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Compound polyethylene glycol electrolyte powder and preparation method thereof

A technology of polyethylene glycol and electrolytes, applied in the field of medicine, can solve problems such as patient resistance and bad taste of the solution

Active Publication Date: 2012-12-05
SHENZHEN WANHE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] As with other laxatives and bowel cleansing compositions, many patients are taking or polyethylene glycol-based compositions to treat stagnant stools, the solution tastes bad
These adverse feelings can lead to the patient's resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Embodiment 1: preparation composition of the present invention

[0081] Formula (prepared on the basis of 10kg of total material per batch):

[0082] polyethylene glycol

[0083] Preparation method: crush polyethylene glycol and pass through a 50-mesh sieve, and crush the rest of the materials separately and pass through a 65-mesh sieve, and dry at 40-45°C for 2 hours; mix sodium chloride, potassium chloride, sodium bicarbonate, Anhydrous sodium sulfate, pineapple powder essence, and aspartame are uniformly mixed to obtain an electrolyte mixture; then the electrolyte mixture and polyethylene glycol are substantially uniformly mixed by an equal-volume increasing method to obtain the composition of the present invention, and encapsulated.

Embodiment 2

[0084] Embodiment 2: preparation composition of the present invention

[0085] Formula (prepared on the basis of 10kg of total material per batch):

[0086] polyethylene glycol

[0087] Preparation method: with embodiment 1.

Embodiment 3

[0088] Embodiment 3: preparation composition of the present invention

[0089] Formula (prepared on the basis of 10kg of total material per batch):

[0090] polyethylene glycol 3350

[0091] Anhydrous Sodium Sulfate

[0092] Preparation method: Mix sodium chloride, potassium chloride, sodium bicarbonate, anhydrous sodium sulfate, pineapple powder essence and aspartame after crushing and passing through 80 meshes to obtain an inorganic salt raw material mixture, and then mix the inorganic salt raw material mixture with the Grinding and passing through 65-mesh polyethylene glycol PEG is fed separately with two feeding hoppers, and packed into a packaging bag to obtain the final product. The ingredients of the pineapple powder essence used are as follows: 2.0 g of ethyl butyrate, 2.0 g of ethyl 2-methyl butyrate, 1.0 g of ethyl acetate, 0.5 g of ethyl 3-methylthiopropionate, 1.0 g of ethyl caproate, Allyl cyclohexylpropionate 0.9g, methyl butyrate 1.0g, pin...

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PUM

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Abstract

The invention relates to compound polyethylene glycol electrolyte powder and a preparation method thereof, in particular to a powder compound containing polyethylene glycol and electrolyte. The powder compound comprises, by weight, 6000 parts of polyethylene glycol, 118-176 parts of sodium chloride, 60-90 parts of potassium chloride, 137-205 parts of sodium bicarbonate, 461-692 parts of anhydrous sodium sulfate, 19-29 parts of powder essence, and / or 5-7.6 parts of aspartame. The compound polyethylene glycol electrolyte powder has fine micromeritic properties and taste.

Description

technical field [0001] The invention relates to the field of medicine, and relates to a composition containing polyethylene glycol and electrolytes and a preparation method thereof, in particular to a compound polyethylene glycol electrolyte powder and a preparation method thereof. The composition of the present invention can be used for treating constipation, fecal obstruction, fecal stagnation, gas spasm, flatulence, and can also be used for standing enema, colon purgative or colon cleansing. Background technique [0002] Constipation is a common condition that often causes discomfort. Stool retention in the colon and / or rectum can cause discomfort and headaches. In extreme cases, the presence of hard or dry stools in the rectum can cause prolonged constipation and painful stools. [0003] Many treatments for constipation have been developed, including dietary controls (eg, increasing the fiber content of foods and avoiding foods thought to cause constipation), laxatives...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61K9/14A61P1/10A61P1/14A61K33/04A61K33/00A61K31/77
Inventor 衷期群马双飞刘晓燕
Owner SHENZHEN WANHE PHARMA
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