Method and device for pressure dividing monitoring and estimating arterial blood CO2 by using respiratory gas CO2

Abstract

The invention discloses a method and a device using the expired gas partial pressure of CO2 to monitor and estimate the CO2 partial pressure of arterial blood, belonging to the clinical respiratory monitoring technology field. The technical points includes using a CO2 analyzing and monitoring instrument for the real-time acquisition on the expiratory flow, the time and CO2 partial pressure PaCO2 to be input into a computer; processing input data; when the instant flow is 22.25 plus or minus 0.08 percent or the instant slope of the flow speed / time curve is 0.13 plus or minus 0.19, (a) and the difference of the corresponding CO2 partial pressures is within about 5 percent, the average value of the corresponding CO2 partial pressure is basically the same with the arterial blood CO2 partial pressure; (b) the corresponding CO2 partial pressure difference is over about 5 percent, the mathematical model fitting is implemented on the CO2 partial pressure / time curve to estimate the corresponding arterial blood CO2 partial pressure. The invention can be applied to clinical wound-free monitoring COPD patients, especially the PaCO2 of severe COPD patients.

Description

technical field The present invention relates to a kind of clinical respiratory monitoring technology, more specifically, it relates to a kind of using exhaled gas CO 2 Partial pressure monitoring to estimate arterial blood CO 2 pressure dividing device. Background technique Chronic obstructive pulmonary disease (COPD) is a disease characterized by airflow limitation that is not fully reversible, progressive, and associated with abnormal inflammatory responses of the lungs to noxious gases or particles. With the progression of COPD, peripheral airway obstruction, pulmonary parenchymal destruction, and pulmonary vascular abnormalities reduce lung gas exchange capacity, resulting in hypoxemia, and hyperrespiratory acidemia may occur later. Blood gas analysis is very important for patients with acute and advanced COPD. However, the invasive nature of its operation not only increases the suffering of patients and the workload of medical staff, but also lacks rapidity and intu...

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Problems solved by technology

And create a simple and portable one that can better reflect the real PaCO 2 , especially the end-tidal carbon dioxide monitoring instrument that can truly reflect COPD patients. At present, there are no reports of similar experiments in the literature at home and abroad.

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