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Cachexia prevention supplement

A substance and dose technology, applied in the field of nutritional composition and nutritional supplements for the prevention and/or treatment of cachexia and/or anorexia, can solve the problems of difficulty and limited success rate of intervention methods for rebuilding muscle and fat mass

Inactive Publication Date: 2010-08-11
FRESENIUS KABI DEUT GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Interventional approaches to rebuild muscle and fat mass have proven difficult and have limited success once tissue loss is evident

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The nutritional composition of the present invention is prepared by mixing the components in the amounts described in Table 1. No encapsulation prior to mixing. The compositions described in Table 1 provide a calorific value of approximately 100 kcal. The amounts of the individual components correspond to 50% of the recommended daily dose, so the composition should be taken twice a day. Calorific value can be determined by suitable methods known in the art.

[0068] Table 1

[0069] Element

[0070] Element

[0071] The above composition is packaged into a sachet that provides a calorific value of about 100 kcal.

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PUM

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Abstract

The invention provides for a nutritional composition comprising from 0. 1 to 10 g of eicosapentaenoic acid or a derivative thereof based on 100 kcal of the total composition; and from 0. 1 to 10 g of a phytochemical or a mixture thereof based on 100 kcal of the total composition, for a use as a medicament for the treatment and / or prevention of cachexia and / or anorexia. The composition is particularly useful in the prevention of cachexia and is administered almost without any additional macronutrients in order to avoid a negative impact on the general diet of the patient.

Description

[0001] describe [0002] The present invention relates to a nutritional composition for preventing and / or treating cachexia and / or anorexia, preferably a nutritional supplement. The composition of the present invention comprises eicosapentaenoic acid or its derivatives and at least one phytochemical as components. In a preferred embodiment, the composition further comprises one or more branched-chain amino acids and / or glutamine in neutral or salt form or in the form of precursors or derivatives thereof. In a particularly preferred embodiment, the composition further comprises one or more additional antioxidants, such as mixed carotenoids, vitamin E, vitamin C, zinc, magnesium and selenium. Background technique [0003] Cachexia is manifested by a progressive loss of muscle and adipose tissue, with increased morbidity and mortality. The term is derived from the Greek words "kakos", meaning "poor", and "hexis", meaning "condition", generally understood as a state of being unh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L1/30A61K31/20A23L33/00A23L33/15
CPCA23V2002/00A61K31/20A23L1/302A61K31/202A23L1/3051A23L1/3008A23L1/3002A23L33/105A23L33/12A23L33/15A23L33/175A61P1/14A61P3/04A61P7/00A23V2250/187A23V2250/2132A23V2250/0654A23V2250/0628A23V2250/0626A23V2250/062A23V2250/211A23V2250/70A23V2250/708A23V2250/214
Inventor 施奈德·克里斯汀娜
Owner FRESENIUS KABI DEUT GMBH