatings are alternately arranged, and the tannic acid coatings and the EP-C9 polypeptide coatings are sequentially arranged on the outer surface of the stent body from inside to outside. One tannic acid coating and one EP-C9 polypeptide coating are marked as one group, N groups are arranged in total, and N is greater than or equal to 1. The stent has excellent antithrombotic and anti-inflammatory functions and has no carrier residue side effect, components of the coating are functional molecules and structural molecules and are completely absorbed by a body after playing pharmacological action, and the problem that a traditional stent has inflammation and thrombus risks is fundamentally solved.

The invention provides a wound repair material and a preparation method thereof, and relates to the field of biomedical materials. The preparation method of the wound repair material comprises the following steps: mixing alpha-cyanoacrylate and acetone to obtain an adhesion matrix solution; mixing polyvinyl butyral, quaternized cellulose, dexamethasone and an organic solvent to obtain a functional additive solution; and performing double-needle array electrostatic spinning on the adhesion matrix solution and the functional additive solution to obtain the wound repair material. The wound repair material prepared by the invention has the functions of relatively high adhesion, antibacterial ability, anti-inflammatory ability, biocompatibility and the like, can avoid side effects such as thrombus risk and the like, and can be safely and efficiently adapted to healing environments of different wounds.

The invention discloses a chest catheter expansion stent and an expansion stent system, and belongs to the technical field of medical instruments, the chest catheter expansion stent comprises a cylindrical grid stent section and a flower-shaped stent section, the cylindrical grid stent section is used for being implanted into a chest catheter arch, and the flower-shaped stent section is used for being indwelled in veins; the flower-shaped stent section comprises hollowed-out petals arranged in the circumferential direction, and the hollowed-out petals are bent towards the far end of the cylindrical grid stent section. The dilation stent system comprises a conveying device and a chest catheter dilation stent. The near end of the thoracic duct expansion stent is in a flower shape, hollow petals are bent outwards, the thoracic duct-vein angle tissue can be attached more tightly, the contact area is increased, radial stress is dispersed, progressive supporting force is provided, stent displacement is avoided, a good anchoring effect is achieved, and the stability of the thoracic duct expansion stent is improved. The continuous injury to the intravenous intima is reduced, the thrombus risk is reduced, the elastic retraction of the chest catheter wall is effectively resisted, and the restenosis is prevented from the source of mechanical design.

The invention provides a low-trauma sheath-free in-aorta balloon catheter, and belongs to the technical field of aorta balloon counterpulsation. Comprising an outer catheter, a main balloon is arranged at the far end of the outer catheter and used for blocking aorta blood flow, and an auxiliary balloon located at the near end of the main balloon is arranged on a catheter body of the outer catheter and used for anchoring the position of the outer catheter when the auxiliary balloon is inflated and expanded. The near end of the outer catheter is provided with a connecting part which is arranged outside the human body and used for sucking, deflating and inflating the main balloon and the auxiliary balloon and allowing a guide wire to penetrate through, an inner tube is arranged in the outer catheter, and an anticoagulant perfusion part is arranged on the outer catheter. A sheathing canal is omitted, direct percutaneous puncture implantation is achieved, blood vessel injury is reduced, through a double-balloon structure, the main balloon is located at the far end of the catheter and used for aorta blood flow blocking, and the auxiliary balloon is located at the near end of the main balloon and can be filled to form an anchoring structure to prevent catheter displacement; and the anticoagulant is conveyed into the aorta from the agent outlet head through the anticoagulant infusion tube, so that the vascular injury and thrombus risk can be effectively reduced.

The application provides a track type three-leaflet mechanical valve. The track type three-leaflet mechanical valve comprises a ring-shaped support and valve leaves, the ring-shaped support is a hollow columnar structure, the valve leaves comprise trailing edges and leading edges connected to the ring-shaped support; the valve leaves are three, the three valve leaves are sequentially and spacedly arranged along the circumference on the inner wall of the ring-shaped support, the inner wall of the ring-shaped support is provided with movement tracks matched with the valve leaves, the movement tracks accommodate and receive the leading edges of the valve leaves; the inner wall of the ring-shaped support is provided with a partition body between adjacent valve leaves, the partition body separates the valve leaves and supports the end portions of the valve leaves. The application optimizes the structure, improves the fluid dynamics performance, reduces the interference to blood flow, optimizes the blood flow performance, enhances self-cleaning, and reduces the thrombosis risk.

