Blood treatment filter and blood treatment circuit

A blood treatment and filter technology, applied in blood transfusion devices, suction devices, etc., can solve the problem of inability to prepare platelet preparations, and achieve the effects of good operation efficiency, sufficient removal rate, and sufficient recovery rate

Active Publication Date: 2009-06-17
TERUMO KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commercially available filters for whole blood preparations remove not only white blood cells but also highly adherent platelets, so it is practically impossible to prepare platelet preparations

Method used

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  • Blood treatment filter and blood treatment circuit
  • Blood treatment filter and blood treatment circuit
  • Blood treatment filter and blood treatment circuit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～17

[0108] in such as figure 1 , 2 The housing of the shape shown in the figure is composed of a polycarbonate cover and a bottom to accommodate a filter unit, the filter unit uses a polyether type polyurethane sponge-like porous membrane as the main filter unit, and a polyether type polyurethane filter unit is used. A sponge-like porous membrane made of polyurethane was used as the pre-filter part, and each edge was high-frequency welded, and the edge of the case was high-frequency welded from the outside to manufacture a blood processing filter. Here, make the effective area of ​​the filter part excluding the welded part (part without filter function) 50 cm 2 And manufacture.

Embodiment 18

[0110] in such as figure 1 , 2 The housing of the shape shown in the figure is composed of a polycarbonate cover and a bottom, and a filter unit is housed inside, and the filter unit is made of a polyethylene terephthalate non-woven fabric with an average fiber diameter of 1.2 μm. Cloth is used as the main filter part, polyether polyurethane sponge-like porous membrane is used as the pre-filter part, and the edges of each are high-frequency welded, and the edges of the case are high-frequency welded from the outside, thereby Manufacture of blood processing filters. Here, make the effective area of ​​the filter part excluding the welded part (part without filter function) 50 cm 2 And manufacture.

[0111] In addition, the surface of the main filter unit was covered with a copolymer composed of 2-hydroxyethyl methacrylate (HEMA) and dimethylaminoethyl methacrylate (DM).

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Abstract

Blood treatment filter (1) having housing (2) provided with inflow port (4) and outflow port (6) and, placed in the housing (2), filter unit (7) for filtering of blood containing erythrocytes, platelets and leukocytes as blood cell components, characterized in that the filter unit (7) includes a main filter part capable of substantially trapping preselected blood cell components from blood while allowing the remainder of the blood cell components to pass therethrough and a prefilter part disposed upstream of the main filter part and structured to trap substantially no blood cell components, and that the prefilter part exhibits a microparticle transmission ratio of 70 to 90% as measured by causing a suspension containing microparticles of 6 [mu]m average particle diameter to flow with a drop distance.

Description

technical field [0001] The present invention relates to a blood treatment filter and a blood treatment circuit for preparing blood component preparations for blood transfusion. Background technique [0002] In recent years, blood component preparations from which leukocytes causing side effects have been removed have been widely used when blood component preparations are transfused. As a method of removing leukocytes from blood component preparations, it is roughly divided into centrifugation of blood collected from a blood donor (whole blood preparation), preparing each blood component, filtering each blood component using a filter suitable for each blood component, and removing leukocytes. Method: use a filter to filter the whole blood preparation to remove leukocytes, centrifuge and prepare the blood component preparation. [0003] Currently commercially available filters for whole blood preparations remove not only leukocytes but also highly adherent platelets, so it is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02
CPCA61M2001/0222A61M1/3633A61M1/0209A61M1/0222A61M1/0231A61M1/0236
Inventor 今井正大河原顺一村越正英
Owner TERUMO KK
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