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Glucose tolerance test and compositions therefor

A technology of glucose and composition, applied in the field of liquid nutritional composition, can solve the problems of consuming large sugar water, unpleasant, hindering people from accepting tests and the like

Inactive Publication Date: 2015-11-25
NV NUTRICIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Another disadvantage of the OGTT is that it requires the subject to consume large amounts of sugar water, which is often an unpleasant experience
This unpleasant procedure can deter people from taking trials

Method used

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  • Glucose tolerance test and compositions therefor
  • Glucose tolerance test and compositions therefor
  • Glucose tolerance test and compositions therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0120] Table 1 shows examples of liquid nutritional compositions according to the present invention.

[0121] Table 1

[0122]

[0123]

Embodiment 2

[0125] The glucose response of a composition according to the invention comprising 25 g of digestible carbohydrates ("MTT1.5") was compared to that of a glucose composition comprising 25 g of glucose dissolved in water ("glucose").

[0126] First, the effect on glucose levels in the blood was measured for persons who ingested the glucose composition after having fasted for at least 8 hours. Several days later, the effect on glucose levels in the blood was measured on the same person who ingested the digestible carbohydrate composition after having fasted for at least 8 hours. The result can be shown in figure 1 And in line with the findings of Meier et al. (Diabetes, Obesity and Metabolism, 11, 2009, 213–222).

Embodiment 3

[0128] Nutritional products intended for oral ingestion are liquid emulsions. The above emulsion has a small average particle size below 10 microns, and the amount of lipid particles with a diameter greater than 100 microns is less than 3 vol%.

[0129] The components as used during manufacture are (per 100ml):

[0130]

[0131] Pre-blended minerals and vitamins to meet Food for Special Medical Purpose (FSMP) requirements.

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Abstract

The present invention relates to a liquid nutritional composition, to a liquid nutritional composition for use in a diagnostic method for screening of a glucose-intolerant condition, to a kit for screening of a glucose-intolerant condition, and to a diagnostic method for screening a mammal for a glucose-intolerant condition. Furthermore, it refers to a liquid nutritional composition for use as a standard reference nutrition, such as for classification of postprandial glucose responses of different nutritional compositions. The liquid nutritional composition comprises protein, fat, digestible carbohydrate and dietary fibre, wherein the digestible carbohydrate comprises at least 90 weight % of glucose units, based on total digestible carbohydrate mass and preferably is substantially free of fructose.

Description

technical field [0001] The present invention relates to a liquid nutritional composition, a liquid nutritional composition used in a diagnostic method for screening glucose-intolerant conditions, a kit for screening glucose-intolerant conditions, and a Diagnostic method for screening mammals for glucose intolerance disorders. In addition, the present invention relates to liquid nutritional compositions used as standard reference nutrition, such as for classifying postprandial glucose responses of different nutritional compositions. Background technique [0002] Diabetes is a serious lifelong disease that can cause long-term complications that affect nearly every part of the body and lead to blindness, heart and blood vessel disease, stroke, kidney failure, amputations, and nerve damage. It is widely recognized as one of the leading causes of death and disability in the United States. Thus, early and appropriate diagnosis is critical to prevent and delay complications of di...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L1/29G01N33/50A23L33/00
CPCG01N33/49A23L1/293A23L1/308G01N33/48G01N33/66G01N2800/042A23L33/30A23L33/21
Inventor 罗伯特·约翰·约瑟夫·哈格曼米里安·兰辛克阿德里安乌斯·拉姆贝图斯·贝特霍尔德斯·范 赫尔福尔特克拉斯克·范 诺伦
Owner NV NUTRICIA
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