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Micrometre level arachidonic acid/docosahexaenoic acid emulsion and preparation thereof

A technology of carbhexaenoic acid emulsion and docosahexaenoic acid, which is applied in the directions of emulsion delivery, food preparation, pharmaceutical formula, etc., can solve the problem of difficult infant formula food, no product release, and inability to withstand high temperature and other problems, to achieve the effect of simple and feasible production process, simplified production and processing technology, and energy saving

Active Publication Date: 2010-06-02
湖北福星生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] ARA / DHA oil is easily oxidized when exposed to air, and cannot withstand high temperature, so it is difficult to directly use it in infant formula under the condition of effectively maintaining its activity
Judging from the currently published patents, there is only a production and application method for a single product in ARA or DHA, but there is no publication of a product after an effective ratio of ARA / DHA

Method used

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  • Micrometre level arachidonic acid/docosahexaenoic acid emulsion and preparation thereof

Examples

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preparation example Construction

[0051] In the preparation method of the emulsion, at least two pressure homogenizations are required, and at least one homogenization pressure is above 200 MPa.

[0052] The particle size of the obtained emulsion is less than 1 micron, and the water is deionized water.

[0053] The micron-sized arachidonic acid / docosahexaenoic acid emulsion is used in medicine, cosmetics, health care products and food, and is directly added or used together with other ingredients, and the added amount accounts for 0.15-7.5% of the total weight.

[0054]Arachidonic acid / docosahexaenoic acid (ARA / DHA) emulsion example:

Embodiment 1

[0055] Embodiment 1 contains the preparation of ARA / DHA50g / kg (ARA: DHA=2: 1) emulsion:

[0056] Take by weighing 90 grams of mixed oil of 40% arachidonic acid content, 50 grams of 35% DHA oil, 0.1 gram of antioxidant (comprising natural vitamin E 0.04 gram, ascorbyl palmitate 0.04 gram, rosemary 0.02 gram), 10 grams of oil phase emulsifier (including 5 grams of lecithin and 5 grams of polyglycerol ester), mix them while heating, and when the temperature rises to 60 ° C, immediately transfer to the water phase (water phase temperature 75 ° C, chemical material 40 min , then cooled to 60°C), 5 grams of aqueous phase emulsifier in the water phase (including 2 grams of diacetyl tartrate fatty acid glycerides, 3 grams of Tween 80), 10 grams of dispersant (including 10 grams of glucose) and thickening stabilizer 100 grams (including 20 grams of sodium carboxymethylcellulose and 80 grams of cyclodextrin), supplemented with deionized water to a total of 1000 grams. Slowly add, stir ...

Embodiment 2

[0057] Embodiment 2 preparation containing ARA / DHA50g / kg (ARA: DHA=3: 1) emulsion:

[0058] Take by weighing 93.8 grams of mixed oil with 40% arachidonic acid content, 35.8 grams of 35% DHA oil, 5.05 grams of antioxidants (including 2 grams of natural vitamin E, 2 grams of ascorbyl palmitate, 1.05 grams of rosemary), oil phase 55 grams of emulsifier (including 22.5 grams of lecithin and 22.5 grams of polyglycerol ester), they are mixed while heating, and when the temperature rises to 60 ° C, they are immediately transferred to the water phase (the water phase temperature is 75 ° C, the material is 40 min, and then Cooled to 60°C), 22.5 grams of aqueous phase emulsifiers in the water phase (including 9 grams of diacetyl tartrate fatty acid glycerides, 13.5 grams of Tween 80), 55 grams of dispersants (including 55 grams of glucose) and 200 grams of thickening stabilizers (comprising 40 grams of sodium carboxymethylcellulose and 160 grams of cyclodextrin), supplemented with deion...

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Abstract

The invention discloses an emulsion of micron-sized arachidonic acid (ARA) / docosahexenoic acid (DHA) and a preparation method thereof. The emulsion comprises 50g to 150g of ARA and DHA (the ratio of ARA to DHA is 2 to 4), 10g to 100g of oil phase emulsifier, 0.1g to 10g of antioxidant, 5g to 40g of aqueous phase emulsifier, 100g to 300g of thickening and stabilizing agent and 10g to 100g of dispersant; water is added until the solution is 1000g. The emulsion of the invention is O / W type and mainly characterized in that the emulsifiers and the thickening and stabilizing agent are emulsified with the ARA / DHA and water according to certain proportions so as to obtain the emulsion with stable status and emulsified particle diameter less than 1 micron. The invention aims at providing a prescription of an ARA / DHA emulsion which is reasonable in nutrition-allocated proportion and capable of dispersing in cold water, provided with good stability and is stable against light, heat and oxygen andcan be conveniently used in beverage and other relevant industries.

Description

technical field [0001] The invention relates to a micron-sized arachidonic acid and docosahexaenoic acid emulsion and a preparation method thereof, especially an arachidonic acid / eicosahexaenoic acid that needs to be used in food, medicine, health care products and cosmetics industries The formulation, process and application of dicosahexaenoic acid (ARA / DHA) emulsion. The product of the present invention is used as a nutrition fortifier. Background technique [0002] Arachidonic acid (ARA) and docosahexaenoic acid (DHA) belong to the n-6 and n-3 fatty acid series, which are synthesized from linoleic acid and a-linolenic acid respectively. Studies have found that during the embryonic and infant stages of growth and development, a large amount of ARA / DHA accumulates in the brain and other tissues, that is, sufficient DHA and ARA are needed during the embryonic and infant stages. The ARA / DHA required by the fetus must be supplied by the mother through the placenta. Preterm ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/36A61K31/202A23L1/30A61P3/02A61K9/107A23L33/12
Inventor 宁超美解秀娟李莹胡锐
Owner 湖北福星生物科技有限公司
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