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Chinese medicament preparation for protecting DNA oxidative damages, preparation method and application thereof

A traditional Chinese medicine preparation, oxidative damage technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, antidote, etc., to achieve diverse products, DNA oxidative damage protection and repair, and significant effects

Inactive Publication Date: 2011-05-18
柯跃斌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there are few existing studies on the protection of DNA oxidative damage, mainly focusing on the demonstration of the role of the first defense system, and almost no reports involving the use of molecular biomarker 8-OHdG of DNA oxidative damage

Method used

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  • Chinese medicament preparation for protecting DNA oxidative damages, preparation method and application thereof
  • Chinese medicament preparation for protecting DNA oxidative damages, preparation method and application thereof
  • Chinese medicament preparation for protecting DNA oxidative damages, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0039] Select the raw materials of following parts by weight among the embodiment of the present invention 1~9:

[0040] raw material

Example 1

Example 2

Example 3

Example 4

Example 5

Example 6

Example 7

Example 8

Example 9

Minoru Yama

60

40

35

32

50

57

30

45

55

ginkgo

35

30

37

40

25

20

34

28

32

Ganoderma lucidum

15

20

23

30

28

13

10

22

25

hemp seed

8

10

15

18

12

17

9

13

20

[0041] The preparation method of the traditional Chinese medicine preparation for the protection of DNA oxidative damage is as follows: select the dry products of the raw materials of the above-mentioned table, such as the dried products of sage, ginkgo, ganoderma, and hemp seed, and soak them in water for 30 minutes to 1 hour. Choose 30, 40, 50, 60 minutes to soak, first heat and boil the ganoderma lucidum for 20-30 minu...

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Abstract

The invention discloses a Chinese medicament preparation for protecting DNA oxidative damages, a preparation method and application thereof. The Chinese medicament preparation is prepared from the following raw materials: rose myrtle seed, ginkgo, glossy ganoderma and fructus cannabis. The preparation method of the Chinese medicament preparation comprises the following steps: soaking the rose myrtle seed, the ginkgo, the glossy ganoderma and the fructus cannabis in water respectively; decocting the glossy ganoderma first, and then adding the other raw materials for decoction; filtering the decoction, and concentrating the filtrate; and filtering the decoction again to obtain a Chinese medicament crude extract for standby. The Chinese medicament preparation is favorable for improving the anti-DAN oxidation defense function of an organism in an oxidative stress state, has inoxidability, and can be prepared into anti-ageing medicaments and anti-cancer health products. The crude extract of the Chinese medicament preparation also serves as an active component which is combined with other acceptable adjuvant or carriers to form a novel anti-ageing health product with the anti-DAN oxidation function.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine preparation, a preparation method and an application thereof, in particular to a traditional Chinese medicine preparation for DNA oxidative damage protection, a preparation method and an application thereof. Background technique [0002] "DNA oxidative damage is the mother of all damage." Oxygen free radicals are produced every moment in the body's metabolism. According to reports, about 2% of the oxygen inhaled by the human body is converted into reactive oxygen species (ROS) in the body. Excessive The ROS can damage lipids, proteins, DNA and other biological macromolecules, and destroy the normal physiological process of the body. It is estimated that about 90% of diseases, including cancer, cardiovascular and cerebrovascular diseases, are related to free radicals. Hydroxyl free radicals and singlet oxygen can attack the guanin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/61A61P39/06
Inventor 柯跃斌
Owner 柯跃斌
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