Rodent oronasal suction dynamic exposing device

Abstract

The invention relates to a rodent oronasal suction dynamic exposing device, which is characterized in that the rodent oronasal suction dynamic exposing device comprises at least one section of combinable exposing chamber, wherein the exposing chamber comprises an outer tube and an inner tube positioned in the outer rube, a plurality of aerosol sampling pipes and a plurality of animal tube insertion nozzles are arranged on the tube wall of the outer tube, animal tubes are correspondingly inserted and arranged on the animal tube insertion nozzles, an aerosol suction pipe is respectively penetrated into each animal tube insertion nozzle, a top cover of the exposing chamber is arranged on the top of the highest section of the exposing chamber, the middle of the top cover is provided with a mixed aerosol air inlet, an aerosol air inlet pipe is connected above the air inlet, the air inlet end of the air inlet pipe is connected with an aerosol generator, the outer tube and the inner tube of the lowest section of the exposing chamber are respectively and correspondingly positioned on an outer tube base and an inner tube base, at least one circle of vent holes are arranged on the inner tube base arranged between the outer tube and the inner tube of the exposing chamber, an aerosol air outlet is arranged in the middle of the outer tube base, the air outlet is connected with an aerosol air outlet pipe, and the outlet end of the air outlet pipe is connected with an air pump. The invention has the advantages of ingenious structural design and convenient operation, and can be widely used in the animal suction test research process.

Description

technical field [0001] The invention relates to an animal test device, in particular to a dynamic exposure device for rodent mouth and nose inhalation. Background technique [0002] At present, in various scientific researches related to inhalation, especially the research on some substances harmful to human health, because they cannot be tested directly or firstly on humans, experimental animals are often used for inhalation exposure evaluation. Therefore, animal exposure devices are used in It has a wide range of applications in industry, agriculture, medicine and military scientific research. Animal exposure devices in the prior art can be roughly divided into three categories, namely: static exposure devices, cyclic exposure devices and dynamic exposure devices. [0003] A static exposure apparatus is an exposure apparatus in which there is no air flow in the exposure chamber. The main disadvantages of this exposure device are: 1) As the exposure time prolongs, the oxy...

AI Technical Summary

Problems solved by technology

The main disadvantages of this exposure device are: 1) as the exposure time prolongs, the oxygen concentration in the exposure chamber will gradually decrease, or even be exhausted; the temperature in the exposure chamber will increase

But there are also quite obvious disadvantages: 1) many test materials are consumed; 2) other parts of the body will also be polluted by the test materials, and animals may cause oral infections by licking their fur.

[0008] The head exposure device clamps the neck of the animal to expose its head to the flowing aerosol. The advantage of this exposure device is that it partially solves the problem of oral or skin infection of experimental animals. The disadvantage is that the head of the animal is still exposed. In test aerosols, head contamination and transocular conjunctival infection were not addressed

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