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Poria extract pellet and preparation method thereof

A technology of Poria cocos extract and pellets, applied in the field of medicine and food, can solve the problems of low bioavailability, gastric mucosal irritation, long disintegration time, etc., and achieves good effectiveness, low dosage of auxiliary materials, and good effect reproduction. sexual effect

Inactive Publication Date: 2012-05-23
JF PHARMALAND TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the products of Poria cocos extract are well received by consumers. These products are basically ordinary tablets and capsules, but the above-mentioned dosage forms have a long disintegration time; The mucous membrane is irritating to a certain extent; the disadvantages such as low bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A poria cocos extract pellet preparation, the pharmaceutical auxiliary materials are excipients and binders, wherein the poria cocos extract weight percentage in the pellet preparation is 5%, the excipient weight percentage is 85%, and the adhesive The percentage composition of agent is 10%, prepares qualified micropill preparation.

Embodiment 2

[0047] A poria cocos extract pellet preparation, the pharmaceutical auxiliary materials are excipients and binders, wherein the poria cocos extract weight percentage in the pellet preparation is 80%, the excipient weight percentage is 15%, and the adhesive The percentage content of agent is 5%.

Embodiment 3

[0049] A poria cocos extract pellet preparation, the pharmaceutical auxiliary materials are excipients and binders, wherein the poria cocos extract weight percentage in the pellet preparation is 24%, the excipient weight percentage is 74.5%, the adhesive The percentage content of agent is 1.5%.

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PUM

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Abstract

The invention provides a poria extract pellet preparation, which is prepared from a poria extract and pharmaceutical auxiliary materials and is characterized in that the auxiliary materials comprise an excipient and an adhesive; and in the pellet preparation, the weight percentage of the poria extract is 5-80%, the weight percentage of the excipient is 19-85% and the percentage of the adhesive is 1-10%. The pellet preparation can be prepared into a sustained-release or intestine-soluble preparation as required. Pharmacological experiments show that the pellet provided by the invention has good actions of enhancing immune function, protecting liver and the like.

Description

technical field [0001] The invention relates to the technical field of medicine and food, in particular to a pellet made of Poria cocos extract and a preparation method thereof. Background technique [0002] Poria cocos is the dried sclerotia of Polyporaceae fungus Poria cocos (Schw.) Wolf. Parasitic on the roots of pines such as red pine or masson pine, wild or cultivated, mainly produced in Yunnan, Anhui, Hubei, Henan, Sichuan and other places. The main component of Poria cocos extract is Poria cocos polysaccharide, which has the functions of enhancing immune function, protecting liver, reducing gastric juice secretion and inhibiting gastric ulcer. [0003] At present, the products of Poria cocos extract are well received by consumers. These products are basically ordinary tablets and capsules, but the above-mentioned dosage forms have a long disintegration time; The mucous membrane is irritating to a certain extent; the bioavailability is low and other disadvantages. B...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/076A61K9/16A61K9/00A61P37/04A61P1/16A61P1/04A23L1/28
Inventor 魏洪君
Owner JF PHARMALAND TECH DEV
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