20 results about "ANIMAL EXPOSURE" patented technology

The application belongs to the technical field of toxicity test, and discloses a high-repetitive and high-precision exposure and poisoning animal experiment system and method. The exposure and poisoning animal experiment system comprises an animal exposure and poisoning experiment unit. The aerosol gas inlet sleeve, the poisoning exposure cabin, the isolation mouse cage, the horn-shaped upper guide cylinder and the cylindrical lower guide cylinder jointly form two mutually isolated poisoning exposure channels. Each channel independently inputs poisoning exposure mixed gas into a poisoning exposure chamber. The animal poisoning exposure experiment in the oral-nasal exposure mode or the whole-body exposure mode can be completed by using one set of experiment system. Through the synchronous improvement of the experiment system structure and the experiment method, the oral-nasal or whole-body exposure mode can be flexibly switched, and the micro-sample high-concentration exposure experiment of multiple poisoning exposure chambers can be simultaneously performed. The accuracy and repeatability of the animal poisoning exposure experiment are significantly improved. The application breaks through the limitations of the existing experiment system and method, and has a wide application prospect.

The utility model discloses animal expelling equipment for power supply and distribution facilities, which comprises an expelling device body, a protective shell is arranged on the outer side surface of the expelling device body, a plurality of groups of barbs are arranged on the outer side surface of the protective shell, the plurality of groups of barbs are distributed on the outer side surface of the protective shell in an annular array, and the barbs are arranged on the outer side surface of the protective shell. A transparent window is arranged on the upper surface of the protective shell, a driving box is arranged below the expeller body, ground nails are installed on the lower surface of the driving box, and a forward and reverse motor is arranged in the driving box. According to the animal expelling device, the barbs are adopted, the uncomfortable feeling when animals make contact with the expelling device can be increased through the barbs, when the animals attempt to approach or touch the expelling device with the barbs, the barbs can stimulate the skin or claws of the animals to make the animals feel painful or uncomfortable, and therefore the animals fear the expelling device, and attack behaviors are reduced.

The invention discloses a multi-mode animal exposure device and method based on aerosol contamination, and relates to the technical field of biomedical experimental equipment. The device comprises an aerosol generating device, a breath exposure cabin and an exhaled air collecting device, the aerosol generating device comprises a gas source, a dispersed phase generating device and a mixing chamber which are connected in sequence; the breathing exposure cabin comprises an experimental animal fixing device; the breathing decoupling tube comprises a three-way tube internally provided with a one-way valve, the air inlet end is communicated with the mixing chamber, the breathing end is communicated with the respiratory tract of the experimental animal, and the air outlet end is communicated with an exhaled air collecting device. A dispersed phase output by a dispersed phase generating device and gas output by a gas source in the device can form aerosol with uniform properties in a mixing chamber, exhaled gas and inspired gas in a respiration decoupling pipe respectively flow through different gas passages, decoupling of inspiration and exhaling is realized, mutual interference between the two processes can be reduced, and the stability of the device is improved. And the result of the breathing exposure experiment is more accurate.

The application belongs to the technical field of toxicity test, and discloses a kind of on-site synchronous experimental device, experimental method and application of animal atmosphere exposure, the device includes modular design and detachable connection main portable box and exposure experimental unit, vice portable box and experimental support unit, can be flexibly carried to various environmental event sites, and at any time, quickly carry out animal exposure experiment;Multiple exposure cabins, multiple concentration exposure experimental design can carry out multiple concentration gradient experiments in the same time, and can complete toxicity evaluation experiment in a shorter time.The device and method provided by the application can use on-site atmosphere as exposure research object at any time, carry out toxicity evaluation experiment of multiple concentration conditions environmental air in the same time, obtain more real and effective experimental data under real experimental conditions, to solve the problem of rapid health risk assessment of on-site pollution environment event and improve the accuracy of evaluation results.

The present invention relates to the technical field of sample collection, and provides a skin sampling device that is convenient for collection and storage, including: a first housing and a second housing, and an installation opening is formed on the surface of the second housing. The sterile water is conveyed to the nozzle through a water pump, and the animal is cleaned through the nozzle. After the cleaning is completed, the intake fan allows the external gas to enter the air drying cover through the diversion cavity, and the air flow holes on the surface of the air drying cover are used to air-dry the animal skin. In addition, the electric telescopic rod drives the substrate to move downward, so that the swab paper on the surface of the magic tape is attached to the animal. While the swab paper is in contact with the animal, the sponge deforms under force, facilitating the swab paper to fit the animal surface. The motor drives the installation piece to rotate through the connecting shaft, and the swab paper is driven to rotate through the installation piece, the electric telescopic rod, the substrate, the buffer spring, the adjustment block, the sponge and the magic tape, so as to collect the sample on the surface of the animal skin.

