Marker for function check of stomach and intestine and preparation method thereof

A technology of gastrointestinal function and markers, applied in the direction of X-ray contrast agent preparation, etc., can solve the problems affecting the accuracy of inspection results, etc., and achieve the effect of good promotion and practical value, accurate inspection results, and easy production and manufacturing

Inactive Publication Date: 2010-09-15
莱芜钢铁集团有限公司医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Specifically, all examinations will inevitably have a certain impact on the function of the gastrointestinal tract, which we should try our best to avoid in the examination, otherwise, it will affect the accuracy of the examination results

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036]Medical barium sulfate 1000 grams, glucomannan 15 grams, edible alkali 10 grams, water 100ml. Dissolve glucomannan in water, stir and heat. After the solution boils, add 10 grams of edible alkali into 10ml of water to dissolve, pour into the glucomannan solution and stir, then add barium sulfate, and adjust it into a dough-like structure. Then it is processed and cut to make a granular structure with a diameter of 2 mm, and then it is dried, and the dried particles are packed into capsules.

[0037] The size of each capsule is 3X5mm, and a single capsule weighs about 2 grams after being filled with medicine. 1000 grams of barium sulfate products are about 500 capsules. During the inspection, each patient takes 10 capsules (about 20 grams) orally, to achieve the inspection purpose, and the medicine prepared according to the above requirements can be used for the inspection of 50 person-times.

Embodiment 2

[0039] Medical barium sulfate 450 grams, glucomannan 6 grams, edible alkali 4 grams, water 50ml. Dissolve glucomannan in water, stir and heat. After the solution boils, add 4 grams of edible alkali into 10ml of water to dissolve, pour into the glucomannan solution and stir, then add barium sulfate, and adjust it into a dough-like structure. Then it is processed and cut to make a granular structure with a diameter of 2 mm, and then it is dried, and the dried particles are packed into capsules.

[0040] The size of each capsule is 3X5mm, and a single capsule weighs about 2 grams after being filled with medicine. 450 grams of barium sulfate products are about 230 capsules. During the inspection, each patient takes 10 capsules (about 20 grams) orally, to achieve the inspection purpose, and the medicine prepared according to the above requirements can be used for the inspection of 23 person-times.

Embodiment 3

[0042] 750 grams of medical barium sulfate, 7 grams of glucomannan, 6 grams of edible alkali, and 60 ml of water. Dissolve glucomannan in water, stir and heat, after the solution boils, add 6 grams of edible alkali into 10ml water to dissolve, pour into the glucomannan solution and stir, then add barium sulfate, adjust it into a dough-like structure, Then it is processed and cut to make a granular structure with a diameter of 2 mm, and then it is dried, and the dried particles are packed into capsules.

[0043] The size of each capsule is 3X5mm, and the weight of a single capsule is about 2 grams after being filled with medicine, and the finished product of 750 grams of barium sulfate is about 380 capsules. During the inspection, each patient takes 10 capsules (about 20 grams) orally, to achieve the inspection purpose, and the medicine prepared according to the above requirements can be used for the inspection of 38 person-times.

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PUM

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Abstract

The invention relates to the preparation of a medicine which is used special for the examination of gastrointestinal tract functions of human bodies and can develop under X rays after the oral administration. The medicine is formed by adding an X ray material [B] with high dilatability, high viscosity and low absorption during the preparation, a material [C] which plays a role in solidification and agglomeration, and water [D] into a contrast agent, wherein the contrast agent takes metal salts (such as barium sulfate, and the like) [A] which have no toxicity, are not absorbed by the human bodies, and have high atomic number as main materials; and [A]+[B]+[C]+[D] is equal to 50-99%+0.5-10%+0.5-5%+1-40%=100%(w / w). The invention has the advantages of reasonable design formulation, economy and practicality, safe oral administration, no toxic and side effect, and accurate and reliable detection result, cannot produce a false negative or false positive result, has the characteristics of synchronously having morphology and function, and can provide an advantageous evidence for clinical diagnosis and treatment.

Description

Technical field [0001] The invention belongs to the technical field of preparations for human body tests, and specifically relates to a medicine which can be developed under X-ray after oral administration and is specially used for checking the dynamic function and digestion and decomposition ability of human digestive tract and its preparation method. Background technique [0002] The function of the human gastrointestinal tract includes two aspects: dynamic emptying and digestion and absorption. At present, there have been research reports on the detection of gastrointestinal emptying ability, but due to certain limitations, it has not been widely used in clinical practice. , The digestion and absorption function of the gastrointestinal tract is based on the premise of the grinding and digestion of food by the gastrointestinal tract. It can be expressed by its ability to digest food. However, we have also not found any research and application on human gastrointestinal di...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/04
Inventor 牟健民孟桂兰王世东谭乐成张盈张玉民苏明杰牟童
Owner 莱芜钢铁集团有限公司医院
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