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Traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and hepatic fibrosis

A technology for chronic hepatitis and liver fibrosis, applied in the direction of digestive system, drug combination, pharmaceutical formula, etc., can solve the problems of HBeAg's insignificant effect, high recurrence rate, and large adverse reactions, so as to achieve reasonable compatibility, prevent liver cirrhosis, and promote The effect of liver cell regeneration

Inactive Publication Date: 2012-06-27
SHAANXI UNIV OF CHINESE MEDICINE
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AI Technical Summary

Problems solved by technology

Chemical drugs represented by nucleoside drugs have the disadvantages of high recurrence rate after drug withdrawal and no obvious effect on HBeAg, while biological drugs represented by interferon also have high recurrence rate and adverse reactions in the treatment of HBV
However, most of the known traditional Chinese medicine preparations are common compound preparations, such as Gandujing Granules, Bganjiedu Capsules, etc. There are fewer drugs belonging to the category above the effective part, and those that belong to the combination preparation of the effective part and are both resistant and protective are used for the treatment of acute Drugs for hepatitis, chronic hepatitis and liver fibrosis are still rare

Method used

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  • Traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and hepatic fibrosis
  • Traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and hepatic fibrosis
  • Traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and hepatic fibrosis

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Embodiment Construction

[0018] The technical solutions of the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0019] To preliminarily explore the mechanism of the combination of Aralia taibai and Yexiazhu in treating damp-heat toxins, and to explore the ratio of the two. Method: Observe the prescription composed of the two in a certain ratio: the total saponins of Aralia taibai and the total polyphenols of Phyllostachys chinensis are respectively 1:1, 1:2, 1:3, 2:1, 2:2, 2:3 , 3:1, 3:2, 3:3 compatibility against hepatitis B virus in vitro, anti-CCl in vivo and in vitro 4 Liver function caused by acute liver cell injury and the impact of acute liver injury on liver function. Results: The in vitro and in vivo experiments showed that drug A had a good anti-hepatocyte injury effect, and drug B had a good anti-hepatitis B virus effect, and had inhibitory effects on both HBsAg and HbeAg. The combination of drug A and dr...

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Abstract

The invention discloses traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and hepatic fibrosis. The traditional Chinese medicine is characterized in that the traditional Chinese medicine is prepared by raw materials including, by weight percentage, from 25 to 50% of total saponin of aralia taibaiensis and from 50 to 75% of total polyphenol of phyllanthus urinaria. The traditional Chinese medicine has the advantages of scientific prescription, convenience in preparation, good curative effect, safety and zero side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating acute hepatitis, chronic hepatitis and liver fibrosis. Background technique [0002] In the field of clinical medicine today, liver system diseases have always been one of the diseases that cause human death, and acute hepatitis, chronic hepatitis and liver fibrosis are the most common frequently-occurring diseases in liver system diseases. Hepatitis is widely spread all over the world, and the incidence rate is on the rise. Chronic hepatitis has the characteristics of long course of disease, lingering and difficult to heal, and eventually leads to liver cirrhosis and liver cancer. Well-known international companies have included the treatment of hepatitis drugs as a key topic, and our country has also included it in the research content of key problems. Because hepatitis B is caused by hepatitis B virus, the most ideal way to treat he...

Claims

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Application Information

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IPC IPC(8): A61K36/47A61P1/16
Inventor 郭东艳唐志书郭伟
Owner SHAANXI UNIV OF CHINESE MEDICINE
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