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Mixing device for liquid chromatography

A mixing device and liquid chromatography technology, applied in the direction of mixers, measuring devices, fluid mixers, etc., can solve the problems of insufficient mixer effect and achieve the effect of full radial mixing

Active Publication Date: 2011-06-29
DIONEX SOFTRON
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the effect of a mixer so constructed is sometimes not sufficient

Method used

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  • Mixing device for liquid chromatography
  • Mixing device for liquid chromatography
  • Mixing device for liquid chromatography

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] figure 1 The shown radial mixing device 1 comprises a tubular mixing channel 3 which can be as figure 1 Said is constructed in a straight line. Of course, the mixing channel 3 can also be curved.

[0033]In the interior 5 of the mixing channel 3 there is a drainage element 7 which has a helical configuration. In the exemplary embodiment shown, the helical drainage element 7 has four full turns of 360°.

[0034] figure 2 The helical drainage element 7 is shown separately in a perspective view and is made of a strip-shaped thin planar element which has been twisted about its longitudinal axis by a corresponding angle of rotation, which In the example shown this is 4×360°=1440°. The flat strip has spacer elements 11 on its long outer sides 9 . These spacing elements 11 can be as figure 2 The respective arrangements shown are at positions opposite each other on the outer sides 9 of the long sides. Of course, the spacer elements 11 can also be arranged on the outer...

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Abstract

The invention relates to a mixing device for liquid chromatography for radially mixing at least two liquids, especially for mixing at least two eluents in high-performance liquid chromatography, comprising a tube-shaped mixing line (3), to an end of which a mixture composed of at least two liquids can be fed, said mixture having radial inhomogeneities in the axial progression thereof, and comprising a spiral-shaped flow guide element (7) arranged in the mixing line (3). According to the invention, spacers are provided which ensure a predetermined distance between the radially outer front (9) of the spiral-shaped wall of the flow guide element (7) facing the inner wall of the mixing line (3) and the inner wall of the tube-shaped mixing line (3). The invention further relates to a mixing apparatus comprising such a radial mixing device, downstream of which a longitudinal mixing device is connected.

Description

technical field [0001] The invention relates to a mixing device for liquid chromatography for radially mixing at least two liquids, in particular for mixing at least two eluents in high-performance liquid chromatography, the mixing device has claim 1 Features of the preamble. Furthermore, the invention relates to a mixing device for liquid chromatography, in which such a radial mixing device is used, downstream of which a longitudinal mixing device is arranged for mixing at least two liquids in the axial direction of the flow process. Background technique [0002] In liquid chromatography, especially in high performance liquid chromatography (HPLC), it is generally required to mix at least two different eluents (Eluent) as uniformly as possible according to an ideal ratio. In particular, this mixing ratio can be varied over time. As a rule, two separate liquid streams (respectively originating from a pump) are supplied to the T-Stück via two lines or capillaries when the t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D15/16B01F5/06G01N30/34G01N30/36
CPCG01N30/34B01D15/16B01F5/0614G01N2030/347Y10T436/2575B01F25/4314
Inventor 约阿希姆·维切尔斯
Owner DIONEX SOFTRON