31results about How to "Improve deliverability" patented technology

The present invention is directed to an intravascular treatment for intracranial aneurysms. The invention consists of a patch stent and, also, a patch stent delivery system allowing one to rotate the stent to align the patch with the neck of the aneurysm. A self-expanding nitinol framework holds the patch in place, a radiopaque agent allows the patch location to be visualized and a pusher tube that is mechanically locked into the unexpanded stent is used to push the stent out of the catheter with rotational and longitudinal control necessary to align the patch with the aneurysm. A self-expanding framework is used to support a patch at the neck of the aneurysm. The patch is designed to reduce the blood circulation in the aneurysm and the stagnant blood will clot or thrombus. The thrombus will stop any current blood leakage into the brain and will dramatically reduce the possibility of future leaks or potentially deadly ruptures. Over time the thrombus will be absorbed and the volume of the aneurysm will shrink reducing pressure on surrounding tissue.

A modification to allow delivery of a two port medical flow restrictor over a guidewire, and a means to mechanically collapse the new device. A thin walled, foil-like shell, is compacted for delivery. The invention includes the device, delivery assemblies, and methods of placing, and using, the device. A device with an aneurysm lobe and an artery lobe self-aligns its waist at the neck of an aneurysm as the device shell is pressure expanded. Mechanical force collapses both the aneurysm lobe and the artery lobe, captivating the neck of the aneurysm and securing the device. The device works for aneurysms at bifurcations and aneurysms near side-branch arteries. The device, unlike endovascular coiling, excludes the weak neck of the aneurysm from circulation, while leaving the aneurysm relatively empty. Unlike stent-based exclusion, the device does not block perforator arteries. This exclusion device can also limit flow through body lumens or orifices.

A catheter tip that provides longitudinal flexibility, pushability and radial rigidity thereby improving deliverability is provided. The catheter tip includes a spring-like element to provide longitudinal flexibility and pushability to the catheter tip. The spring-like element may also provide radial support to the distal edge of the catheter tip. Alternatively, a radially rigid distal end may also be included distal of the spring-like element. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

Disclosed herein are various open / closed stent designs and methods for creating the same that can be individually adopted depending on particular treatment objectives. Specifically, the stents of the present invention are manufactured to include different open / closed configurations along their length by varying the number of crossovers, connectors or weld points between sections of the stent. Open portions contain less crossovers, connectors or weld points and are more flexible than closed portions which contain more crossovers, connectors or weld points.

A modification to allow delivery of a two port medical flow restrictor over a guidewire, and a means to mechanically collapse the new device. A thin walled, foil-like shell, is compacted for delivery. The invention includes the device, delivery assemblies, and methods of placing, and using, the device. A device with an aneurysm lobe and an artery lobe self-aligns its waist at the neck of an aneurysm as the device shell is pressure expanded. Mechanical force collapses both the aneurysm lobe and the artery lobe, captivating the neck of the aneurysm and securing the device. The device works for aneurysms at bifurcations and aneurysms near side-branch arteries. The device, unlike endovascular coiling, excludes the weak neck of the aneurysm from circulation, while leaving the aneurysm relatively empty. Unlike stent-based exclusion, the device does not block perforator arteries. This exclusion device can also limit flow through body lumens or orifices.

A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon.

A vascular filter device (1) has a perfusion balloon (3) with a through-hole for blood flow. There is a distal filter (4) for trapping emboli, and the filter (4) is configured to filter an annular cross-sectional area extending from a vessel wall, while leaving an un-filtered central passageway. The filter (4) may be substantially frusto-conical in shape when deployed, and have a proximal tubular part (41) which is attached to the perfusion balloon or a support for the perfusion balloon. The filter has a retainer (5) to retain an end of the filter in an in-use position abutting a vessel wall. The retainer may comprise wires (5) or an inflated ring (8). The device may have an internal support (2, 12, 22, 96, 112) for the perfusion balloon (3, 11, 21, 95, 111). The balloon inflates and expands the inner arterial wall, and the filter captures emboli released during the procedure while leaving a channel that allows blood to flow to tissues distal to the blockage, maintaining antegrade flow. This may prevent the onset of an ischemic stroke or other perioperative neurological events.

Device and method significantly that improves the safety and procedural success of the existing art by being able to be less traumatic to vascular tissue, improving atrial contact with the ablation surface, improving positioning and geometrical precision of the ablation pattern, improving steerability and deliverability of the ablation device and by improving localization and geometric precision of the ablation device. The risk of pulmonary vein fibrosis / stenosis will also be substantially lowered. Finally, expansion of the eligible atrial fibrillation population will inherently increase due to the improved components and methods of the present invention.

