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A kind of anti-dehydration oral liquid and application thereof

A technology of oral liquid and mannitol, which is applied in the field of anti-dehydration oral liquid and its pharmaceutical application, can solve the problems of amplified insulin response, unfavorable drug storage, and low electrolyte, so as to reduce the amplified insulin response, improve mental state, enhance The effect of stability

Active Publication Date: 2017-12-01
湖北凤凰白云山药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing drugs for the treatment of acute diarrhea dehydration, such as oral rehydration salts, contain less electrolytes and cannot fully replenish the loss of various electrolytes. Secondly, the existing drugs are usually solid preparations and contain a large amount of inorganic salts that are prone to hygroscopic and water-absorbing crystals. Such as sodium chloride and potassium chloride, which are not conducive to the storage of drugs; in addition, the administration of glucose can lead to amplified insulin response; at the same time, dehydration usually leads to weakness and lack of energy

Method used

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  • A kind of anti-dehydration oral liquid and application thereof

Examples

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Effect test

Embodiment 1

[0020] Example 1: prescription: sodium chloride 1g, potassium chloride 0.5g, potassium hydrogen phosphate 2g, sodium citrate 0.5g, sodium lactate 0.5g, anhydrous glucose 4g; Mix evenly, add distilled water to dissolve, sterilize, and bottle.

Embodiment 2

[0021] Embodiment 2: prescription: sodium chloride 1g, potassium chloride 0.5g, potassium hydrogen phosphate 2g, sodium citrate 0.5g, sodium lactate 0.5g, anhydrous glucose 4g, mannitol 2g; The average particle diameter of mannitol is 200 μ m, Weigh each component according to the prescription ratio, mix each component evenly, add the same amount of distilled water as in Example 1 to dissolve, sterilize, and bottle.

Embodiment 3

[0022] Embodiment 3: prescription: sodium chloride 1g, potassium chloride 0.5g, potassium hydrogen phosphate 2g, sodium citrate 0.5g, sodium lactate 0.5g, anhydrous glucose 4g, maltodextrin 2g; Divide, each component is mixed uniformly, add the distilled water equivalent of Example 1 to dissolve, sterilize, bottle.

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PUM

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Abstract

The anti-dehydration oral liquid of the present invention comprises the following components: sodium chloride, potassium chloride, potassium hydrogen phosphate, sodium citrate, sodium lactate, glucose, maltodextrin, and mannitol. And has the following advantages: the oral liquid of the present invention can provide a stable buffer capacity, which is beneficial to keep the pH value of the cell fluid stable; when the dosage of glucose is reduced, the digestible sugar maltodextrin that will not cause an amplified insulin response is added, Thereby reducing the possibility of amplified insulin response; enhancing the storage stability of the drug, reducing the appearance of crystal precipitation and precipitation; increasing B vitamins, enabling the body to release energy and improving mental state; each component is in the whole solid preparation. A high level of homogeneity in the distribution.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to an anti-dehydration oral liquid and its pharmaceutical use. Background technique [0002] There are many situations in which a subject may suffer from dehydration and related deficiencies such as loss of mineral salts. For example, exercise acts to deplete the body's fuel reserves and increase the rate of perspiration, which results in loss of water and minerals. These losses can be significant if the exercise is prolonged and especially if the ambient temperature is moderate or high. Other situations that can lead to dehydration include as, for example, the effects of enterotoxins (such as cholera typically in the third world), the effects of viruses (such as rotavirus typically in the developed world) or rest after surgery (such as when GI When rest is important) excessive temperature results, loss of nutrition, fever, excessive diarrhea and vomiting. Alternatively, the condit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/42A61K47/36A61K47/26A61K9/08A61P7/08A61K31/047A61K33/14A61K31/716
Inventor 程雪翔
Owner 湖北凤凰白云山药业有限公司
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