11 results about "ANIMAL EXPOSURE" patented technology

The application belongs to the technical field of toxicity test, and discloses a high-repetitive and high-precision exposure and poisoning animal experiment system and method. The exposure and poisoning animal experiment system comprises an animal exposure and poisoning experiment unit. The aerosol gas inlet sleeve, the poisoning exposure cabin, the isolation mouse cage, the horn-shaped upper guide cylinder and the cylindrical lower guide cylinder jointly form two mutually isolated poisoning exposure channels. Each channel independently inputs poisoning exposure mixed gas into a poisoning exposure chamber. The animal poisoning exposure experiment in the oral-nasal exposure mode or the whole-body exposure mode can be completed by using one set of experiment system. Through the synchronous improvement of the experiment system structure and the experiment method, the oral-nasal or whole-body exposure mode can be flexibly switched, and the micro-sample high-concentration exposure experiment of multiple poisoning exposure chambers can be simultaneously performed. The accuracy and repeatability of the animal poisoning exposure experiment are significantly improved. The application breaks through the limitations of the existing experiment system and method, and has a wide application prospect.

The utility model discloses animal expelling equipment for power supply and distribution facilities, which comprises an expelling device body, a protective shell is arranged on the outer side surface of the expelling device body, a plurality of groups of barbs are arranged on the outer side surface of the protective shell, the plurality of groups of barbs are distributed on the outer side surface of the protective shell in an annular array, and the barbs are arranged on the outer side surface of the protective shell. A transparent window is arranged on the upper surface of the protective shell, a driving box is arranged below the expeller body, ground nails are installed on the lower surface of the driving box, and a forward and reverse motor is arranged in the driving box. According to the animal expelling device, the barbs are adopted, the uncomfortable feeling when animals make contact with the expelling device can be increased through the barbs, when the animals attempt to approach or touch the expelling device with the barbs, the barbs can stimulate the skin or claws of the animals to make the animals feel painful or uncomfortable, and therefore the animals fear the expelling device, and attack behaviors are reduced.

The application belongs to the technical field of toxicity test, and discloses a kind of on-site synchronous experimental device, experimental method and application of animal atmosphere exposure, the device includes modular design and detachable connection main portable box and exposure experimental unit, vice portable box and experimental support unit, can be flexibly carried to various environmental event sites, and at any time, quickly carry out animal exposure experiment;Multiple exposure cabins, multiple concentration exposure experimental design can carry out multiple concentration gradient experiments in the same time, and can complete toxicity evaluation experiment in a shorter time.The device and method provided by the application can use on-site atmosphere as exposure research object at any time, carry out toxicity evaluation experiment of multiple concentration conditions environmental air in the same time, obtain more real and effective experimental data under real experimental conditions, to solve the problem of rapid health risk assessment of on-site pollution environment event and improve the accuracy of evaluation results.

The utility model discloses an animal medicine animal fixing device which comprises a bottom plate, a fixing fence is fixedly arranged on one side of the upper end of the bottom plate, a fixing mechanism used for fixing an animal is arranged in the fixing fence, and the fixing mechanism comprises a fixing plate, a fixing bandage, an electric push rod and a connecting rope. A fixing plate is fixedly arranged on one side of the surface of the fixing fence, a fixing rope is arranged at the lower end of the interior of the fixing fence, a plurality of electric push rods are arranged on the two sides of the surface of the fixing fence, connecting ropes are fixedly arranged at the four corners of the outer side surface of the fixing bandage, and the connecting ropes are fixedly connected with the movable ends of the electric push rods. The animal fixing fence is good in use effect, animals can be lured into the fixing fence and then bound and fixed, manual contact with the animals is not needed in the whole process, and therefore when blood drawing or other medical detection is carried out on the animals subsequently, the animals can be safely operated only by standing on the two sides of the fixing fence, and operation is convenient. Therefore, the use effect of the device can be improved.

The invention discloses a behavior analysis device and a monitoring device. The behavior analysis device comprises a constant-voltage power supply module; a conductive platform; the first conductive piece is connected with the high-potential end; the second conductive part is connected with the low-potential end and the conductive platform; a conductive layer is arranged at a first position of the insulating part, and the conductive layer is connected with the first conductive part; the conducting layer can be in contact with an animal at the first position, and when the animal is in contact with the conducting layer, a loop is formed between the high-potential end and the low-potential end, and an electric signal is generated and used for representing behaviors of the animal; the sampling module is used for collecting an electric signal of a first duration and generating a monitoring result based on the collected electric signal; the electric signal comprises a current signal and / or a voltage signal of the loop; and the analysis module is used for acquiring the monitoring result and analyzing the electric signal in the monitoring result to determine a behavioral index. According to the behavior analysis device, manual participation is not needed when the monitoring result is determined, and the obtained monitoring result is relatively objective, high in accuracy and high in efficiency.