Medical devices such as catheter-based technologies for therapeutic interventions in the coronary arterial circulation and other vascular beds are presented. Apparatus, systems and methods for improving the performance and / or operability of catheter navigation through a vascular pathway are presented. Deliverability of vascular therapeutic devices is improved through mechanical catheter control systems.

A medical or dental treatment device for dispensing a medium having a base part with a power supply unit and an electrical or electronic control device and at least one delivery part that can be connected detachably to the base part via a coupling device and which has a sound source, such as an ultrasound source, and a delivery device for dispensing the medium from the delivery part. In addition, at least one active part, which can be connected detachably to the base part via the coupling device, may also be provided.

The present invention aims to provide a cationic lipid that can be used as a nucleic acid delivery carrier, a lipid membrane structure using a cationic lipid, a nucleic acid-introducing agent using a cationic lipid, and a method of achieving nucleic acid introduction by using a nucleic acid-introducing agent containing a cationic lipid. A lipid membrane structure containing a cationic lipid represented by the formula (1)wherein each symbol is as defined in the DESCRIPTION, is superior in the stability in blood and tumor accumulation property. A nucleic acid-introducing agent using the cationic lipid can achieve high nucleic acid delivery efficiency of nucleic acid to be delivered into the cytoplasm.

An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The apparatus and method, which are appropriate for cardiovascular and peripheral vessels, use a pulling member and a spring member, for example a compression spring, to oscillate a drilling component. The drilling component at the distal end of the catheter tip has combined longitudinal stiffness for penetrating a total or partial occlusion and high axial (lateral) flexibility to improve deliverability and crossability of a catheter through a partially occluded vessel or a tortuous vessel, and may taper distally. The system of the invention includes the apparatus and a control unit to permit adjustment of the frequency or amplitude of oscillation of the drilling component. Also provided is a method for oscillating a drilling component using a pulling member and a spring member and a method of traversing an occlusion.

A catheter tip having a spring element that imparts longitudinal flexibility, pushability and radial rigidity to the catheter tip, thereby improving deliverability, is provided. The spring element also provides radial support to the distal edge of the catheter tip. The spring element may taper distally, but may have a substantially constant inner luminal diameter. The spring element may be partially covered or embedded, leaving its distal end exposed. The spring element may also include spaced coils in a proximal region. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

A medical or dental treatment device for use in an oral or dental procedure, comprises a base part with a power supply unit and an electrical or electronic control device and a set of different parts for use with the base part. The set of different parts comprises at least one delivery part for a first treatment phase and comprising a sound or ultrasound source, a movable piston and a piston operating element operable to deliver a substance from the delivery part to a treatment site, and at least one active part for use in a second treatment phase to act on the treatment site. The active part comprises a sound source, an ultrasound source and / or an electromagnetic radiation source. The delivery part and the active part are selectively connectible to the base part for use in consecutive treatment phases (the first can precede or follow the second).

The invention relates to the use of calcium complex and calcium sulfate complex lubricating grease compositions as lubricants for wire ropes. The invention further relates to a method for producing the wire ropes and to wire ropes provided with the lubricating grease composition.

Advancements in solid tumor (e.g., renal cell carcinoma) treatments and imaging are described. The advancements are based on nanoformulations that: (i) overcome deliverability issues associated with anti-cancer compounds; (ii) have increased targeted delivery to tumors, and hypoxic cores of tumors due to the presence of targeting ligands; (iii) have increased delivery to the hypoxic cores of tumors due to engineered shapes; (iv) provide synergistic treatment combinations; and / or (v) overcome cancer cell resistance to therapeutic treatments.

An apparatus having a processing unit for using information stored in a storage unit to calculate a producible number of each item is disclosed. The processing unit sets up a steady mode or a non-steady mode based on input information or the information stored in the storage. The processor unit operates, in the steady mode, to calculate a producible number by using a supply path stored in a supply path storage unit. In the nonsteady mode, the processor sets up a time taken for an item to be moved between hubs not being stored in the supply path storage unit, and repeatedly computes, from end-piece parts of an item configuration up to the product, a quantity of a parent item having the item as its component when this item is transferred between the hubs by use of an inventory or work-in-process quantity, thereby calculating the product producible number.

A stent in a radially compressed configuration includes a plurality of first outer crowns and a plurality of second outer crowns, each of the first outer crowns and the second outer crowns connected by a strut of a plurality of struts. The plurality of first outer crowns and the plurality of second outer crowns are disposed at a crown angle in the range of about 15 degrees to about 35 degrees, the crown angle being defined by a line extending through a midpoint of a crown of the plurality of first outer crowns or the plurality of second outer crowns through a center of radius of the crown with respect to a line that is parallel to a central longitudinal axis of the stent.

