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Healthcare product containing broad bean extracts and application of healthcare product

A technology of extracts and health products, which is applied to health products containing broad bean extract and its application field, can solve the problems that health ingredients and effects cannot be coordinated and complemented, health care effects are not outstanding, and ingredients are fixed and simple, etc., to achieve synergistic treatment of Parkinson's disease , improve health care function, strengthen the effect of specific efficacy

Active Publication Date: 2014-05-07
NANJING CORE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

From the perspective of health preservation in traditional Chinese medicine, a single broad bean product has the disadvantages of fixed and simple ingredients, insufficient efficacy, and insufficient rapid onset of effect
The broad bean extract is derived from the same plant, the ingredients are fixed and simple, and the same exogenous health ingredients and functions cannot be synergistic and complementary, and the recent health effects are not outstanding

Method used

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  • Healthcare product containing broad bean extracts and application of healthcare product
  • Healthcare product containing broad bean extracts and application of healthcare product
  • Healthcare product containing broad bean extracts and application of healthcare product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The fresh broad bean extract is prepared as follows:

[0017] Take fresh broad beans, screen, clean, squeeze and extract juice, let the squeezed juice stand overnight for precipitation, filter, and use the filtrate for later use; add appropriate amount of 75% ethanol to extract the broad bean dregs twice, each time for 1.5 hours, and extract the ethanol after recovering the ethanol and mix with the above The filtrates are combined, concentrated under reduced pressure to an extract with a relative density of 1.2-1.25 at 60°C, and spray-dried to obtain the broad bean extract.

[0018] Grape seed extract is prepared as follows:

[0019] Take grape seeds, screen, dry and crush, pass through a 60-mesh sieve, add 8 times the amount of 75% ethanol, and extract twice at 70°C for 1 hour each time, let the extract stand for precipitation, centrifuge, and collect The supernatant is recovered with ethanol, the supernatant is concentrated, the thick paste is dried, and crushed into...

Embodiment 2

[0021] Example 2 The protective effect of the composition on dopaminergic neurons in Parkinson's disease rats

[0022] Adult healthy Wistar male rats, weighing 180-200g. The Parkinson's disease rat model was made according to the improved Thomas method, and the successful Parkinson's disease rat model was randomly divided into a composition group (n=30) and a Parkinson's disease group (n=30). After the model was selected successfully, 1,7 , 14d is the observation time point. Rats in the composition group (ZH group) were given 2.5g / (kg·d) broad bean extract + 0.25g / (kg·d) grape seed extract by gavage at 9 o'clock every day according to their body weight, Parkinson's disease group (PD group) Rats were administered with normal saline until the observation point.

[0023] The Parkinson's disease rat model was made according to the improved Thomas method: 7% chloral hydrate (0.6ml / 100g) was used for intraperitoneal injection anesthesia, the head was fixed horizontally on the brai...

Embodiment 3

[0031] Example 3 Effect of Composition on Obese and Hyperlipidemic Mice

[0032] 4-week-old KM mice, half male and half female, were fed with high-fat feed (the formula of high-fat feed was casein 1kg, L-cysteine ​​15g, maltodextrin 0.75kg, sucrose 0.35kg, cellulose 0.25kg, soybean oil 0.15kg, lard 1.25kg). After feeding for 10 weeks, mice with body weight less than 50 g were eliminated, and then divided into the following groups: model control group, positive control group, and test group, with 12 mice in each group. Rats in each group were intragastrically administered with the test substance at the following doses, once a day at 12:00 for 8 weeks.

[0033] Model control group: equivalent purified water;

[0034] Positive control group: 5mg / (kg·d) rosuvastatin calcium;

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Abstract

The invention discloses a healthcare product containing broad bean extracts. An active ingredient comprises the broad bean extracts and grape seed extracts, and preferably, the weight ratio of the broad bean extracts to the grape seed extracts is 3-18:1. The broad bean extracts and the grape seed extracts are organically combined, so that ingredients such as flavones, polyphenols and phospholipids which are contained in natural substances of the broad bean extracts and natural substances of the grape seed extracts are recombined, effects of synergistically protecting dopaminergic neurons, losing weight and reducing blood lipid are achieved, defects of a healthcare product with a single ingredient comprising broad bean extracts are overcome, specific effects of the product are strengthened, and accordingly healthcare functions of the product can be effectively played and improved.

Description

technical field [0001] The invention belongs to the technical field of health food preparation, and in particular relates to a health product containing broad bean extract and its application. Background technique [0002] Broad bean is an annual or perennial leguminous plant, which is rich in trace elements such as phosphorus, magnesium, and selenium, and also contains water-soluble protein components with antioxidant activity; fresh broad beans are the best source of vitamin A and vitamin C. Contains a variety of flavonoids that have the effects of lowering blood fat, anti-arteriosclerosis, anti-tumor, and anti-osteoporosis. In addition, proanthocyanidins in broad beans have physiological activities such as anti-oxidation, antibacterial, anti-cancer, and anti-mutation. In recent years, the research on the nutrition, health care and medicinal value of broad bean has been in-depth, and the comprehensive development and utilization of broad bean resources has attracted widesp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L1/29A23L1/20A23L33/00A23L11/00
Inventor 王雪根张耀明何凌云陈强金皓洁汪洋
Owner NANJING CORE TECH CO LTD
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