Flavonoid compound and application of plant extract containing same

A technology of flavonoids and plant extracts, which is applied to flavonoids or plant extracts containing them in the field of medicine, can solve the problems of bone marrow suppression, high price of long-acting interferon, gastrointestinal symptoms and the like, and achieves less side effects, Good anti-hepatitis C virus effect
CN101744830AInactive Publication Date: 2010-06-23SHANGHAI INST OF PHARMA IND CO LTD +1
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI INST OF PHARMA IND CO LTD
Publication Date
2010-06-23
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a class of flavonoid compound as shown in formula I or an application of a plant extract containing the same in preparing medicine against hepatitis c virus, wherein R1, R2, R4, R5 and R6 are independently H, OH or OMe; R3 is H, OH, OMe or beta-D-gluconic acid; and a single bond or a double bond is arranged between a second carbon and a third carbon. The flavonoid compound has better effects of resisting the hepatitis c virus and less side effects, mostly comes from the traditional Chinese medicine and is cheap, safe and effective. Formula I.
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Description

technical field

[0001] The invention relates to a new application of a class of flavonoid compounds or plant extracts containing them in the field of medicine. Background technique

[0002] According to incomplete statistics, there are as many as 40 million hepatitis C antibody-positive patients in my country, and 80% of them will suffer from chronic hepatitis C. Hepatitis C is a liver disease that is transmitted through blood, sexual contact, mother to child and daily life contact. After HCV infection, like HBV infection, chronic hepatitis, liver cirrhosis and liver cancer are prone to occur.

[0003] Currently, long-acting interferon combined with ribavirin is mainly used to treat hepatitis C patients with normal liver function, and the overall sustained virological response rate is 52%. However, during the treatment of interferon and ribavirin, adverse reactions such as bone marrow suppression, emotional depression, and gastrointestinal symptoms may occur. Moreover, lo...

Claims

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