The present invention relates to devices, systems and methods to maintain self-expanding stents in a compressed form during delivery to and positioning at a treatment site. The devices, systems and methods of the present invention can provide for more accurate stent positioning and can improve the deliverability of self-expanding stents. Designs of the devices, systems and methods of the present invention include slotted designs, tethered designs and encapsulating flexible sheath designs.

The invention discloses a k8s-oriented user mode virtual device driving framework, which virtualizes IO (Input / Output) devices into a plurality of virtual devices sharing hardware resources by adopting an SRIOV (Single Radio Input / Output Virtualization) technology, maps IO addresses and interrupts of the virtual devices into a pad container of a pad, and runs a driving program of the virtual devices in the pad container. Other application containers in the pod access the drive program in the pause container in a memory sharing mode. The framework provides contents such as virtual equipment management, application program and driving program communication interfaces, a user only needs to compile a driving code of specific equipment under the framework, and the complexity of compiling an equipment driving program is reduced. According to the framework, a virtualization and transparent transmission mode is adopted, most functions of a device driver are transplanted into a pause containerto be achieved, the framework can be delivered together with an application program, and the isolation and deliverability of the driver and the reliability of a system are improved while the device efficiency is guaranteed.

A catheter tip that provides longitudinal flexibility, pushability and radial rigidity thereby improving deliverability is provided. The catheter tip includes a spring-like element to provide longitudinal flexibility and pushability to the catheter tip. The spring-like element may also provide radial support to the distal edge of the catheter tip. Alternatively, a radially rigid distal end may also be included distal of the spring-like element. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

The present disclosure provides a message push method and device, wherein the method includes: when it is determined that the cached information corresponding to the target application on the client is cleared, and sending a notification bar message corresponding to the target application to the client terminal, re-register the message push function for the preset platform on the client; push the notification bar message to the client based on the re-registered message push function; wherein, the preset platform is the client A platform for running the target application on the background, the target application is an application whose installation and download process does not require user confirmation, and the installation and download process runs in the background of the client. This disclosure realizes the purpose that even if the cache information corresponding to the target application on the client is cleared, the server can still push the notification bar message to the client, improves the delivery ability of the notification bar message corresponding to the target application, and improves the user experience. experience.

The invention provides a data pushing method and device, electronic equipment and a storage medium. According to the data pushing method, the user type of the target user is determined according to the clothes washing data of the target user and the preset user type mapping relation, and the clothes washing data is used for recording the clothes washing habit of the target user; and then determining a pushing time period corresponding to the target user according to the user type so as to push the clothes washing report to the target user in the pushing time period. Therefore, the pushing time period is determined based on the clothes washing data, and the clothes washing report is pushed to the target user in the pushing time period, so that the target user can receive and check the clothes washing report in the appropriate time. The delivery rate and the delivery effect of the clothes washing report are effectively improved, so that the intelligent washing machine is humanized, and the use experience of a user is improved.

The invention provides a message pushing method and device. The method comprises the following steps: when determining that cached information, which corresponds to a target application, on a client side is cleared away and a notification bar message which corresponds to the target application is transmitted to the client side, re-registering a message pushing function for a preset platform on theclient side; and pushing the notification bar message to the client side on the basis of the re-registered message pushing function. The preset platform is a platform which is used for running the target application on the background of the client side, and the target application does not need to be confirmed by a user in installing and downloading processes, and runs on the background of the client side in the installing and downloading process. Even if the cached information, which corresponds to the target application, on the client side is cleared away, a server side still can push the notification bar message for the client side, the delivery ability of the notification bar message corresponding to the target application is improved, and user experience is improved.

The invention discloses a real-time stable notification sending method, which comprises the following steps that: a background server adds a marking field according to whether push information to be sent to a mobile terminal is important or not, and pushes the marking field to the mobile terminal; the mobile terminal analyzes the marking field pushed by the background server, judges whether the pushed message is important or not, and pushes the message through aurora sdk if the pushed message is important; and when the mobile terminal does not receive the push message, the background server pushes the push message to the user mobile terminal in a short message sending mode. According to the invention, the timeliness and the delivery rate of the pushed message can be greatly improved, and the current situation that the pushed message cannot be delivered in time due to various special reasons after the aurora pushing mode is integrated is solved.

The invention relates to the use of calcium complex and calcium sulfate complex lubricating grease compositions as lubricants for wire ropes. The invention further relates to a method for producing the wire ropes and to wire ropes provided with the lubricating grease composition.