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Animal tail suspension experiment device

An experimental device and tail suspension technology, which are applied in the fields of restraining animals, medical science, veterinary instruments, etc., can solve the problems of artificial counting, easy to be interfered, and the tail clipping instruments are easy to pinch off the tail of animals, and achieve anti-interference ability. Strong, easy to use, and the effect of eliminating the interference of human factors

Active Publication Date: 2012-08-22
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problems that the tail-clamping instrument in the current tail-suspension experiment is easy to pinch off the animal's tail, count artificially, and be easily disturbed, the present invention proposes an animal that provides suitable clamping force, eliminates interference from human factors, and has strong anti-interference ability. Tail Suspension Experimental Device

Method used

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  • Animal tail suspension experiment device
  • Animal tail suspension experiment device
  • Animal tail suspension experiment device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The animal tail suspension experimental device of the present invention comprises a base 1, a support 2, a tail gripper 3, a sensor locator 4, and a control device 5. The bottom end of the support 2 is fixed on the base 1, and the upper end is It is connected with the tail clamp 3; the sensor positioner 4 is electrically connected with the control device 5;

[0039] The sensor positioner 4 includes a mounting shaft 41 and a U-shaped rotating handle 42, the lower end of the mounting shaft 41 is fixed on the base 1, and the U-shaped rotating handle 42 is installed on the mounting shaft 42. On the upper end of the shaft 41, the two ends of the U-shaped rotary handle 42 are tilted up to be U-shaped. One end of the U-shaped rotary handle 42 is equipped with an infrared signal emitting tube and a positioning signal source, and the other end is installed with the described U-shaped rotary handle 42. An infrared signal receiving tube matched with the infrared signal transmittin...

Embodiment 2

[0059] Using the device in Example 1, carry out the tail-suspension experiment of mice. According to the animal behavior: when the mice are just tail-suspended, they struggle violently. After a few seconds, when the head is relatively calm, the red dot of the laser is aimed at the mouse’s forehead. , when the countdown is set in advance, press the start button to start the experiment.

[0060] According to animal habits: tail-suspended mice are susceptible to struggle due to the influence of the surrounding environment. Therefore, during the experiment, the entire experimental rack was shielded with a C-shaped box without a cover.

[0061] On the finally successfully developed instrument, 30 cases of white mice experiments were carried out. The weight of the white mice was 15-25g, and the total length of the body and tail was 150-190mm. The experimental time of a single white mouse was set at 5-25min. A tail suspension experiment was performed for 5-25 minutes, each section wa...

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Abstract

The invention relates to an animal tail suspension experiment device, comprising a base, a bracket, a tail clamper, a sensing locator and a control device; a bottom end of the bracket is fixed on the base, an upper end is connected with the tail clamper; the sensing locator is electrically connected with the control device; the sensing locator comprises a mounting shaft and an U-shaped rotating handle; a lower end of the mounting shaft is fixed on the base; the U-shaped rotating handle is mounted on the upper end of the mounting shaft; two ends of the U-shaped rotating handle raise up to be U-shaped; an end of the U-shaped rotating handle is equipped with an infrared signal transmitting tube and a located signal source, the other one end is equipped with an infrared signal receiving tube matched with the infrared signal transmitting tube; the infrared signal transmitting tube, the located signal source and the infrared signal receiving tube are controlled by the control device. The animal tail suspension experiment device provided by the invention has the advantages that proper clamping force is provided, man-made interference is removed, anti-jamming capability is strong, operations are simple, and use is convenient.

Description

technical field [0001] The invention relates to an animal tail suspension experiment device. Background technique [0002] Animal tail suspension experiment is widely used in the development of antidepressant drugs, stimulant drugs, sedative drugs and related health products. Depressed and immobile state is a method to evaluate the efficacy of the above drugs. However, some operational troubles and judgment errors are often encountered during the experiment, such as pinching off animal tails, artificial counting and interference signals, etc. For this purpose, a head displacement detection method with bionic tail pinching function and strong anti-interference ability was developed. Automatic detection device for tail suspension experiment. As a new automatic detection method for this experiment, it has an optimistic prospect of being popularized and applied in the industry. [0003] Similar experiments currently use handwriting and video playback methods, stress detection...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61D3/00G05B19/04
Inventor 葛尔宁黄真丁红梅侯晓丽丁兴红徐莉朱飞叶盛振华季巾君任学聪惠恩键方文忠
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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