Preparation and application of 'dingguiyou' soft capsule

A technology of cinnamon oil and soft capsules, which can be used in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve problems such as outdated dosage forms, large doses, and low volatile oil content

Inactive Publication Date: 2008-07-02
牛锐
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The active ingredient of clove and cinnamon for treating stomach pain is volatile oil. The traditional usage is to add it to decoction or powder for application, but the content of volatile oil retained in decoction is low, and although powder can retain all the volatile oil, the

Method used

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Embodiment Construction

[0006] Prescription: Mix 50% cloves and 50% cinnamon to extract volatile oil to prepare cinnamon oil. 36ml of cinnamon oil, 364ml of soybean oil, 150g of gelatin, 60g of glycerin, 150g of deionized water, 10g of simple syrup, 0.15g of methyl p-hydroxybenzoate, and 0.075g of ethyl p-hydroxybenzoate are made into 1000 soft capsules .

[0007] Preparation method: Mix cinnamon oil and soybean oil and set aside. Take gelatin, glycerin, simple syrup and deionized water, mix well, heat to 60-70°C, keep warm for 0.5 hours, add methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, stir, vacuumize, keep warm at 70°C for 20 minutes , made of capsule material. The mixture of cinnamon oil and soybean oil is taken, and the capsule material is pressed into soft capsules.

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Abstract

The invention relates to a prescription which is mainly composed of clove and cinnamon, the indication of the prescription is irritable bowel syndrome, and the effective part of clove and cinnamon is volatile oil which is determined by screening of pharmacodynamics. The soft capsules which are prepared by the volatile oil have elegant appearance, convenient administration and stable quality; proved by pharmacodynamic tests, the soft capsules can meet the requirements of the clinical medication of irritable bowel syndrome.

Description

technical field [0001] pharmaceutical technology Background technique [0002] Clove and cinnamon are traditional Chinese medicinal materials, and are used in combination or alone to treat various stomach diseases with stomach pain as the main symptom. Soft capsules are a common dosage form, mostly used for fat-soluble drugs. [0003] The active ingredient of clove and cinnamon for treating stomach pain is volatile oil. The traditional usage is to add it to decoction or powder for application, but the content of volatile oil retained in decoction is low, and although powder can retain all the volatile oil, the dosage form is backward and inconvenient to take. The problem to be solved by the present invention is to extract the volatile oil of the active ingredient in it through a proper process and make it into an efficient and convenient dosage form for the treatment of irritable bowel syndrome. Contents of the invention [0004] A prescription for irritable bowel syndro...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K9/48A61P1/00A61P1/12
Inventor 牛锐
Owner 牛锐
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