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Application of saxifrage for preparing medicaments for treating hyperplasia of mammary glands, lipoma and thyroid gland carcinoid

A technology for mammary gland hyperplasia and benign tumors, which can be applied to antineoplastic drugs, drug combinations, diseases, etc., and can solve problems such as lack of curative effect

Active Publication Date: 2009-06-03
朱彤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Similarly, the existing drugs for the treatment of lipoma and thyroid tumors are deficient in curative effect and other aspects.

Method used

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  • Application of saxifrage for preparing medicaments for treating hyperplasia of mammary glands, lipoma and thyroid gland carcinoid
  • Application of saxifrage for preparing medicaments for treating hyperplasia of mammary glands, lipoma and thyroid gland carcinoid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0083] Embodiment 1: the preparation of injection:

[0084] The saxifrage raw material of 100% weight component is weighed.

[0085] Soak in water for a day. Decoct twice, each time for 2 hours, combine the filtrate, concentrate, add 95% ethanol while hot, and make the ethanol content reach 85%. Stand still and refrigerate for one day, and filter to obtain the extract; or weigh the saxifrage raw material of 100% by weight. Soak twice with 70% to 95% alcohol, each time for 7 days, combine the filtrate and filter. Ethanol is recovered by distillation to obtain extract. Get described medicinal extract, carry out ethyl acetate extraction four times with the routine method of making Chinese medicine preparation; Anti-oxidize above-mentioned recovery liquid with sodium sulfite with the conventional method of making Chinese medicine preparation, and advance acid-base balance with the conventional method of making Chinese medicine preparation, Adjust the pH value to between 3.1 an...

Embodiment 2

[0086] Embodiment 2: the preparation of suppository:

[0087] The saxifrage raw material of 100% weight component is weighed.

[0088] Soak in water for a day. Decoct twice, each time for 2 hours, combine the filtrate, concentrate, add 95% ethanol while hot, and make the ethanol content reach 85%. Keep it refrigerated for one day, and filter to obtain the extract. Or take the saxifrage raw material of 100% weight component. Soak twice with 70% to 95% alcohol, each time for 7 days, combine the filtrate and filter. Ethanol is recovered by distillation to obtain extract. Take the extract and add excipient polyethylene glycol or palmitic acid ester, and then artificially shape to obtain the finished product.

Embodiment 3

[0089] Embodiment 3: the preparation of oral agent

[0090] The saxifrage raw material of 100% weight component is weighed.

[0091] Soak in water for a day. Decoct twice, each time for 2 hours, combine the filtrate, concentrate, add 95% ethanol while hot, and make the ethanol content reach 85%. Keep it refrigerated for one day, and filter to obtain the extract. Or take the saxifrage raw material of 100% weight component. Soak twice with 70% to 95% alcohol, each time for 7 days, combine the filtrate and filter. Ethanol is recovered by distillation to obtain extract. Take the extract and add excipient polyethylene glycol or palmitate, and then spray, flake, pack into hard capsules, etc. to get the finished product.

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Abstract

The invention discloses an application of saxifrage for preparing medicaments for treating hyperplasia of mammary glands, lipoma and thyroid gland carcinoid. The medicaments for the treating hyperplasia of mammary glands, the lipoma and the thyroid gland carcinoid have good effect. An acute and sub-acute toxicity experiment shows that the medicament has no toxic and side effect.

Description

Technical field: [0001] The invention relates to a new application of medicine, which is the application of saxifrage in the preparation of medicine for treating mammary gland hyperplasia, lipoma and thyroid benign tumor. Background technique: [0002] Mammary gland hyperplasia (called breast addiction in traditional Chinese medicine) is a common non-inflammatory non-tumor disease in women, accounting for about 75% of all breast diseases, and the incidence rate can reach 47% in women of childbearing age. Some atypical hyperplasia is considered to be the cause of breast cancer. borderline disease. With changes in work and lifestyle, the incidence of this disease has been increasing in recent years, and its incidence is mainly related to female hormone disorders. At present, symptomatic treatment is mainly used, and hormone therapy and endocrine therapy are used. The commonly used ones are: tamoxifen, thyroid hormone preparations, bromocriptine, danazol, and sex hormones. We...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P15/14A61P35/00
Inventor 居龙涛
Owner 朱彤
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