The utility model discloses an animal medicine animal fixing device which comprises a bottom plate, a fixing fence is fixedly arranged on one side of the upper end of the bottom plate, a fixing mechanism used for fixing an animal is arranged in the fixing fence, and the fixing mechanism comprises a fixing plate, a fixing bandage, an electric push rod and a connecting rope. A fixing plate is fixedly arranged on one side of the surface of the fixing fence, a fixing rope is arranged at the lower end of the interior of the fixing fence, a plurality of electric push rods are arranged on the two sides of the surface of the fixing fence, connecting ropes are fixedly arranged at the four corners of the outer side surface of the fixing bandage, and the connecting ropes are fixedly connected with the movable ends of the electric push rods. The animal fixing fence is good in use effect, animals can be lured into the fixing fence and then bound and fixed, manual contact with the animals is not needed in the whole process, and therefore when blood drawing or other medical detection is carried out on the animals subsequently, the animals can be safely operated only by standing on the two sides of the fixing fence, and operation is convenient. Therefore, the use effect of the device can be improved.

The present application discloses an animal watering apparatus. The apparatus comprises a water tank assembly, the water tank assembly comprising a water storage tank, a water drinking tray, and a water guide pipe, the water storage tank defining a water storage cavity that has a top opening, the water drinking tray being detachably mounted on the water storage tank, and the water guide pipe being communicated with the water storage tank and the water drinking tray; a water pump, configured to enable water in the water storage tank to flow to the water drinking tray through the water guide pipe; and a guard, mounted on the water tank assembly, at least partially arranged on the water drinking tray and distributed in the circumferential direction of the water drinking tray, and dividing the upper portion of the water drinking tray into an isolation area for preventing an animal from coming into contact with the water drinking tray and a water drinking area for allowing an animal to come into contact with the water drinking tray. The animal watering apparatus provided by the technical solution of the present application facilitates controlling the number of pets that simultaneously drink water, and preventing hazards caused by a large number of pets drinking water around the water drinking tray.

The utility model relates to the technical field of electrical power engineering, in particular to a novel narrow-mouth bus which comprises a bus end connector, a novel narrow-mouth bus body and a dustproof cover plate are arranged in the bus end connector in a penetrating mode, and the opening of the novel narrow-mouth bus body and the dustproof cover plate are arranged in a mutual covering mode. The two ends of the opening of the novel narrow-mouth bus main body are provided with clamping head bends, the two ends of the dustproof cover plate are provided with clamping head protrusions, and the clamping head bends and the clamping head protrusions are mutually clamped and fixed. By optimizing the design, the exposed part of the bus is reduced, the risks of physical damage and animal contact are reduced, the safety and reliability of the system are ensured, and the heat dissipation performance is enhanced; the structural design is improved, so that a better heat dissipation effect is realized in a limited space, the working efficiency of the bus is improved, and the service life of the bus is prolonged; and by adopting the copper bar with the U-shaped structure, the contact surface is optimized, and the current-carrying capacity of the bus is improved, so that the requirement of higher power is met.

An ultrasound transducer for animals employs a crystal array with a novel combination of length, curvature, width, focus, operating frequency, and crystal pitch to optimize sonogram detail, resolution, field of view, and depth of view. The transducer includes a probe housing having a convex animal-contacting wall; and an array of piezoelectric crystals positioned along the convex wall. Properties of the transducer probe provide a shorter transducer length and smaller crystal element pitch to provide superior near field resolution, a more gradual resolution loss, and superior patient contact.

The invention discloses a behavior analysis device and a monitoring device. The behavior analysis device comprises a constant-voltage power supply module; a conductive platform; the first conductive piece is connected with the high-potential end; the second conductive part is connected with the low-potential end and the conductive platform; a conductive layer is arranged at a first position of the insulating part, and the conductive layer is connected with the first conductive part; the conducting layer can be in contact with an animal at the first position, and when the animal is in contact with the conducting layer, a loop is formed between the high-potential end and the low-potential end, and an electric signal is generated and used for representing behaviors of the animal; the sampling module is used for collecting an electric signal of a first duration and generating a monitoring result based on the collected electric signal; the electric signal comprises a current signal and / or a voltage signal of the loop; and the analysis module is used for acquiring the monitoring result and analyzing the electric signal in the monitoring result to determine a behavioral index. According to the behavior analysis device, manual participation is not needed when the monitoring result is determined, and the obtained monitoring result is relatively objective, high in accuracy and high in efficiency.

