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Pharmaceutical composition used for chronic atrophic gastritis and preparation method thereof

A technology for atrophic gastritis and a composition is applied in the field of pharmaceutical compositions for chronic atrophic gastritis and the field of preparation thereof, and achieves the effects of simple preparation process, improved pepsin activity, and good improvement of pathological examination results.

Inactive Publication Date: 2009-09-02
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no report on the use of Qing Pinellia, Dendrobium, Radix Paeoniae Alba, and Radix Glycyrrhizae to prepare prescriptions for the treatment of chronic atrophic gastritis

Method used

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  • Pharmaceutical composition used for chronic atrophic gastritis and preparation method thereof
  • Pharmaceutical composition used for chronic atrophic gastritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] Embodiment 1: the preparation of pharmaceutical composition tablet of the present invention

[0099] Qing Pinellia 12g Dendrobium 15g White Peony 15g Roasted Licorice 10g

[0100] Weigh Pinellia chinensis, Dendrobium, Radix Paeoniae Alba, and Radix Glycyrrhizae, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2.5 hours, add 8 times the amount of water for the second time, decoct for 2 hours, combine the extracts, Filtrate, concentrate the filtrate to a relative density of 1.13-1.15, add ethanol until the alcohol content is 75%, stir evenly, refrigerate and let stand for alcohol precipitation for 24 hours, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate to Thick paste, dried, crushed, added binder, disintegrant and lubricant to make granules, dried, compressed into tablets.

Embodiment 2

[0101] Embodiment 2: the preparation of pharmaceutical composition capsule of the present invention

[0102] Qing Pinellia 10g Dendrobium 12g White Peony 12g Roasted Licorice 8g

[0103] Weigh Pinellia chinensis, Dendrobium, Radix Paeoniae Alba, and Radix Glycyrrhizae, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2.5 hours, add 8 times the amount of water for the second time, decoct for 2 hours, combine the extracts, Filtrate, concentrate the filtrate to a relative density of 1.13-1.15, add ethanol until the alcohol content is 75%, stir evenly, refrigerate and let stand for alcohol precipitation for 24 hours, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate to Thick paste, dried, crushed, added with binder to make granules, packed into hard capsules.

Embodiment 3

[0104] Embodiment 3: the preparation of pharmaceutical composition granule of the present invention

[0105] Qing Pinellia 15g Dendrobium 18g White Peony 18g Roasted Licorice 12g

[0106] Weigh Pinellia chinensis, Dendrobium, Radix Paeoniae Alba, and Radix Glycyrrhizae, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2.5 hours, add 8 times the amount of water for the second time, decoct for 2 hours, combine the extracts, Filtrate, concentrate the filtrate to a relative density of 1.13-1.15, add ethanol until the alcohol content is 75%, stir evenly, refrigerate and let stand for alcohol precipitation for 24 hours, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate to The thick paste is dried, crushed, and powdered sugar and binders are added to make granules.

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Abstract

The invention belongs to the technical field of medicine and discloses a pharmaceutical composition for chronic atrophic gastritis and a preparation method thereof. The crude drug used to prepare the medicinal components contained in the medicinal composition is mainly composed of Qing Pinellia, Dendrobium officinalis, Radix Paeoniae Alba and Radix Glycyrrhiza in certain weight proportions. It can be made into any clinically or pharmaceutically acceptable dosage form, preferably an oral preparation. The medicinal composition has the effects of harmonizing the stomach, nourishing the stomach, promoting body fluid, eliminating mass, dissipating stagnation, and relieving pain, and is used for chronic atrophic gastritis, and the effect is remarkable.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for chronic atrophic gastritis and a preparation method thereof. 2. Background technology [0002] Chronic atrophic gastritis is a common clinical disease characterized by the atrophy of the intrinsic glands of the gastric mucosa. . Finding effective and reliable medicines has always been a topic that the medical circles at home and abroad have been working hard to explore. Analyzing chronic atrophic gastritis from the perspective of traditional Chinese medicine is equivalent to "stomach fullness", "constipation", "gastric pain" in traditional Chinese medicine, etc. The pathological changes of chronic atrophic gastritis are based on positive and negative, including qi deficiency, yang deficiency and yin deficiency. Deficiency of three basic lesions. The three basic lesions are often intertwined with each other, manifested as qi-yang...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P1/04
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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