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A kind of traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease

A chronic obstructive, stable technology, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of complex preparation process of decoction, gastrointestinal irritation, no clear curative effect, etc., to achieve easy carrying and taking, good taste Good, no irritating effect

Active Publication Date: 2017-12-29
HUBEI BIO PHARMA IND TECHCAL INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no definite curative effect of the drugs for the treatment of COPD in the stable stage, and there are no therapeutic drugs that have undergone formal clinical trials on the market. The traditional Chinese medicines currently used in the clinical treatment of COPD in the stable stage are mostly decoctions and non-decoction powders , the preparation process of the decoction is complicated, and the taste is bitter and astringent when taken, the taste is poor, and it has certain irritation to the gastrointestinal tract

Method used

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  • A kind of traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease
  • A kind of traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease
  • A kind of traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease

Examples

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Effect test

Embodiment 1

[0248] A traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease of the present invention consists of the following raw materials in parts by weight:

[0249] 30 parts of Codonopsis, 30 parts of floating wheat, 30 parts of Stir-fried Atractylodes macrocephala, 10 parts of French Pinellia 10 parts, 30 parts of dried tangerine peel, 10 parts of Perilla Seed, 30 parts of Parsnip, 30 parts of Poria coix, 30 parts of Raw Coix Seed, 30 parts of Honey Coltsfoot, 30 parts of Scutellaria baicalensis Georgi, 30 parts of Ibei mother, 30 parts of honey loquat leaves.

[0250] The production process is as follows: the above 13 flavors, take the formula amount of Codonopsis pilosula, parsnip, and ibei mother to crush into fine powder, pass a 100-mesh sieve, and then take a small amount of it and pass a 120-mesh sieve for glazing. The rest of the floating wheat etc. Soak 8 times the amount of water in Weijia for 45 minutes, then decoct three times for 1 ...

Embodiment 2

[0253] A traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease of the present invention consists of the following raw materials in parts by weight:

[0254] 60 parts of Codonopsis, 70 parts of floating wheat, 60 parts of Fried Atractylodes, 30 parts of French Pinellia 30 parts, 60 parts of dried tangerine peel, 50 parts of Perilla Seed, 60 parts of Parsnip, 60 parts of Poria coix, 60 parts of Raw Coix Seed, 60 parts of Honey Coltsfoot, 60 parts of scutellaria baicalensis Georgi, 60 parts of Ibei mother, 60 parts of honey loquat leaves.

[0255] The production process is as follows: the above 13 flavors, take the formula amount of Codonopsis pilosula, parsnip, and ibei mother to crush into fine powder, pass a 100-mesh sieve, and then take a small amount of it and pass a 120-mesh sieve for glazing. The rest of the floating wheat etc. Soak 10 times the amount of water for 40 minutes, then decoct 3 times, 1 hour each time, combine the decoct...

Embodiment 3

[0258] A traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease of the present invention consists of the following raw materials in parts by weight:

[0259] 45 parts of Codonopsis, 75 parts of floating wheat, 45 parts of Fried Atractylodes, 20 parts of French Pinellia, 45 parts of dried tangerine peel, 40 parts of Perilla Seed, 40 parts of Parsnip, 40 parts of Poria coix, 40 parts of Raw Coix Seed, 40 parts of Honey Coltsfoot, 40 parts of Scutellaria baicalensis Georgi, 40 parts of Ibei mother, 40 parts of honey loquat leaves.

[0260] The production process is as follows: the above 13 flavors, take the formula amount of Codonopsis pilosula, parsnips, and ibei mother to crush into fine powder, pass a 100-mesh sieve, and then take a small amount from it, pass the 120-mesh sieve, and use it for polishing. Soak 12 times the amount of water in Weijia for 30 minutes, then decoct 3 times, 1 hour each time, combine the decoction, filter, and co...

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Abstract

The invention provides traditional Chinese medicine composition for treating the stationary-phase COPD (chronic obstructive pulmonary disease). The composition comprises raw materials in parts by weight as follows: 47 parts of codonopsis radix, 59 parts of light wheat, 35 parts of fried largehead atractylodes rhizome, 23 parts of prepared pinellia tuber, 47 parts of dried tangerine peel, 35 parts of perilla fruit, 35 parts of divaricate saposhnikovia root, 35 parts of poria cocos, 59 parts of raw coix seed, 35 parts of honey-fried common coltsfoot flower, 35 parts of baical skullcap root, 35 parts of bulbus fritillariae pallidiflorae and 35 parts of honey-fried loquat leaf. The traditional Chinese medicine composition can prolong the second-time acute exacerbation time interval of a COPD patient by 77.68 days, decrease acute exacerbation times by 1.46 times per half a year, shorten the acute exacerbation duration by 2.93 days, decrease mMRC and CAT scores, improve clinical symptoms such as coughing, expectoration, shortness of breath, spontaneous perspiration, lacking in strength and the like, and enhance the exercise tolerance (that is, the 6MWD is increased). The composition has no side effect in a taking process of the clinical patient, so that the composition is a safe and effective prescription for treating the stationary-phase COPD.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating stable chronic obstructive pulmonary disease. Background technique [0002] Chronic obstructive pulmonary disease (COPD) is a disease characterized by airflow limitation. COPD patients accounted for 3% of people aged 15 years and over in my country. It is the first cause of death in rural areas and the first in the World Health Organization’s assessment of the burden of disease in my country. Bit. Studies by the World Bank and WHO show that COPD was the 12th most lethal and disabling disease in the world in 1990, but it will become the 3rd most lethal and disabling disease in the world by 2020. Although countries all over the world have invested a lot of manpower and material resources in COPD research, and formulated corresponding diagnosis and treatment standards, the prevalence, mortality, and disability rate of COPD and the resulting burden of disease in the family and soci...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P11/00
CPCA61K9/20A61K36/076A61K36/238A61K36/28A61K36/284A61K36/344A61K36/535A61K36/539A61K36/73A61K36/752A61K36/8888A61K36/8966A61K36/899A61K36/8994A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 李风森张艳丽李争高振徐丹荆晶徐倩
Owner HUBEI BIO PHARMA IND TECHCAL INST
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