The present application relates to an experimental animal positioning system and method, which comprises: an operable positioning mechanism, including a bearing part bearing the torso of an experimental mouse and a fixing part adjustably bearing the limbs of the experimental mouse, wherein the fixing part has a first identification part; a movable clamping mechanism for positioning the experimental mouse to the positioning mechanism and having a second identification part; an identification unit for forming a modulation instruction for controlling the fixing part according to the spatial position information of the first and second identification parts; and a driver assembly connected to the bearing part and adjustably mechanically coupled to the fixing part, capable of adjusting the spatial position of the fixing part in response to the modulation instruction. The present application provides an experimental animal positioning system, which guides the movement of the fixing part to the desired position through the specific identification segment of the clamping mechanism, and the adjustment process does not require disassembly of the fixing part, avoiding contact with the experimental animal, saving the time of body position adjustment, and ensuring the safety of the experimental personnel.

The invention provides a laboratory animal exposure device for particulate atmospheric pollutants, and particularly belongs to the technical field. Through the structural arrangement of the mixing box, the three-way valve connected with the mixing box and the air pump, the structure allows the system to be flexibly switched between an internal circulation mode and an external air supplementing mode; when long-term exposure of the animal living environment needs to be guaranteed, the air supply mode is switched to, and unification of experimental accuracy and animal ethics is achieved. The device comprises a pollutant generation and resuspension box, a mixing box and an animal exposure box which are sequentially arranged in the airflow direction; the mixing box is connected with an air pump and a three-way valve through pipelines, and three connectors of the three-way valve are connected with external air, the pollutant generation and resuspension box and the mixing box connected through the air pump respectively. The device can be switched between an internal circulation mode and an external air supplement mode from the pollutant generation and resuspension box to the mixing box and then to the pollutant generation and resuspension box.

The invention relates to a sweet perception threshold detection method and detection system based on dynamic gradient feedback, and belongs to the technical field of animal behavior detection. The method comprises the following steps: preparing a sucrose solution with gradient concentration; respectively collecting the time and the pressure when the animal contacts the bottle mouth; calculating the contact ratio of the animal to the sucrose solution under each concentration; constructing a mathematical model section by section to fit a relation curve between the contact ratio and the concentration of the sucrose solution; judging whether the perception of the animal on the sugar concentration is obviously changed according to the slope, and determining a sweetness perception threshold value; and inducing a sugar solution aversion reaction to verify whether a threshold result is reliable or not. According to the method, the Lw value-concentration curve slope is introduced to analyze the sensitivity of animals to sucrose solutions with different concentrations, physiological perception and random preference can be effectively distinguished, and the accuracy of sweet perception threshold detection is effectively improved; and the calculation of Lw integrates two parameter indexes of contact time and licking pressure, so that the accuracy of sweet taste sensing threshold detection is further improved.

This invention relates to the field of environmental chemistry and toxicology analysis technology, and particularly to a method for identifying bisphenol metabolites, comprising the following steps: S1: establishing a list of potential metabolites; S2: acquiring high-resolution mass spectrometry data of biological samples; S3: automated screening and identification: automatically processing the mass spectrometry data obtained in step S2 using mass spectrometry analysis software, including precursor ion identification and fragment ion matching analysis, comparing the analysis results with the list of potential metabolites generated in step S1, and screening out metabolites that match the mass spectrometry data as candidate identification results; this invention achieves rapid and accurate identification of target metabolites from massive amounts of mass spectrometry information through the steps of computational simulation to predict potential metabolites, obtaining real mass spectrometry data through animal exposure experiments, and automated software comparison and screening.

