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Blood analyzer and method for determining existence and nonexistence of lymphoblasts in blood sample

A technology of blood analyzers and blast cells, which is applied in the field of blood analyzers and can solve the problems of being unable to correctly detect whether there are lymphoblasts

Active Publication Date: 2010-10-06
SYSMEX CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, the presence or absence of lymphoblastoid cells cannot be detected correctly

Method used

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  • Blood analyzer and method for determining existence and nonexistence of lymphoblasts in blood sample
  • Blood analyzer and method for determining existence and nonexistence of lymphoblasts in blood sample
  • Blood analyzer and method for determining existence and nonexistence of lymphoblasts in blood sample

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Embodiment Construction

[0110] Specific embodiments of the present invention will be described below with reference to the accompanying drawings.

[0111] The present embodiment relates to a blood analyzer for detecting lymphoblasts in the blood sample by preparing a measurement sample by mixing a blood sample and a fluorescent dye for staining nucleic acid, and measuring the measurement sample with an optical flow cytometer.

[0112] [Structure of blood analyzer]

[0113] figure 1 It is an external perspective view of the blood analyzer according to this embodiment. The blood analyzer 1 according to the present embodiment is a multi-item blood cell analyzer that detects white blood cells, red blood cells, platelets, etc. from blood cells contained in a blood sample, and counts the various blood cells. Such as figure 1 As shown, the blood analyzer 1 has a measurement unit 2 , a sample transport unit 4 arranged in front of the measurement unit 2 , and an information processing unit 5 capable of con...

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Abstract

The invention provides a blood analyzer which enables the detection of lymphoblasts without the use of high-priced fluorescence-labeled antibodies. The blood analyzer comprises a blood sample supply section, a sample preparation section for preparing an assay sample by mixing the blood sample with a nucleic acid-staining fluorescent dye, a light source for irradiating the assay sample, an optical detecting section for receiving fluorescence emitted from the irradiated assay sample and a controller for performing operations comprising detecting a cell group comprising lymphoblasts on the basis of the fluorescence received by the optical detecting section (23), and outputting an information on an appearance of the lymphoblasts in the blood sample.

Description

technical field [0001] The present invention relates to a blood analyzer for optically measuring blood samples and classifying cell groups contained in the blood samples into several categories. The invention also relates to a method for judging whether there are lymphoblasts in the blood sample. Background technique [0002] Red blood cells, platelets, and white blood cells are free in the plasma of peripheral blood. Examination of these cells by blood tests can provide a great deal of clinical information. Therefore, most samples are subject to inspection. A blood cell counter is used in the blood test. The number of red blood cells, platelets, white blood cells, and hemoglobin concentration in the blood is automatically measured by a blood cell counter. [0003] There are five types of white blood cells in normal peripheral blood: lymphocytes, monocytes, basophils, eosinophils and neutrophils. Most blood cell counters have the function of classifying the white blood ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01N1/30G01N1/38
CPCG01N33/49G01N21/05G01N15/1429G01N21/53G01N21/645G01N2015/1006G01N2035/0091G01N2035/0412G01N2015/1402G01N15/1459G01N2015/1477G01N2015/011G01N2015/012G01N2015/016
Inventor 片冈由起子辻智悠
Owner SYSMEX CORP
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