Medicine for reducing serum uric acid, preparation method thereof and purpose thereof

A blood uric acid and drug technology, applied in the field of blood uric acid-lowering drugs and their preparation, can solve the problems of repeated blood lipids, high potential risks, affecting the quality of life of patients, etc., and achieves inhibition of steatosis, good clinical efficacy, and protection of liver cells. Effect

Active Publication Date: 2013-08-28
CHIATAI QINGCHUNBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Hyperuricemia is a group of diseases caused by purine metabolism disorder or decreased excretion of uric acid. Clinically asymptomatic hyperuricemia is very common. If hyperuricemia cannot be controlled in time, urates will be deposited in the kidneys. Or joints and other tissues, causing pathological changes, is the inducing factor of gout, diabetes, coronary heart disease and other peripheral vascular diseases, the potential risk is very high, seriously affects the quality of life of patients, increases the medical burden, most of the clinical treatment of hyperuricemia All chemical synthetic drugs have certain toxicity and side effects, and the abnormality reappears after stopping the drug.
At the same time, the incidence of hyperuricemia and hyperlipidemia caused by a high-purine and high-fat diet also showed a significant upward trend. Although blood lipid regulating drugs have good curative effects, there are blood lipid recurrences after drug withdrawal, or varying degrees. Side effects, high price, etc.

Method used

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  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof
  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof
  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of pharmaceutical granules of the present invention.

[0026] [Prescription] Arrowhead Mushroom 167g Smilax Smilax 1000g Sangji 500g Salvia 500g

[0027] Astragalus 500g Coix seed 1000g Gentiana 333g

[0028] 【Preparation】

[0029] A. According to the prescription, weigh Sanzigu, Smilax, Sangji, Raw Astragalus, Salvia, Coix Seed, and Gentiana for later use;

[0030] B. Put the raw material medicine into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and start timing when the temperature in the tank reaches 100°C; filter when the temperature in the tank drops to 70°C to obtain filtrate I, add 8 times Measure water and decoct for 1.5 hours, obtain filtrate II according to the method for obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifugate, centrifugation speed 3000rpm, centrifugation time 20min;

[0031] C. Input the centrifugate into the concentrator, contr...

Embodiment 2

[0043] Preparation of pharmaceutical tablet of the present invention.

[0044] [Prescription] Arrowhead Mushroom 167g Smilax Smilax 1000g Sangji 500g Salvia 500g

[0045] Astragalus 500g Coix seed 1000g Gentiana 333g

[0046] 【Preparation】

[0047] A. According to the prescription, weigh Sanzigu, Smilax, Sangji, Raw Astragalus, Salvia, Coix Seed, and Gentiana for later use;

[0048]B. Put the raw material medicine into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and start timing when the temperature in the tank reaches 100°C; filter when the temperature in the tank drops to 70°C to obtain filtrate I, add 8 times Measure water and decoct for 1.5 hours, obtain filtrate II according to the method for obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifugate, centrifugation speed 3000rpm, centrifugation time 20min;

[0049] C. Input the centrifugate into the concentrator, control ...

Embodiment 3

[0054] The preparation of medicine capsule of the present invention

[0055] [Prescription] Arrowhead Mushroom 167g Smilax Smilax 1000g Sangji 500g Salvia 500g

[0056] Astragalus 500g Coix seed 1000g Gentiana 333g

[0057] 【Preparation】

[0058] A. According to the prescription, weigh Sanzigu, Smilax, Sangji, Raw Astragalus, Salvia, Coix Seed, and Gentiana for later use;

[0059] B. Put the raw material medicine into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and start timing when the temperature in the tank reaches 100°C; filter when the temperature in the tank drops to 70°C to obtain filtrate I, add 8 times Measure water and decoct for 1.5 hours, obtain filtrate II according to the method for obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifugate, centrifugation speed 3000rpm, centrifugation time 20min;

[0060] C. Input the centrifugate into the concentrator, control t...

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PUM

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Abstract

The invention which belongs to the field of traditional Chinese medicines discloses a medicine for reducing serum uric acid, a preparation method thereof and a purpose thereof. The medicine is prepared from the following medicinal materials, by weight, 5-15 parts of edible tulip bulb, 10-60 parts of Smilax glabra, 6-30 parts of parasitic loranthus, 9-45 parts of Radix Astragali, 10-30 parts of Savia miltiorrhiza, 10-60 parts of coix seed, and 9-20 parts of Gentiana macrophylla. The medicinal materials are subjected to technologies of decoction, concentration, impurity removal, drying and the like to obtain effective parts for reducing serum uric acid, and the effective parts can be prepared into different clinically acceptable dosage forms with routine methods. The purpose comprises applications in preparing medicines for reducing serum uric acid, blood fat and protecting livers and kidneys, and applications of medicines for treating hyperuricacidemia or concurrent hyperuricacidemia. The medicine of the present invention which has effects of reducing serum uric acid, blood fat and protecting livers and kidneys can be used for treating hyperuricacidemia or concurrent hyperuricacidemia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a medicine for reducing blood uric acid, a preparation method and application thereof. Background technique [0002] Hyperuricemia is a group of diseases caused by purine metabolism disorder or decreased uric acid excretion. Clinically asymptomatic hyperuricemia is very common. If hyperuricemia cannot be controlled in time, urates will be deposited in the kidneys. Or joints and other tissues, causing pathological changes, is the inducing factor of gout, diabetes, coronary heart disease and other peripheral vascular diseases, the potential risk is very high, seriously affects the quality of life of patients, increases the medical burden, most of the clinical treatment of hyperuricemia All the chemical synthetic drugs have certain toxicity and side effects, and the abnormality reappears after stopping the drug. At the same time, the incidence of hyperuricemi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61P19/06A61P3/06
Inventor 徐红王佩
Owner CHIATAI QINGCHUNBAO PHARMA
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