The invention belongs to the technical field of toxicity testing, and discloses a high-repeatability and high-precision exposure contamination animal experiment system and method, and the exposure contamination animal experiment system comprises an animal exposure contamination experiment unit, an aerosol inlet sleeve, a contamination exposure cabin, an isolation mouse cage, a trumpet-shaped upper guide cylinder and a cylindrical lower guide cylinder of the unit jointly form two contamination exposure channels which are isolated from each other, and contamination exposure mixed gas is independently input into contamination exposure small chambers; animal contamination exposure experiments in a mouth and nose exposure mode or a whole body exposure mode can be completed through one experiment system. Through synchronous improvement of an experimental system structure and an experimental method, mouth-nose or whole-body exposure modes can be flexibly switched, a trace sample high-concentration exposure experiment of a plurality of contamination exposure chambers can be simultaneously carried out, the precision experiment and repeatability of an animal contamination exposure experiment are remarkably improved, and the experimental efficiency is improved. Various limitations of an existing experiment system and method are broken through, and the system and method have wide application prospects.

The present invention relates to the field of tobacco toxicology research, and specifically to an automatic loading experimental device for heated cigarette cartridges and an animal exposure smoking machine, comprising a hopper, a heating device, a loading mechanism and a unloading mechanism, wherein the hopper has a discharge port, the loading mechanism inserts the cartridge portion that has fallen off from the discharge port into the heating device, the unloading mechanism clamps the cartridge to separate the cartridge from the heating device, and the unloading mechanism comprises a cartridge clamp, which can separate the cartridge from the heating device with the axis of the cartridge as the rotation center. The present application overcomes the static friction between the cartridge and the heating device by rotating the cartridge, and the probability of tobacco residue remaining in the heating device is smaller, and the accuracy and continuity of subsequent loading of other cartridges are also higher, reducing manual intervention, and can ensure the stability of the fixation between the cartridge and the heating device after the cartridge is loaded.

The utility model relates to an animal behavior observation box, which aims to solve the technical problems that an animal in an observation box is inconvenient to take out by a worker after the animal behavior observation is finished, so that the worker needs to grab the animal, the grabbing is strenuous, and the animal is easily accidentally injured, and comprises a transparent box body, a through hole is formed in one end of the transparent box body, two baffles are installed at the end, close to the through hole, of the transparent box body, the two baffles are arranged on the two sides of the through hole correspondingly, inserting grooves are formed in the opposite ends of the two baffles correspondingly, a partition plate is slidably connected between the two inserting grooves, and a limiting plate is fixedly connected to the top of the partition plate. Compared with the prior art, the animal grabbing device has the advantages that manual grabbing of workers is not needed when the animals after behavior observation is completed are grabbed, the animals are convenient to grab, unnecessary harm caused by contact between the workers and the animals is avoided, and the safety of grabbing the animals from the transparent box body is improved.

The utility model discloses a bird inhabitation anti-collision protection device, and relates to the technical field of bird protection, the bird inhabitation anti-collision protection device comprises a vertical rod, the top end of the vertical rod is fixedly provided with a wind shielding barrel, the front surface of the wind shielding barrel is provided with an arch door, the top end of the wind shielding barrel is fixedly provided with a nest building net, and the surface of the bottom end of the vertical rod is rotatably sleeved with an anti-collision barrel; the rotating drum can freely rotate on the surface of the vertical rod through the bearing, other animals can be directly prevented from directly rubbing the vertical rod, the rotating rotating drum can be prevented from rubbing with animal skin, the interest of the animals on the vertical rod is reduced, in addition, certain buffering is provided when the animals make contact with the rotating drum through the arranged buffering assembly, and the animal can be prevented from being damaged. When the buffering assemblies provide buffering, the clamping heads can get close to each other, the skin of the animal attached to the buffering assemblies can be clamped, the animal can get away from the rotating cylinder when generating pain, and therefore the eagle attracting frame is further protected, and damage is reduced.

The present application relates to a method and system for detecting the sweetness perception threshold based on dynamic gradient feedback, and belongs to the technical field of animal behavior detection. The method comprises: configuring sucrose solutions with gradient concentrations; collecting the time and pressure of the animal contacting the bottle mouth respectively; calculating the contact proportion of the animal to the sucrose solution under each concentration; constructing a mathematical model to fit the relationship curve between the contact proportion and the concentration of the sucrose solution; determining whether there is a significant change in the animal's perception of the sugar concentration according to the slope, and determining the sweetness perception threshold; and inducing sugar solution aversion reaction to verify whether the threshold result is reliable. The present application introduces the L w slope of the value-concentration curve to analyze the sensitivity of the animal to sucrose solutions with different concentrations, which can effectively distinguish between physiological perception and random preference, and effectively improve the accuracy of sweetness perception threshold detection; and the calculation of L w integrates the double parameter indicators of contact time and licking pressure, further improving the accuracy of sweetness perception threshold detection.