Methods of reducing the risk of venous thromboembolism (VTE) in a subject undergoing anticoagulant treatment by selectively depleting Factor V Leiden (FVL) in a subject that is heterozygous for FVL, or replacing FVL in the genome of a subject that is homozygous for FVL with a functional Factor V gene, and methods of identifying a subject undergoing anticoagulant treatment who is at risk of developing VTE are disclosed herein.

The invention discloses an artificial blood vessel and a preparation method and application thereof, and relates to the technical field of artificial blood vessels, the artificial blood vessel comprises an artificial blood vessel stent material and a coating material at least partially coating the surface of the artificial blood vessel stent, and the coating material comprises a platelet coating, a GPIIb / IIIa receptor on the surface of a platelet membrane in the platelet coating is in a closed state. The platelet coating on the surface of the artificial blood vessel stent can promote recruitment, migration and proliferation of endothelial cells, so that the endothelialization process of the artificial blood vessel is accelerated; the GPIIb / IIIa receptor on the surface of the platelet membrane is in a closed state, so that the thrombus risk caused by platelets in the subsequent endothelialization process is avoided, and the blood coagulation function and the endothelialization function of the platelet coating are decoupled. The artificial blood vessel does not need additional chemical modification, the coating is biodegradable, and inflammation and foreign matter rejection phenomena caused by a traditional coating are avoided.

The utility model provides an anti-skidding back cushion for adjusting an intraoperative body position, which belongs to the technical field of the intraoperative body position back cushion and comprises a support component with an inclined plane design, a magic tape hook claw arranged at the bottom of the support component and a polyurethane coating coated on the surface of the support component, the supporting assembly comprises a supporting part, shoulder supports located on the two sides of the top of the supporting part, an arc-shaped groove located between the two shoulder supports and a supporting inclined face located at the front end of the supporting part. By means of the supporting assembly with the inclined face design, the situation that a patient slides down in the operation can be prevented, the head posture adjusting function is achieved, the head is kept in a slightly-raised posture all the time, and the thrombus risk in the operation can be reduced; the polyurethane coating can increase friction force between a patient and the surface of the back cushion, the shoulder supports and the arc-shaped grooves provide stable shoulder and head support, blood circulation is optimized, and therefore safe and comfortable body position support is provided for the patient in a complex operation environment.

A valve clamping device relates to the technical field of medical instruments and comprises a base, a first clamping piece, a second clamping piece and a first covering film. The base is provided with a first end face, a second end face, a first side face and a second side face, the first end face is opposite to the second end face, and the first side face and the second side face are oppositely arranged on the two sides of the first end face and the second end face. The first clamping piece is movably arranged on the first side face of the base, and the second clamping piece is movably arranged on the second side face of the base. Wherein a first covering film is attached to the first end face and the second end face, by arranging the first covering film, the base can have a soft and continuous surface, the valve clamping device is more friendly to internal tissues of the human body in the process of being implanted into the human body, the thrombus risk is reduced, and the operation safety is improved.

This invention discloses a home-based intelligent monitoring and rehabilitation training system, method, terminal, and medium for arteriovenous fistulas (AVFs), relating to the field of smart medical technology. The system includes: home-based devices, a cloud server, and a software interactive management platform. The home-based devices include an AVF monitoring wristband and an intelligent arm exerciser. The AVF monitoring wristband collects AVF blood flow acoustic signature data and provides early warnings to the patient. The intelligent arm exerciser collects motion parameters and provides rehabilitation training and movement guidance functions for the patient. The cloud server processes the collected AVF blood flow acoustic signature data and motion parameters, performs thrombosis risk analysis, and generates a rehabilitation training plan. The software interactive management platform allows real-time viewing of the patient's AVF status, rehabilitation training plan, and exercise records. This invention fills the gap in integrated home-based AVF monitoring, early warning, rehabilitation training, and feedback, providing an intelligent solution for reducing AVF failure rate and extending AVF lifespan.

The application relates to the technical field of nerve electrophysiological monitoring, and discloses an intravascular brain electrode. The electrode comprises a flexible net-shaped support adopting an M-shaped weaving structure, a micro recording point independently arranged at a node of the support, and a flexible wire system. The support has a zero axial shortening characteristic and generates a mild radial supporting force after expansion; and the recording point has a directional collection structure for blocking blood shunt. The application realizes mechanical decoupling through M-shaped structure and node fixation, eliminates motion artifacts, improves the signal-to-noise ratio by using directional collection, and reduces the risk of thrombosis by cooperating with a high open hole rate, so that the technical problems of "uncertain measurement", "incomplete measurement" and "insecurity" are solved in one station.