The present application relates to an experimental animal positioning system and method, which comprises: an operable positioning mechanism, including a bearing part bearing the torso of an experimental mouse and a fixing part adjustably bearing the limbs of the experimental mouse, wherein the fixing part has a first identification part; a movable clamping mechanism for positioning the experimental mouse to the positioning mechanism and having a second identification part; an identification unit for forming a modulation instruction for controlling the fixing part according to the spatial position information of the first and second identification parts; and a driver assembly connected to the bearing part and adjustably mechanically coupled to the fixing part, capable of adjusting the spatial position of the fixing part in response to the modulation instruction. The present application provides an experimental animal positioning system, which guides the movement of the fixing part to the desired position through the specific identification segment of the clamping mechanism, and the adjustment process does not require disassembly of the fixing part, avoiding contact with the experimental animal, saving the time of body position adjustment, and ensuring the safety of the experimental personnel.

The invention provides a laboratory animal exposure device for particulate atmospheric pollutants, and particularly belongs to the technical field. Through the structural arrangement of the mixing box, the three-way valve connected with the mixing box and the air pump, the structure allows the system to be flexibly switched between an internal circulation mode and an external air supplementing mode; when long-term exposure of the animal living environment needs to be guaranteed, the air supply mode is switched to, and unification of experimental accuracy and animal ethics is achieved. The device comprises a pollutant generation and resuspension box, a mixing box and an animal exposure box which are sequentially arranged in the airflow direction; the mixing box is connected with an air pump and a three-way valve through pipelines, and three connectors of the three-way valve are connected with external air, the pollutant generation and resuspension box and the mixing box connected through the air pump respectively. The device can be switched between an internal circulation mode and an external air supplement mode from the pollutant generation and resuspension box to the mixing box and then to the pollutant generation and resuspension box.

This invention relates to the field of environmental chemistry and toxicology analysis technology, and particularly to a method for identifying bisphenol metabolites, comprising the following steps: S1: establishing a list of potential metabolites; S2: acquiring high-resolution mass spectrometry data of biological samples; S3: automated screening and identification: automatically processing the mass spectrometry data obtained in step S2 using mass spectrometry analysis software, including precursor ion identification and fragment ion matching analysis, comparing the analysis results with the list of potential metabolites generated in step S1, and screening out metabolites that match the mass spectrometry data as candidate identification results; this invention achieves rapid and accurate identification of target metabolites from massive amounts of mass spectrometry information through the steps of computational simulation to predict potential metabolites, obtaining real mass spectrometry data through animal exposure experiments, and automated software comparison and screening.

The utility model relates to an animal behavior observation box, which aims to solve the technical problems that an animal in an observation box is inconvenient to take out by a worker after the animal behavior observation is finished, so that the worker needs to grab the animal, the grabbing is strenuous, and the animal is easily accidentally injured, and comprises a transparent box body, a through hole is formed in one end of the transparent box body, two baffles are installed at the end, close to the through hole, of the transparent box body, the two baffles are arranged on the two sides of the through hole correspondingly, inserting grooves are formed in the opposite ends of the two baffles correspondingly, a partition plate is slidably connected between the two inserting grooves, and a limiting plate is fixedly connected to the top of the partition plate. Compared with the prior art, the animal grabbing device has the advantages that manual grabbing of workers is not needed when the animals after behavior observation is completed are grabbed, the animals are convenient to grab, unnecessary harm caused by contact between the workers and the animals is avoided, and the safety of grabbing the animals from the transparent box body is improved.

The present application relates to a method and system for detecting the sweetness perception threshold based on dynamic gradient feedback, and belongs to the technical field of animal behavior detection. The method comprises: configuring sucrose solutions with gradient concentrations; collecting the time and pressure of the animal contacting the bottle mouth respectively; calculating the contact proportion of the animal to the sucrose solution under each concentration; constructing a mathematical model to fit the relationship curve between the contact proportion and the concentration of the sucrose solution; determining whether there is a significant change in the animal's perception of the sugar concentration according to the slope, and determining the sweetness perception threshold; and inducing sugar solution aversion reaction to verify whether the threshold result is reliable. The present application introduces the L w slope of the value-concentration curve to analyze the sensitivity of the animal to sucrose solutions with different concentrations, which can effectively distinguish between physiological perception and random preference, and effectively improve the accuracy of sweetness perception threshold detection; and the calculation of L w integrates the double parameter indicators of contact time and licking pressure, further improving the accuracy of sweetness perception threshold detection.