Application of capparis spinosa in preparing medicaments for treating kidney disease

A kidney disease, mallet vine technology, applied in the field of herbal medicine, can solve the problems of unsatisfactory curative effect of FSGS

Inactive Publication Date: 2008-08-06
应旭旻
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Overall, the curative effect of FSGS is still unsatisfactory, and it i

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0129] Preparation of decoction

[0130] Weigh 12kg vine and add 10 times of water to soak for half an hour, heat, boil the water to extract for 45 minutes, filter, discard the filter residue, set the volume to 1000ml, and obtain a decoction equivalent to the concentration of the original medicinal material at 12g / ml.

Embodiment 2

[0132] Preparation of granules

[0133] Weigh 6kg vine and add 8 times water to soak for half an hour, heat, boil water for extraction for 45 minutes, filter, discard the filter residue, concentrate the filtrate to a clear paste with a relative density of 1.38-1.40 (60°C), take the clear paste and add sucrose The weight ratio (1:2) of the mixture of powder and starch is appropriate, mix well, add appropriate amount of ethanol to make 1000g of granules, and pack in 10g per bag.

Embodiment 3

[0135] Tablet preparation

[0136] Weigh 3 kg of vine and add 9 times water to soak for half an hour, heat, boil water and extract for 60 minutes, filter, discard the filter residue, concentrate the filtrate to a clear paste with a relative density of 1.38-1.40 (60°C), take the clear paste and add Appropriate amount of cyclodextrin, made into granules, added appropriate amount of talcum powder, and pressed into tablets to obtain 1000 tablets.

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PUM

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Abstract

The invention discloses a use of capparis spinosa in preparing drugs for treating kidney diseases, in particular to an application in preparing drugs for treating focal segmental glomerulus sclerosis. The invention explains the action mechanism of the medicine through the therapeutic effects of capparis spinosa on the focal segmental glomerulus sclerosis of rat models and the initial screening of gene chips, and shows remarkable curative effect on kidney diseases through the clinical experiment of the medicine prepared by capparis spinosa, in which no side effects as bone marrow suppression, liver damage and so on are found, thus being proved to have a broad application prospect.

Description

technical field [0001] The present invention relates to a new application of a herbal medicine, in particular to a new application of a botanical vine in the treatment of kidney diseases, in particular to the use of the plant in the preparation of focal segmental kidney disease. Use in glomerular sclerosing medicines. Background technique [0002] Kidney disease is a common disease that endangers public health. According to the latest clinical epidemiological survey, the incidence of chronic kidney disease in my country is close to 10%. The continuous progression of various chronic kidney diseases will lead to chronic renal failure and patients must be kept alive by long-term renal replacement therapy (dialysis or transplantation). At present, the total number of people receiving dialysis treatment in our country is hundreds of thousands, and it is still increasing at a rate of more than 10% every year. Each dialysis patient spends more than 100,000 yuan per year in treatm...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P13/12A61K131/00
Inventor 应旭旻
Owner 应旭旻
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