Compound calcium preparation for astronaut

A technology for astronauts and calcium preparations, which is applied in the direction of medical preparations containing active ingredients, drug combinations, active ingredients of aluminum/calcium/magnesium, etc., and can solve problems such as impact, easy calcium deposition, and difficult fixation of calcium

Active Publication Date: 2008-09-17
BEIJING DAWN AEROSPACE BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the loss of bone calcium in different groups of people due to various reasons, which seriously affects health, coupled with changes in people's diet structure and living habits, it is difficult to supplement enough calcium and collagen protein from food, so calcium supplementation through various channels is becoming more and more important. The more people pay attention, there are many kinds of calcium preparations on the market. The general single calcium supplement has the disadvantages of low absorption of calcium in the small intestine and prone to calcium deposition.
Although the compound calcium supplement overcomes the above shortcomings to a certain extent, when the human body lacks collagen, it is not easy to fix calcium. Therefore, the situation of calcium loss cannot be improved, which in turn affects bone density and causes bone loss. Occurrence of loose matter

Method used

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  • Compound calcium preparation for astronaut
  • Compound calcium preparation for astronaut

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Experimental program
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Effect test

Embodiment 1

[0011] Calcium carbonate 40%, collagen peptide with an average molecular weight of 3Kda 33%, stachyose 15%, VD 3 0.0002%, soybean isoflavones or kudzu isoflavones 1.5%, pregelatinized starch 10%, magnesium stearate 0.5%.

[0012] In the above formula, calcium carbonate, stachyose, collagen peptide, VD 3 , Soybean isoflavones or kudzu root isoflavones are fully mixed. During the mixing process, 60% edible ethanol is sprayed into granules in a fine mist form, passed through a 20-mesh sieve, and dried at 80°C, and then pregelatinized starch, Magnesium stearate is mixed thoroughly, pressed into a tablet weighing 1 gram, three tablets a day.

[0013] The calcium preparation is suitable for calcium supplementation for female astronauts and middle-aged and elderly women.

[0014] Carry out the following animal experiments with this calcium preparation

[0015] 1 Animal grouping and feeding

[0016] Thirty-two female SD rats of SPF (specific pathogenic bacteria free) grade, weigh...

Embodiment 2

[0031] Calcium Carbonate 40%, Collagen Peptide 30%, Stachyose 17%, VD 3 0.0002%, pregelatinized starch 12.5%, magnesium stearate 0.5%.

[0032] The production process is the same as above.

[0033] The calcium preparation is suitable for calcium supplementation of calcium-deficient people except middle-aged and elderly women.

[0034] Carry out the following animal experiments with this calcium preparation

[0035] 1 Animal grouping and feeding

[0036] 40 male SD rats of SPF (specific pathogenic bacteria free) grade, weighing (160-180) g, were fed adaptively for 5 days, and randomly divided into 5 groups according to body weight, with 8 rats in each group:

[0037] Group A: normal control group, fed SPF grade common feed, calcium content was 1.1%;

[0038] Group B: normal low-calcium feed control group fed SPF grade low-calcium feed with a calcium content of 0.3%;

[0039] Group C: suspended control group, fed SPF grade low-calcium feed;

[0040] Group D: Suspension + ...

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Abstract

A composite Ca-supplementing food for the astronaut is prepared from calcium carbonate, collagen peptide, stachyose and VD3. Its advantage is efficient absorption by intestine and stomach.

Description

technical field [0001] The invention relates to a health care product, in particular to the formulation and production process of a high-efficiency compound calcium preparation aimed at combating bone calcium loss for astronauts working in a weightless space environment. Background technique [0002] When astronauts live in space for a long time, the weightless environment will accelerate the loss of bone calcium, seriously affecting the astronauts' health and work efficiency. Human bone tissue is composed of 1 / 3 organic matter and 2 / 3 inorganic matter. The inorganic matter of bone is mainly bone salt, 95% of which is solid calcium. The organic matter of bone includes collagen and non-collagen substances, and collagen accounts for more than 90%. Its network structure is very important for maintaining the integrity of bone structure and bone biomechanical properties. Due to the loss of bone calcium in different groups of people due to various reasons, which seriously affects...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/39A61K33/10A61K31/352A61K31/702A61P3/02
Inventor 陈斌
Owner BEIJING DAWN AEROSPACE BIO TECH
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