41 results about "Copd patients" patented technology

Devices and systems provide methods of detecting a severity change in respiratory insufficiency (RI) or chronic obstructive pulmonary disease (COPD) condition of a patient and in an exemplary embodiment, a detection monitoring device determines one or more severity change indicators based on a measure of supplied pressure or other representative measure determined by the device. The supplied pressure may optionally be determined during pressure treatment that satisfies a target ventilation. The supplied pressure or representative data may be compared to one or more thresholds that are selected to represent a change in the condition of the RI or COPD patient such as an exacerbation of a prior condition. Results of the comparisons may trigger one or more warnings or messages to notify a patient or physician of a pending change to the patient's RI or COPD condition so that the patient may more immediately seek medical attention to treat the condition.

Handheld medical diagnostic instrument that provides high time-resolution pulse waveforms associated with multiple parameters including blood pressure measurements, blood oxygen saturation levels, electrocardiograph (ECG) measurements, and temperature measurements. The device stores and analyzes the pulse waveforms simultaneously obtained from all tests, and thereby allows an unusually detailed view into the functioning of the user's cardiovascular heart-lung system. The device is designed for use by unskilled or semi-skilled users, thus enabling sophisticated cardiovascular measurements to be obtained in a home environment. Data from the device can be analyzed onboard, with local computerized devices, and with remote server based systems. The remote server may be configured to analyze this data according to various algorithms chosen by the physician to be most appropriate to that patient's particular medical condition (e.g. COPD patient algorithms). The server may be further configured to automatically provide alerts and drug recommendations.

Handheld medical diagnostic instrument that provides high time-resolution pulse waveforms associated with multiple parameters including blood pressure measurements, blood oxygen saturation levels, electrocardiograph (ECG) measurements, and temperature measurements. The device stores and analyzes the pulse waveforms simultaneously obtained from all tests, and thereby allows an unusually detailed view into the functioning of the user's cardiovascular heart-lung system. The device is designed for use by unskilled or semi-skilled users, thus enabling sophisticated cardiovascular measurements to be obtained in a home environment. Data from the device can be analyzed onboard, with local computerized devices, and / or with remote server based systems. The device or remote server may be configured to analyze this data according to various algorithms chosen by the physician to be most appropriate to that patient's particular medical condition (e.g. COPD patient algorithms). The device or remote server may be further configured to automatically provide alerts and drug recommendations.

The invention discloses a preparation method of clinical-grade autologous bronchial basal layer cells and application of a corresponding clinical-grade autologous bronchial basal layer cell reinfusion preparation in treatment of chronic obstructive pulmonary disease (COPD). The preparation method comprises the following steps: taking an in-vitro active bronchus brush inspection tissue, carrying out digestion treatment, and collecting cells after stopping digestion; and carrying out planking culture on the digested cells by using a culture plate paved with trophoblast cells, collecting the cells, carrying out multiplication culture on the cells by using the culture plate paved with trophoblast cells, and carrying out subculture when the cells grow to 50-90% of the surface area of the culture plate. Clinical-grade cells suitable for lung injury repair are determined for the first time, industrial preparation of the cells is achieved through the preparation process, bronchial basal layer cells meeting the clinical cell treatment number and quality can be obtained in a short time, the bronchial basal layer cells prepared through the method can be stably differentiated after entering the focus, and the treatment effect is good. The repair of the lung injury of the COPD patient is realized, and the lung function indexes such as FEV1, FEV1 / FVC, DLCO, MMEF and MVV are improved.

The present invention provides methods of treating a mammal having chronic obstructive pulmonary disease (COPD), independent of both smoking status and asthma status, with a therapeutically effective amount of an anti-IgE moiety. In accordance with the invention, COPD patients with an elevated serum IgE level may benefit from the treatment methods disclosed. In certain instances, the methods of the disclosure have been found to be useful for the treatment of COPD patients regardless of their skin test results and / or in vitro reactivity to a perennial aeroallergen. Anti-IgE moieties, in accordance with the invention, include but are not limited to any IgG antibody that selectively binds to a given mammal immunoglobulin E (e.g., human immunoglobulin E) such as humanized anti-IgE, humanized murine monoclonal antibody, and / or Omalizumab.

The invention provides traditional Chinese medicine composition for treating the stationary-phase COPD (chronic obstructive pulmonary disease). The composition comprises raw materials in parts by weight as follows: 47 parts of codonopsis radix, 59 parts of light wheat, 35 parts of fried largehead atractylodes rhizome, 23 parts of prepared pinellia tuber, 47 parts of dried tangerine peel, 35 parts of perilla fruit, 35 parts of divaricate saposhnikovia root, 35 parts of poria cocos, 59 parts of raw coix seed, 35 parts of honey-fried common coltsfoot flower, 35 parts of baical skullcap root, 35 parts of bulbus fritillariae pallidiflorae and 35 parts of honey-fried loquat leaf. The traditional Chinese medicine composition can prolong the second-time acute exacerbation time interval of a COPD patient by 77.68 days, decrease acute exacerbation times by 1.46 times per half a year, shorten the acute exacerbation duration by 2.93 days, decrease mMRC and CAT scores, improve clinical symptoms such as coughing, expectoration, shortness of breath, spontaneous perspiration, lacking in strength and the like, and enhance the exercise tolerance (that is, the 6MWD is increased). The composition has no side effect in a taking process of the clinical patient, so that the composition is a safe and effective prescription for treating the stationary-phase COPD.

The invention provides a method for predicting chronic obstructive pulmonary disease based on reconstructed airway tree images, and relates to the technical field of medical image processing. The method first collects multi-slice CT image files of COPD patients and healthy people from the same hospital, generates reconstructed airway tree images of healthy people and COPD patients, and converts different perspectives to generate reconstructed airway tree images of healthy people and COPD patients. Take a screenshot of the airway tree image, then remove the redundant background information of the intercepted airway tree image, and perform training and classification based on the convolutional neural network to predict whether someone has COPD in the test set; finally, reconstruct the image set intercepted by the airway tree Cross-validation ensures the accuracy of the prediction results. The COPD prediction method based on the reconstructed airway tree image provided by the present invention will be used as a technical means for preliminary screening of the disease, which is accurate and efficient, and effectively avoids misdiagnosis and missed diagnosis; meanwhile, it also eliminates the need for lung function tests. The complex process greatly reduces the workload of the hospital.