Flexible micro-electrode chip stimulating visual cortex through dura mater and the preparation method thereof

A micro-electrode and dura mater technology, applied in the field of flexible micro-electrode chips and preparation, can solve problems such as high price, achieve good symmetry, improve anti-oxidation and anti-corrosion properties, and ensure the effect of implementation and control

Inactive Publication Date: 2009-10-07
ARMY MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Its characteristic is to ensure the flexible processing of various materials, but the price is relatively expensive

Method used

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  • Flexible micro-electrode chip stimulating visual cortex through dura mater and the preparation method thereof
  • Flexible micro-electrode chip stimulating visual cortex through dura mater and the preparation method thereof
  • Flexible micro-electrode chip stimulating visual cortex through dura mater and the preparation method thereof

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Embodiment Construction

[0042] Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. It should be understood that the preferred embodiments are only for illustrating the present invention, but not for limiting the protection scope of the present invention.

[0043] like figure 1 As shown, the flexible microelectrode chip of the present invention stimulates the visual cortex through the dura mater, and the chip includes a flexible polymer substrate 1, a microelectrode array 2 composed of several microelectrodes 5 and a solder joint formed by several solder joints 7. Point array 3 , the microelectrode array 2 is arranged on the flexible polymer substrate 1 , and the pins of the microelectrodes 5 are connected to the welding spots 7 through metal leads 9 in a one-to-one correspondence.

[0044] The flexible polymer substrate 1 should be polyimide, polydimethylsiloxane or parylene and other materials that are soft, transparen...

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Abstract

The invention discloses a flexible micro-electrode chip stimulating visual cortex through dura mater and the preparation method thereof. The chip includes a flexible polymer substrate, a micro-electrode array composed of several micro-electrodes and a weld spot array formed by combining several weld spots, wherein, the micro-electrode array is provided on the flexible polymer substrate, and the pin of the micro-electrodes is in one-to-one correspondence connection to the weld spots through metal wires. the invention uses electric stimulation signal applied on the micro-electrodes arranged in the micro-electrode array to stimulate visual cortex below the dura mater, so that the patient generates optical illusion, the chip has good biocompatibility and stability integrally, and also has excellent electrical conductivity, and may greatly reduce the damage to the tissue in the chip implantation process or after the chip implantation process, the processing cost of the flexible circuit board is lower than the other ways, the security of the stimulating method is higher than general implantation methods, and the invention can be widely used in visual rehabilitation and repair field.

Description

technical field [0001] The invention relates to a flexible microelectrode chip for stimulating the visual cortex through the dura mater and its preparation method. The microelectrode chip is designed based on the principle that stimulating the visual cortex below the dura mater with an electrical stimulation signal will cause phosphenes in patients, and belongs to biomedical engineering. Intersection with microchip systems. Background technique [0002] According to the report of the World Health Organization, more than 160 million people around the world suffer from varying degrees of vision impairment, of which about 45 million people suffer from blindness. Clinical data show that retinal degenerative diseases, such as retinitis pigmentosa (Rtinitis Pigmentosa, RP), age-related macular degeneration (Age-Related macularDegeneration, AMD), etc., are the main diseases causing blindness. People try multiple methods such as operation and medicine to help patients recover their...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/02
Inventor 阴正勤侯文生陈丽峰胡宁郭冰冰刘娜夏露
Owner ARMY MEDICAL UNIV
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