Bladder cancer patient urine specific metabolite spectrum, establishing method and application
A bladder cancer, specific technology, applied in measurement devices, instruments, scientific instruments, etc., can solve problems such as invasiveness, achieve high specificity, good application prospects, and suitable for large-scale screening.
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[0017] The embodiments of the present invention will be described in detail below in conjunction with examples, but those skilled in the art will understand that the following examples are only used to illustrate the present invention and should not be regarded as limiting the scope of the present invention.
[0018] One aspect of the present invention provides a method for establishing a subject's urine metabolite profile, including the following steps:
[0019] (1) Sample collection and processing: the urine samples of the subjects are collected and processed to remove protein and other macromolecules;
[0020] (2) Liquid chromatography mass spectrometry analysis and determination: The metabolite spectrum in urine is obtained by the method based on liquid chromatography and mass spectrometry, and the metabolic spectrum is analyzed.
[0021] Another aspect of the present invention provides a method for establishing a urine-specific metabolite profile of patients with bladder cancer, w...
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