The invention discloses a manual-operated clothes washing device which comprises a washboard. The bottom of the washboard is in movable connection with the bottom of a squeezer, a washboard handle is arranged on the top of the washboard, and a squeezer handle is arranged on the top of the squeezer. The washboard handle and the squeezer handle are fixed or movable handles. The squeezing face of the squeezer is provided with beads or convex points or concave grooves, the washboard, a base and a container are connected, the washboard and the squeezer are in opening-closing movement through manual operation, and beads of the washboard and the beads of the squeezer are in a meshing state when being combined together. The clothes washing washboard can be used for washing clothes and also can squeeze water of the clothes when sewage is poured, environmental protection, energy saving and low carbon are achieved, the process of washing the clothes in the clothes washing container, squeezing the water of the clothes and pouring the sewage can be achieved by a single hand, and the demand for washing the clothes of special people is met.